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| 1 | Current trends of liver cirrhosis in Mexico: Similitudes and differences with other world regions显示文摘AIM To investigate the main current etiologies of cirrhosis in Mexico.METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period(January 2012-December 2017). RESULTS A total of 1210 patients were included. The mean age was 62.5 years(SD = 12.1), and the percentages of men and women were similar(52.0% vs 48.0%). The most frequent causes of liver cirrhosis were hepatitis C virus(HCV)(36.2%), alcoholic liver disease(ALD)(31.2%), and nonalcoholic steatohepatitis(23.2%), and the least frequent were hepatitis B virus(1.1%), autoimmune disorders(7.3%), and other conditions(1.0%).CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease(NAFLD) as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico. | Nahum Méndez-Sánchez Felipe Zamarripa-Dorsey Arturo Panduro Emma Purón-González Edgar Ulises Coronado-Alejandro Carlos Alejandro Cortez-Hernández Fátima Higuera de la Tijera José Luis Pérez-Hernández Eira Cerda-Reyes Heriberto Rodríguez-Hernández Vania César Cruz-Ramón Oscar Lenin Ramírez-Pérez Nancy Edith Aguilar-Olivos Olga Fabiola Rodríguez-Martínez Samantha Cabrera-Palma Guillermo Cabrera-álvarez | 2018 | World Journal of Clinical Cases2018，6，15： | 2 |
| 2 | Collapsing glomerulopathy associ ated with inherited mitochondriai injury显示文摘 | Barisoni L Diomedi-Camassei F Santorelli F M Caridi G Thomas D B Emma F | 2008 | Kidney Int2008，74，： | 1 |
| 3 | Clinicians' Attitudes to Clinical Practice Guidelines: a systematic review显示文摘 | Emma W K Jean R S | 2002 | MJA2002，177，9： | 1 |
| 4 | The negativeeffects of bile acids and tumor necrosis factor-αon the tran-scription of cholesterol 7α-hydroxylase gene(CYP7A1)con-verge to hepatic nuclear factor-4显示文摘 | Emma De F Nico M Ana Cecilia A | 2001 | J Biol Chem2001，276，30： | 1 |
| 5 | Intracellular electrolytes regulate the volume set point of the organic osmolytel anion channel(VSOACs)显示文摘 | Emma F Mcmanns M Strange K | 1997 | Am J Physiol1997，272，： | 1 |
| 6 | Ligation of TLR9 induced on human IL-10-secreting Tregs by 1[alpha],25-dihydroxyvitamin D3 abrogates regulatory function显示文摘 | Urry Zo? Xystrakis Emmanuel Richards David F McDonald Joanne Sattar Zahid Cousins David J Corrigan Christopher J Hickman Emma Brown Zarin Hawrylowicz Catherine M | 2009 | Journal of Clinical Investigation2009，，2： | 1 |
| 7 | Eculizumab for the treatment of dense-deposit disease显示文摘 | Vivarelli M Pasini A Emma F | 2012 | N Engl J Med2012，366，12： | 1 |
| 8 | Treatment of C3 glomerulopathy with com-plement blockers显示文摘 | Vivarelli M Emma F | 2014 | Semin Thromb Hemost2014，40，4： | 1 |
| 9 | Supporting structures for team situation awareness and decision making:insights from four delivery suites显示文摘 | Nicola M Emma J Della F | 2009 | J Eval Clin Pract2009，15，1： | 1 |
| 10 | Reactions of alkenes with ozone in the gas phase: A matrix-isolation study of secondary ozonides and earbonyl-eontaining reaction products显示文摘 | Emma J F Matthew J A George M | 2000 | Speetroehimiea Aeta2000，56，： | 1 |
| 11 | Virueidal activity of polysaccharide extracts from four algal species against herpes simplex virus显示文摘 | EMMA A H RUTH F SUSAN M | 2009 | Antiviral Research2009，83，3： | 1 |
| 12 | Treatment of C3 glomernlopathy with complement blockers 显示文摘 | Vivarelli M Emma F | 2014 | Semin Thromb Hemost2014，40，4： | 1 |
| 13 | The Negative Effects of Bile Acids and Tumor Necrosis Factor-α on the Transcription of Cholesterol 7α-Hydroxylase Gene (CYP7A1) Converge to Hepatic Nuclear Factor-4 显示文摘 | Emma De F Nico M Ana Cecilia A | 2001 | J Biol Chem2001，276，30： | 1 |
| 14 | Regulation of K-Cl cotransport by protein phosphatase 1alpha in mouse erythrocytes显示文摘 | EMMA V M ANDREA B | 2006 | Pflugers Arch2006，451，6： | 1 |
| 15 | Ligation of TLR9 induced on human IL-10-secreting Tregs by 1[alpha],25-dihydroxyvitamin D3 abrogates regulatory function显示文摘 | Urry Zo? Xystrakis Emmanuel Richards David F McDonald Joanne Sattar Zahid Cousins David J Corrigan Christopher J Hickman Emma Brown Zarin Hawrylowicz Catherine M | 2009 | Journal of Clinical Investigation2009，，2： | 1 |
| 16 | In situ study of soot from the combustion of a biomass pyrolysis intermediate-eugenol-and n-decane using aerosol time of flight mass spectrometry显示文摘 | TERESA B M JACQUELINE M W EMMA M F JENNY M J ALAN W | 2010 | Energy Fuels2010，24，1： | 1 |
| 17 | Genetic homogeneity but IgG subclass-dependent clinical variability of alloimmune membranous nephropathy with anti-neutral endopeptidase antibodies 显示文摘 | Vivarelli M Emma F Pelle T | 2015 | Kidney Int2015，87，3： | 1 |
| 18 | Broadening the spectrum of diseases related to podocin mutations 显示文摘 | Caridi G Bertelli R Di Duca M Dagnino M Emma F Onette Muda A | 2003 | J Am Soc Nephrol2003，14，5： | 1 |
| 19 | Genetic homogeneity but IgG subclass-dependent clinical variability of alloimmune membranous nephropathy with anti-neutral endopeptidase antibodies 显示文摘 | VIVARELLI M EMMA F PELLI T | 2015 | Kidney Int2015，87，3： | 1 |
| 20 | Eculizumab for the treatment of dense-deposit disease 显示文摘 | Vivarelli M Pasini A Emma F | 2012 | N Engl J Med2012，366，12： | 1 |
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