5篇
您的检索式：作者名="Duqiang LUO"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Two new compounds from an endophytic fungus Pestalotiopsis heterocornis显示文摘 | XING JIANGUANG DENG HUIYING LUO DUQIANG | | 0，，12： | 1 |
| 2 | Two new oxysporone derivatives from the fermentation broth of the endophytic plant fungus Pestalotiopsis karstenii isolated from stems of Camellia sasanqua显示文摘 | Luo Duqiang Zhang Lei Shi Baozhong | 2012 | Molecules2012，17，： | 1 |
| 3 | Study on Biotransformation of Natural Anti-tumor Drug Podophyllotoxin显示文摘[Objective] This study aimed to select stains for transforming podophyllotoxin,to isolate the transformation product and to identify the structure.[Method] Structure of podophyllotoxin was modified with microbial batch transformation method.Podophyllotoxin and its transformation products were detected by using TLC and HPLC methods to select strains with ability to transform podophyllotoxin.Scale-up fermentation of one podophyllotoxin-transforming strain was carried out and the fermented material was extracted with EtoAc,isolated with conventional silica gel column chromatography,structure of the transformation product was identified by using classic spectroscopy technology.[Result] Based on researches of podophyllotoxin transformation,seven strains with ability to transform podophyllotoxin were selected,including BS.Str-1,BS.Str-2,BS.Str-3,BS.Str-7,BS.Str-18,BS.Str-21 and BS.Str-29.By scale up fermentation,the only transformation product of BS.Str-21 strain was extracted and isolated,which was identified as picropodophyllotoxin.[Conclusion] This study demonstrates that podophyllotoxin derivatives can be obtained by biotransformation methods,which lays the foundation for acquisition of natural drugs with high anti-tumor activity. | Baozhong SHI Lei ZHANG Duqiang LUO | 2012 | Agricultural Biotechnology2012，1，3： | 0 |
| 4 | Setosphlides A-D, New Isocoumarin Derivatives from the Entomogenous Fungus Setosphaeria rostrate LGWB-10显示文摘Investigation of the entomogenous fungus Setosphaeria rostrate LGWB-10 from Harmonia axyridis led to the isolation of four new isocoumarin derivatives,setosphlides A-D(1-4),and four known analogues(5-8).Their planar structures and the relative configurations were elucidated by comprehensive spectroscopic methods.The absolute configurations of isocoumarin nucleus for 1-4 were elucidated by their ECD spectra.The C-10 relative configurations for the pair of C-10 epimers(1 and 2)were established by comparing the magnitude of the computed 13C NMR chemical shifts(Δδcalcd.)with the experimental 13C NMR values(Δδexp.)for the epimers.All of the isolated compounds(1-8)were evaluated for their cytotoxicities against four human tumor cell lines MCF-7,MGC-803,HeLa,and Huh-7. | Wenbin Gao Xiaoxia Wang Fengli Chen Chunqing Li Fei Cao Duqiang Luo | 2021 | Natural Products and Bioprospecting2021，11，1： | 0 |
| 5 | Selective recognition of HIV RNA by dinuclear metallic ligands显示文摘We describe the development of dinuclear metallic ligands to target specific HIV RNA structures. Two series of dipyridinyl-N bridged dinuclear metal complexes were synthesized in moderate to good yields and their binding activities toward TAR and RRE RNA were studied both experimentally and theoretically.The docking calculation elucidated some structure features in dimetallic complexes that can affect TAR RNA-binding properties. | Xuedong Li Bo Chen Ling Lan Ruili Wang Duqiang LUO Li Liu Liang Cheng | 2018 | Chinese Chemical Letters2018，29，11： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员