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| 1 | Spatiotemporal microRNA profile in peripheral nerve regeneration:miR-138 targets vimentin and inhibits Schwann cell migration and proliferation显示文摘While the peripheral nervous system has regenerative ability,restoration of sufficient function remains a challenge.Vimentin has been shown to be localized in axonal growth fronts and associated with nerve regeneration,including myelination,neuroplasticity,kinase signaling in nerve axoplasm,and cell migration;however,the mechanisms regulating its expression within Schwann cell(SC) remain unexplored.The aim of this study was to profile the spatial and temporal expression profile of micro RNA(mi RNA) in a regenerating rat sciatic nerve after transection,and explore the potential role of mi R-138-5 p targeting vimentin in SC proliferation and migration.A rat sciatic nerve transection model,utilizing a polyethylene nerve guide,was used to investigate mi RNA expression at 7,14,30,60,and 90 days during nerve regeneration.Relative levels of mi RNA expression were determined using microarray analysis and subsequently validated with quantitative real-time polymerase chain reaction.In vitro assays were conducted with cultured Schwann cells transfected with mi RNA mimics and assessed for migratory and proliferative potential.The top seven dysregulated mi RNAs reported in this study have been implicated in cell migration elsewhere,and GO and KEGG analyses predicted activities essential to wound healing.Transfection of one of these,mi RNA-138-5 p,into SCs reduced cell migration and proliferation.mi R-138-5 p has been shown to directly target vimentin in cancer cells,and the luciferase assay performed here in rat Schwann cells confirmed it.These results detail a role of mi R-138-5 p in rat peripheral nerve regeneration and expand on reports of it as an important regulator in the peripheral nervous system. | Travis B.Sullivan Litchfield C.Robert Patrick A.Teebagy Shannon E.Morgan Evan W.Beatty Bryan J.Cicuto Peter K.Nowd Kimberly M.Rieger-Christ David J.Bryan | 2018 | Neural Regeneration Research2018，13，7： | 6 |
| 2 | 胰腺偶发囊肿的管理--美国放射学院(ACR)偶发病变委员会白皮书显示文摘美国放射学院(American College of Radiology,ACR)偶发病变委员会(Incidental Findings Committee,IFC)发布了CT或MR偶发胰腺囊肿的管理建议。该建议是对美国放射学院杂志(JACR)2010年发布的肾上腺、肾脏、肝脏以及胰腺偶发病变管理白皮书中胰腺部分的更新。该管理方案由多位腹部影像医师、1位胃肠道学医师以及1位胰腺外科医师所组成的胰腺亚组委员会制定。该方案参考已发表的文献和专家意见,经反复协商,最终达成共识。该方案的分支成功地根据患者的临床特点及影像特征将胰腺囊肿进行分类,评估终点为良性和/或进展缓慢病变的诊断(足以结束随访)或具体的管理建议。该方案适用于大多数但非全部的病理及临床情况。该方案旨在通过提供胰腺偶发囊肿的管理指导,来提高患者的管理质量。 | Alec J.Megibow Mark E.Baker Desiree E.Morgan Ihab R.Kamel Dushyant V.Sahani Elliot Newman William R.Brugge Lincoln L.Berland Pari V.Pandharipande 赵心明 曾蒙苏 薛华丹 刘再毅 石喻 | 2018 | 放射学实践2018，33，2： | 2 |
| 3 | Exploitative Learning and Entrepreneurial Orientation Alignment in Emerging Young Firms: Implications for Market and Response Performance显示文摘 | MathewHughes PaulHughes Robert E.Morgan | 2007 | British Journal of Management2007，，： | 1 |
| 4 | Associations Between Message Features and Subjective Evaluations of the Sensation Value of Antidrug Public Service Announcements显示文摘 | Susan E.Morgan PhilipPalmgreen Michael T.Stephenson Rick H.Hoyle Elizabeth P.Lorch | 2006 | Journal of Communication2006，，3： | 1 |
| 5 | Market Orientation, Generative Learning, Innovation Strategy and Business Performance Inter‐Relationships in Bioscience Firms显示文摘 | Robert E.Morgan PierreBerthon | 2008 | Journal of Management Studies2008，，8： | 1 |
| 6 | 使命传承 推进ASTM服务于各利益相关方显示文摘我即将于2月1日接任ASTM国际标准组织总裁一职,这令我激动不已。两年前,我就开始为接任总裁一职做准备,并且有幸同我们的董事会成员一起协作,刷新ASTM国际标准组织的使命宣言。每个字都是精挑细选而来,当然我相信,这样的使命宣言也反应了我们存在的意义以及价值所在。自1984年我在这一伟大的机构开始职业生涯以来,我一直为我所做的工作感到自豪,我们努力工作着, | Katharine E.Morgan | 2017 | 中国标准化2017，，2： | 0 |
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