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19篇 您的检索式:作者名="E Fedeli"
    题名 作者 年代 出处 被引量
1Liver angiogenesis as a risk factor for hepatocellularcarcinoma development in hepatitis C virus cirrhotic patients显示文摘AIM: To evaluate the predictive value of hepatocyte proliferation and hepatic angiogenesis for the occurrence of Hepatocellular carcinoma (HCC) in hepatitis C virus (HCV) cirrhotic patients. METHODS: One hundred-five patients (69 males, 36 females; age range, 51-90 year; median 66 year) with biopsy proven HCV cirrhosis were prospectively monitored for HCC occurrence for a median time of 64 mo. Angiogenesis was assessed by using microvessel density (MVD), hepatocyte turnover by MIB1 and PCNA indexes at inclusion in liver biopsies. RESULTS: Forty six patients (43.8%) developed HCC after a median time of 55 (6-120) mo while 59 (56.2%) did not. Patients were divided into two groups according to the median value of each index. The difference between patients with low (median MVD = 3; range 0-20) and high (median MVD = 7; range 1-24) MVD was statistically significant (χ2 = 22.06; P < 0.0001) which was not the case for MIB1 or PCNA (MIB-1: χ2 = 1.41; P = 0.2351; PCNA: χ2 = 1.27; P = 0.2589). The median MVD was higher in patients who developed HCC than in those who did not. HCC-free interval was significantly longer in patients with the MVD ≤ 4 (P = 0.0006). No relationship was found between MIB1 or PCNA and MVD (MIB-1 r2 = 0.00007116, P = 0.9281; PCNA: r2 =0.001950; P = 0.6692). MVD only was able to predict the occurrence of HCC in these patients. Among other known risk factors for HCC, only male sex was statistically associated with an increased risk. CONCLUSION: Liver angiogenesis has a role for in HCV- related liver carcinogenesis and for defining patients at higher risk.Roberto Mazzanti Luca Messerini Camilla E Comin Lorenzo Fedeli Nathalie Gannè-Carrie Michel Beaugrand 2007World Journal of Gastroenterology2007,13,37:3
2Increasing incidence and mortality of infective endocarditis:a population-based study through a record-linkage system显示文摘Fedeli U Schievano E Buonfrate D 0,,:1
3Epidemiologic evidence of cancer risk in textile industry workers: a review and update显示文摘G Mastrangelo U Fedeli E Fadda 2002Toxicology and industrial health2002,18,4:1
4Increased cancer risk a-mong surgeons in an orthopaedic hospital显示文摘Mastrangelo G Fedeli U Fadda E 2005Occup Med(Lond)2005,55,6:1
5Increasing incidence and mortality of infective endocarditis:a population-based study through a record-linkage system显示文摘Fedeli U Schievano E Buonfrate D 0,,:1
6Increasing incidenceand mortality of infective endocarditis : a population - based studythrough a record - linkage system 显示文摘Fedeli U Schievano E Buonfrate D 2011BMC Infectious Diseases2011,11,1:1
7查看详情显示文摘Guider R Daldosso N Pitanti A Jordana E Fedeli J M Pavesi L 0,,:1
8Increased risk of hepatocellular carcinoma and liver cirrhosis in vinyl chloride workers: Synergistic effect of occupational exposure with alcohol intake 显示文摘Mastrangelo G Fedeli U Fadda E 2004Environ Health Perspect2004,112,11:1
9Hypogonadism and hormone re- plaeement therapy on hone mass of adult women with thalassemia major 显示文摘Carmina E Di Fede G 2004Calcified Tissue International2004,74,1:1
10Targeting of onokaryop hiliccell permeable peptides into the nuclei of intact cells by covalently at tacked nuclear localization signals显示文摘 Fede rR MorA 2002Biochemistry2002,41,29:1
11Recombinant human erythropoietin treatment in cisplatin-associated anemia: a randomized,double-blind trial with placebo显示文摘 Fedeli A Del Ferro E 1994J Clin Oncol1994,12,5:1
12Targeting o fonokaryophilic cell-permeable peptides into the nuclei of intact cells by covalently attached nuclear localization signals显示文摘Hariton Gazal E Fede rR Mor A 2002Biochemistry2002,41,29:1
13Recombinant human erythropoietin treatment in cisplatin associated anemia : aran - domized, double blind trial with placebo显示文摘Cascinu S Fedeli A Del Ferro E 1994J Clin Oncol1994,12,5:1
14Immunization with the cysteine proteinase Ldccys1 gene from Leishmania (Leishmania) chagasi and the recombinant Ldccys1 protein elicits protective immune responses in a murine model of visceral leishmaniasis显示文摘Josie Haydée L. Ferreira Luciana Girotto Gentil Suzana Souza Dias Carlos Eduardo C. Fedeli Simone Katz Clara Lúcia Barbiéri 2007Vaccine2007,,5:1
15Targeting o fonokaryophiliccell2permeable pep tides into the nuclei of intact cells by covalently attached nuclear localization signals显示文摘Hariton Gazal E Fede rR MorA 2002Bio chemistry2002,41,29:1
16Synthesis of polystyrene-grafted celluloseacetate copolymers via nitroxide-mediatedpolymerization 显示文摘MOREIRA G FEDELI E ZIARELLI F 2015Polym Chem2015,6,:1
17Minor components of vegetable oils:non - glyceridic esters 显示文摘MARIANI C FEDELI E 1989Riv Ital Sostanze Gr1989,66,7:1
18Increasing incidence and mortality of infective endocarditis: a population-based study through a record-linkage system显示文摘Fedeli U Schievano E Buonfrate D 2011BMC Infectious Diseases2011,,:1
19Space-frequency analysis and experimental measurement of magnetic field emissions radiated by high-speed railway systems显示文摘D Bellan G Spadacini E Fedeli 2015IEEE Transactions on Electromagnetic Compatibility2015,55,6:1
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