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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 2 | Age-related changes in the avian primary lymphoid organs (thymus and bursa of Fabricius)显示文摘 | Emilia C Pablo P P Belen D | 2003 | Mierosc Res Techniq2003，62，： | 1 |
| 3 | A rapid and simple procedure for the determination of synephrine in dietary supplements by gas chromatography-mass spectrometry显示文摘 | Emilia M Simona P Roberta P et ol | 2006 | J Pharmaceut Biomed2006，41，： | 1 |
| 4 | Purification,Partial characterization and mode of action of enterococcin EFS2,an antilisterial bacteriocin produced by a swain of Enterococcusfaecalis isolation from a cheese显示文摘 | Sophie M P Emilia F Richard J | 1996 | International Journal of Food Microbiology1996，30，： | 1 |
| 5 | Purification, Partial characterization and mode of action of enterococcin EFS2,an antilisterial bacteriocin produced by a strain of of Enterococcus faecalis isolation from a cheese显示文摘 | Sophie M P Emilia F Richard J | 1996 | Int J Food Microbiol1996，30，6： | 1 |
| 6 | Biomarkers in the dentin-pulp complex: role in health and disease 显示文摘 | Emilia E Neelakantan P | 2015 | J Clin Pediatr Dent2015，39，2： | 1 |
| 7 | Effect of Ischemic Preconditioning on Rat Liver Microcirculation Monitored with Laser Doppler Flowmetry显示文摘 | Attila Szijártó Oszkár Hahn Gábor Lotz Zsuzsa Schaff Emilia Madarász Péter Károly Kupcsulik | 2006 | Journal of Surgical Research2006，，1： | 1 |
| 8 | A rapid and simple procedure for the determination of ephedrine alkaloids in dietary supplements by gas chromatography - mass spectrometry 显示文摘 | Emilia M ManuelaP Roberta P | | Journal of pharmaceutical and biomedical analysis0，41，5： | 1 |
| 9 | BCR-ABL rearrangement is not detectable in essential thrombocythemia显示文摘 | Emilia G Marasca R Zucchini P | 2001 | Blood2001，97，： | 1 |
| 10 | Biomarkers in the dentin-pulp com- plex: role in health and disease 显示文摘 | Emilia E Neelakantan P | 2015 | J Clin Pediatr Dent2015，39，2： | 1 |
| 11 | Redox potential and substituent effects in ferrocene derivatives: Ⅱ显示文摘 | Emilia M N Silva P R A Armando J L | 1994 | J Organomet Chem1994，480，： | 1 |
| 12 | Spore germination and gametophyte development in three species of Asplenium显示文摘 | EMILIA P STUART L ADRIANDYER | 1994 | Annals of Botany1994，73，： | 1 |
| 13 | DNase I sensitivity of the chromatin of the yeast SUC2 gene for invertase显示文摘 | José E. Pérez-Ortin Francisco Estruch Emilia Matallana Luis Franco | 1986 | MGG Molecular & General Genetics1986，，3： | 1 |
| 14 | Helicobacter pylori infection and chronic immune thrombocytopenic purpura: long- term results Of bacterium eradication and association with bacterium virulence profiles显示文摘 | Emilia G Luppi M Zucchini P | 2007 | Blood2007，110，12： | 1 |
| 15 | Expression of telomerase genes correlates with telomerase activity in human colorectal carcinogenesis显示文摘 | Pu Yan Emilia P | 2001 | J Pathol2001，193，1： | 1 |
| 16 | A rapid and simple procedure for the determination of cannabinoids in hemp food products by gas chromatography-mass spectrometry显示文摘 | Manuela P Emilia M Roberts P | 2005 | Journal of Pharmaceutical and Biomedical Analysis2005，36，： | 1 |
| 17 | Gypsum scale control by nit- rilotrimethylenephosphonic acid 显示文摘 | Marina P Emilia O Amedeo L | 2009 | Ind Eng Chem Res2009，，10： | 1 |
| 18 | Optical transport networks employing all-optical wavelength conversion: limits and features显示文摘 | Eugenio I Emilia P | 1996 | IEEE Journal on Selected Areas in Communications1996，14，5： | 1 |
| 19 | Extension of nursery culture of ScyU serrata juveniles in net cages and ponds 显示文摘 | EDUARD M R FE D P EMILIA T Q | 2007 | aquaculture Research2007，38，： | 1 |
| 20 | Microfluidic Paper-Based Devices for Bioanalytical Applications显示文摘 | Murilo Santhiago Emilia W N Glauco P S | | 0，，01： | 1 |
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