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1Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg 2017现代生物医学进展2017,17,27:3
2Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19.Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral 2021Cellular & Molecular Immunology2021,18,9:2
3Industrial Development Policies and Performances in Southern Chi- na: Beyond the Specialised Industrial Cluster Program显示文摘Elisa Barbieri Marco R 13I Tommaso Stefano Bonnini 2011China Economic Review2011,,6:1
4Mental Workload and Visual Impairment: Differences be- tween Pupil, Blink, and Subjective Rating 显示文摘Miguel A R Elisa P Angela C 2008The Spanish Journal of Psychology2008,11,2:1
5Clay minerals for adsorption of veterinary FQs: Behavior and modeling 显示文摘ELISA R ANNA P MICHELA S 2014Journal of Environmental Chemical Engineering2014,2,1:1
6Ultrasound in enzymatic resolution of ethyl 3-hydroxy-3-phenylpropanoate 显示文摘Carlos Magno R Ribeiro Elisa N Passaroto Eugenia C S Brenelli 2001Tetrahedron Letters2001,42,:1
7Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene☆显示文摘Victor R Gordeuk Angela Caleffi Elena Corradini Francesca Ferrara Russell A Jones Oswaldo Castro Onyinye Onyekwere Rick Kittles Elisa Pignatti Giuliana Montosi Cinzia Garuti Innocent T Gangaidzo Z.A.R Gomo Victor M Moyo Tracey A Rouault Patrick MacPhail A 2003Blood Cells Molecules and Diseases2003,,3:1
8Autoantibody to insulin receptor spontaneously developed as nati-idiotyped mice immunized through the rat blood-brain barrier in vivo显示文摘 Maron R Elisa D 1995Brain Res1995,683,2:1
9LHMDS mediated tandem acylation-cycliza- tion of 2-aminobenzenecarbonitriles with 2-benzymidazol- 2-yl acetates:a short and efficient route to the synthesis of 4-amino-3-benzimidazol-2-ylhydroquinolin-2-ones 显示文摘William R Antonios-McCrea Kelly A Frazier Elisa M Jazan 2006Tetrahedron Letters2006,47,:1
10Trypsin from viscera of vermiculated sailfin catfish, Pterygoplichthys disjunctivus, Weber, 1991:Its purification and characterization显示文摘Ana G V Juan C R Elisa M V 2013Food Chem2013,141,2:1
11Stern cell approaches for kidney repair:choosing the right cells显示文摘Costanza S Elisa R Elena L 2008Mol Med2008,14,7:1
12High-resolution DNA a nalysis of human embryonic stem cell lines reveals culture-in duced copy number changes and loss of heterozygosity 显示文摘Elisa N Reija A Nelly R 2010Nature Biotechnology2010,28,4:1
13Biomimetic polymer- ization of aniline using hematin supported on halloysite nanotubes 显示文摘Elisa T Jorge R G Paulina R 2010Applied Catalysis A : General2010,381,:1
14Correlation between c-Jun and hu-man papillomavirus in oral premalignant and malignant lesions显示文摘Renata R A Elisa D S 2008Oral Oncology2008,44,:1
15Dual inhibition of Bel -2 and Bcl - xL strikingly enhances PI3K inhibition - induced apoptosis in human myeloid leukemia ceils through a GSK3 - and Bim - de- pendent mechanism显示文摘Mohamed R Mandy MA Elisa A 2012Cancer Res2012,73,4:1
16Sexual function of the aging Male显示文摘Giovanni C Giulia R Elisa M 2013Best Prac & Res Clin Endocrin & Metabol2013,,27:1
17Eukaryotic elongation factor 2 controls TNF-[alpha] translation in LPS-induced hepatitis显示文摘González-Terán Bárbara Cortés José R Manieri Elisa Matesanz Nuria Verdugo ángeles Rodríguez María E González-Rodríguez águeda Valverde ángela Martín Pilar Davis Roger J Sabio Guadalupe 2013Journal of Clinical Investigation2013,,1:1
18Vertical metrology using scanning-probe microscopes: Imaging distortions and measurement repeatability显示文摘 McGlothlin R Elisa U 1998Applied Physics1998,83,8:1
1925- Hydroxyvitamin D and cardiovascular risk factors in women with systemic lupus erythematosus 显示文摘Wu Peggy W Rhew Elisa Y Dyer Alan R 2009Arthritis Rheum2009,10,61:1
20Investigations on optical, structural and thermal properties of phosphate glasses containing terbium ions显示文摘M Elisa B A Sava I C Vasiliu R C C Monteiro C R Iordanescu I D Feraru L Ghervase C Tanaselia M Senila B Abraham 2013IOP Conference Series: Materials Science and Engineering2013,,1:1
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