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5篇 您的检索式:作者名="E.Peters"
    题名 作者 年代 出处 被引量
1中国陆地水元素组成的中子活化分析试验显示文摘对同期降水、江河水和地下水的元素组成,使用中子活化分析方法作了对比试验。降水取自分布于8个气候带的11个站,其海拔高程为5~3659m,年平均降水量为50~1571mm。河水取自各主要江河包括内陆河和海岛的12个测站以及3个实验流域,并在其附近采集地下水。降水中共检出35种元素,各站有19~31种元素,同期均有空间分布。河水中共检出39种元素,各河分别有21~31种元素。地下水中共检出35种元素,各站有30~32种元素。对其浓度组成作了由大于1000μg/L至小于0 01μg/L的分级综合。有些元素含量超出所报道的世界淡水浓度范围,小于其最低值,甚或远大于其最高值。顾慰祖 陆家驹 陈廷扬 徐其高 Norman E.Peters 2003水科学进展2003,14,5:2
2Apoptosis inhibitor of macrophage and diabetic kidney disease显示文摘Dear Editor,Miyazaki et al.recently reviewed the role of the apoptosis inhibitor of macrophage(AIM)protein,also known as CD5 antigen-like(CD5L),as an apoptosis inhibitor that supports the survival of macrophages and protects against disease when it is in its free‘attacker’form after release from its circulating‘carrier’IgM.1 In particular,during acute kidney injury(AKI),evidence suggests that AIM is released systemically from the IgM pentamer,resulting in increased urinary excretion of free AIM,which exerts its local scavenging activity.Timothy M.E.Davis Kirsten E.Peters Richard Lipscombe 2019Cellular & Molecular Immunology2019,16,5:1
3In Vivo <sup>31</sup>P NMR Spectroscopy of Human Musculoskeletal Tumors as a Measure of Response to Chemotherapy显示文摘Harald E.M?ller PeterVermathen ErnstRummeny KlausW?rtler PaulusWuisman AlbertR?ssner BernardW?rmann J?rgRitter Peter E.Peters 1998NMR Biomed1998,,8:1
4Comparison of wing morphology in three birds of prey: Correlations with differences in flight behavior显示文摘Elaine L.Corvidae Richard O.Bierregaard Susan E.Peters 2006J Morphol2006,,5:1
5Rationally designed mariner vectors for functional genomic analysis of Actinobacillus pleuropneumoniae and other Pasteurellaceae species by transposon-directed insertion-site sequencing (TraDIS)显示文摘Comprehensive identification of conditionally essential genes requires efficient tools for generating high-density transposon libraries that, ideally, can be analysed using next-generation sequencing methods such as Transposon Directed Insertion-site Sequencing (TraDIS). The Himar1 (mariner) transposon is ideal for generating near-saturating mutant libraries, especially in AT-rich chromosomes, as the requirement for integration is a TA dinucleotide, and this transposon has been used for mutagenesis of a wide variety of bacteria. However, plasmids for mariner delivery do not necessarily work well in all bacteria. In particular, there are limited tools for functional genomic analysis of Pasteurellaceae species of major veterinary importance, such as swine and cattle pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida, respectively. Here, we developed plasmids, pTsodCPC9 and pTlacPC9 (differing only in the promoter driving expression of the transposase gene), that allow delivery of mariner into both these pathogens, but which should also be applicable to a wider range of bacteria. Using the pTlacPC9 vector, we have generated, for the first time, saturating mariner mutant libraries in both A. pleuropneumoniae and P. multocida that showed a near random distribution of insertions around the respective chromosomes as detected by TraDIS. A preliminary screen of 5000 mutants each identified 8 and 14 genes, respectively, that are required for growth under anaerobic conditions. Future high-throughput screening of the generated libraries will facilitate identification of mutants required for growth under different conditions, including in vivo, highlighting key virulence factors and pathways that can be exploited for development of novel therapeutics and vaccines.Janine T.Bossé Yanwen Li Leon G.Leanse Liqing Zhou Roy R.Chaudhuri Sarah E.Peters Jinhong Wang Gareth A.Maglennon Matthew T.G.Holden Duncan J.Maskell Alexander W.Tucker Brendan W.Wren Andrew N.Rycroft Paul R.Langford on behalf of the BRaDPT consortium 2021Animal Diseases2021,1,4:0
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