|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Stem cells as delivery vehicles for regenerative medicinechallenges and perspectives显示文摘The use of stem cells as carriers for therapeutic agents is an appealing modality for targeting tissues or organs of interest. Combined delivery of cells together with various information molecules as therapeutic agents has the potential to enhance, modulate or even initiate local or systemic repair processes, increasing stem cell efficiency for regenerative medicine applications. Stem-cell-mediated delivery of genes, proteins or small molecules takes advantage of the innate capability of stem cells to migrate and home to injury sites. As the native migratory properties are affected by in vitro expansion, the existent methods for enhancing stem cell targeting capabilities(modified culture methods, genetic modification, cell surface engineering) are described. The role of various nanoparticles in eq-uipping stem cells with therapeutic small molecules is revised together with their class-specific advantages and shortcomings. Modalities to circumvent common challenges when designing a stem-cell-mediated targeted delivery system are described as well as future prospects in using this approach for regenerative medicine applications. | Luminita Labusca Dumitru Daniel Herea Kaveh Mashayekhi | 2018 | World Journal of Stem Cells2018，10，5： | 5 |
| 2 | Large mucinous biliary cystadenoma with 'ovarian-like'stroma:A case report显示文摘肝胆管包囊腺瘤是是困难的外科手术前地诊断的稀罕肿瘤。他们能到达使他们成为真实 intraoperative 的大尺寸“吃惊”。一个 63 岁的女人,与一个征兆的巨大的腹的膀胱的团介绍了,与安全边缘经历了团的完全的切除术。组织病理学说的报告与“象卵巢一样”揭示了粘蛋白的的肝的包囊腺瘤 sclerohyalinization 的基质和区域。占据正确的半腹部的大囊性瘤的鉴别诊断必须包括胆道囊肿腺瘤;有安全边缘的肿瘤的完全的切除术避免本地复发,因为疾病的恶意的潜力,因此代表最佳的治疗。手术后的后续包括腹的超声或 CT 扫描和 CA 19-9 测量。 | Mircea Beuran Mircea Dan Venter Laura Dumitru | 2006 | World Journal of Gastroenterology2006，12，23： | 4 |
| 3 | Super-resolution of geosynchronous synthetic aperture radar images using dialectical GANs显示文摘Dear editor,The concept of geosynchronous synthetic aperture radar (GEO SAR) system was conceived in an effort to realize a quick observation of emergency disasters (e.g., landslides and earthquakes)[1].The novel GEO SAR system has the significant advantages of short-revisit time and large coverage and facilitates the nearly continuous observation of target regions, unlike the currently operatinglow earth orbit (LEO) SARs [2]. | Yuanhao LI Dongyang AO Corneliu Octavian DUMITRU Cheng HU Mihai DATCU | 2019 | Science China(Information Sciences)2019，62，10： | 3 |
| 4 | Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial显示文摘 | Charles S Fuchs Jiri Tomasek Cho Jae Yong Filip Dumitru Rodolfo Passalacqua Chanchal Goswami Howard Safran Lucas Vieira dos Santos Giuseppe Aprile David R Ferry Bohuslav Melichar Mustapha Tehfe Eldar Topuzov John Raymond Zalcberg Ian Chau William Campbell | 2014 | The Lancet2014，，9911： | 3 |
| 5 | Aggregation Operators for Interval-Valued Pythagorean Fuzzy Soft Set with Their Application to Solve Multi-Attribute Group Decision Making Problem显示文摘Interval-valued Pythagorean fuzzy soft set(IVPFSS)is a generalization of the interval-valued intuitionistic fuzzy soft set(IVIFSS)and interval-valued Pythagorean fuzzy set(IVPFS).The IVPFSS handled more uncertainty comparative to IVIFSS;it is the most significant technique for explaining fuzzy information in the decision-making process.In this work,some novel operational laws for IVPFSS have been proposed.Based on presented operational laws,two innovative aggregation operators(AOs)have been developed such as interval-valued Pythagorean fuzzy soft weighted average(IVPFSWA)and interval-valued Pythagorean fuzzy soft weighted geometric(IVPFSWG)operators with their fundamental properties.A multi-attribute group decision-making(MAGDM)approach has been established utilizing our developed operators.A numerical example has been presented to ensure the validity of the proposed MAGDM technique.Finally,comparative studies have been given between the proposed approach and some existing studies.The obtained results through comparative studies show that the proposed technique is more credible and reliable than existing approaches. | Rana Muhammad Zulqarnain Imran Siddique Aiyared Iampan Dumitru Baleanu | 2022 | Computer Modeling in Engineering & Sciences2022，，6： | 3 |
| 6 | 一种新型液压马达——锥差式液压马达显示文摘液压锥差马达是一种新型液压马达,减速比大、矩功比高、能耗低、调速性能好。该型马达与一般液压马达相比具有全新的结构和功能,特别适用于低转速大转矩、高效率的领域。该课题研究了这种新型马达的原理和实现技术,包括配流转换技术、调速原理和方法、齿轮理论和多齿啮合性能、整机优化设计、样机试制和性能试验等。该项研究为国内空白,对于主机简化传动、节约能源、降低成本有着重要意义。 | 刘鹄然 Dumitru | 1998 | 液压与气动1998，22，6： | 2 |
| 7 | On the existence and the uniqueness theorem for fractional differential equations with bounded delay within Caputo derivatives显示文摘Local and global existence and uniqueness theorems for a functional delay fractional differential equation with bounded delay are investigated. The continuity with respect to the initial function is proved under Lipschitz and the continuity kind conditions are analyzed. | Thabet Abdeljawad MARAABA Fahd JARAD Dumitru BALEANU | 2008 | Science China Mathematics2008，51，10： | 2 |
| 8 | Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial显示文摘 | Charles S Fuchs Jiri Tomasek Cho Jae Yong Filip Dumitru Rodolfo Passalacqua Chanchal Goswami Howard Safran Lucas Vieira dos Santos Giuseppe Aprile David R Ferry Bohuslav Melichar Mustapha Tehfe Eldar Topuzov John Raymond Zalcberg Ian Chau William Campbell | 2014 | 2014 (9911)2014，，9911： | 2 |
| 9 | Hamiltonian Formulation of Singular Lagrangians on Time Scales显示文摘Lagrangian 的 Hamiltonian 明确的表达准时,规模被调查,哈密尔顿和 Euler-Lagrange 方程的等价被获得。Lagrange 的角色多,钳子被讨论。 | JARAD Fahd BALEANU Dumitru MARAABA Abdeljawad Thabet | 2008 | Chinese Physics Letters2008，25，5： | 2 |
| 10 | Twenty years of postharvest biocontrol research: Is it time for a new paradigm?显示文摘 | Samir Droby Michael Wisniewski Dumitru Macarisin Charles Wilson | 2008 | Postharvest Biology and Technology2008，，2： | 2 |
| 11 | Thrusting and exhumation around the margins of the western Tarim Basin during the Indina-Asia collision显示文摘 | Sobel E R Dumitru T A | 1997 | Journal of Geophysical Research1997，102，3： | 2 |
| 12 | Regeneration of neurotransmission transcriptome in a model of epileptic encephalopathy after antiinflammatory treatment显示文摘Inflammation is an established etiopathogenesis factor of infantile spasms(IS), a therapy-resistant epileptic syndrome of infancy. We investigated the IS-associated transcriptomic alterations of neurotransmission in rat hypothalamic arcuate nucleus, how they are corrected by antiinflamatory treatments and whether there are sex differences. IS was triggered by repeated intraperitoneal administration of N-methyl-D-aspartic acid following anti-inflammatory treatment(adreno-cortico-tropic-hormone(ACTH) or PMX53)or normal saline vehicle to prenatally exposed to betamethasone young rats. We found that treatments with both ACTH and PMX53 resulted in substantial recovery of the genomic fabrics of all types of synaptic transmission altered by IS. While ACTH represents the first line of treatment for IS, the even higher efficiency of PMX53(an antagonist of the complement C5 a receptor) in restoring the normal transcriptome was not expected. In addition to the childhood epilepsy, the recovery of the neurotransmission genomic fabrics by PMX53 also gives hope for the autism spectrum disorders that share a high comorbidity with IS. Our results revealed significant sex dichotomy in both IS-associated transcriptomic alterations(males more affected) and in the efficiency of PMX53 anti-inflammatory treatment(better for males). Our data further suggest that anti-inflammatory treatments correcting alterations in the inflammatory transcriptome may become successful therapies for refractory epilepsies. | Dumitru A.Iacobas Libor Velísek | 2018 | Neural Regeneration Research2018，13，10： | 2 |
| 13 | Recyling of PET显示文摘 | FIRAS Awaja DUMITRU Pavel | 2005 | European Polymer Journal2005，41，： | 1 |
| 14 | Late Oligocene-Early Miocene unroofing in the Chinese Tian Shan:An early effect of the India-Asia collision显示文摘 | Hendrix M S Dumitru T A Graham S A | 1994 | Geology1994，22，： | 1 |
| 15 | Review: Recycling of PET 显示文摘 | FIRAS A DUMITRU P L | 2005 | Eur Polym J2005，41，： | 1 |
| 16 | Complex permeability spectra of Ni-Zn ferrites doped with V2Os/Nb20s 显示文摘 | Parvatheeswara Rao B Cahun Ocidiu Dumitru Ioan | 2006 | Joumal of Magnetism and Mag- netic Materials2006，304，： | 1 |
| 17 | Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers显示文摘 | Calin GA~ Sevignani C~ Dumitru CD | 2004 | Proc Nail Acad Sci U S A2004，101，9： | 1 |
| 18 | A Novel Analytical Technique of the Fractional Bagley-Torvik Equations for Motion of a Rigid Plate in Newtonian Fluids显示文摘The current paper is concerned with a modified Homotopy perturbation technique.This modification allows achieving an exact solution of an initial value problem of the fractional differential equation.The approach is powerful,effective,and promising in analyzing some classes of fractional differential equations for heat conduction problems and other dynamical systems.To crystallize the new approach,some illustrated examples are introduced. | Mahmoud H.Taha Mohamed A.Ramadan Dumitru Baleanu Galal M.Moatimid | 2020 | Computer Modeling in Engineering & Sciences2020，，9： | 1 |
| 19 | Epidemiological Analysis of the Coronavirus Disease Outbreak with Random Effects显示文摘Today,coronavirus appears as a serious challenge to the whole world.Epidemiological data of coronavirus is collected through media and web sources for the purpose of analysis.New data on COVID-19 are available daily,yet information about the biological aspects of SARS-CoV-2 and epidemiological characteristics of COVID-19 remains limited,and uncertainty remains around nearly all its parameters’values.This research provides the scientic and public health communities better resources,knowledge,and tools to improve their ability to control the infectious diseases.Using the publicly available data on the ongoing pandemic,the present study investigates the incubation period and other time intervals that govern the epidemiological dynamics of the COVID-19 infections.Formulation of the testing hypotheses for different countries with a 95%level of condence,and descriptive statistics have been calculated to analyze in which region will COVID-19 fall according to the tested hypothesized mean of different countries.The results will be helpful in decision making as well as in further mathematical analysis and control strategy.Statistical tools are used to investigate this pandemic,which will be useful for further research.The testing of the hypothesis is done for the differences in various effects including standard errors.Changes in states’variables are observed over time.The rapid outbreak of coronavirus can be stopped by reducing its transmission.Susceptible should maintain safe distance and follow precautionary measures regarding COVID-19 transmission. | Muhammad Farman Aqeel Ahmad Ali Akgül Muhammad Umer Saleem Muhammad Naeem Dumitru Baleanu | 2021 | Computers, Materials & Continua2021，，6： | 1 |
| 20 | Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers显示文摘 | Calin GA Sevignani C Dumitru CD | 2004 | Proc Natl Acad Sci USA2004，101，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员