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| 1 | Serum positive cagA in patients with non-ulcer dyspepsia and peptic ulcer disease from two centers in different regions of Turkey显示文摘AIM: To investigate and compare frequencies of serum positive cagA in patients from two separate regions of Turkey who were grouped according to the presence of peptic ulcer disease or non-ulcer dyspepsia.METHODS: One hundred and eighty Helicobacter pyloripositive patients with peptic ulcer disease or non-ulcer dyspepsia were included in the study. One hundred and fourteen patients had non-ulcer dyspepsia and 66 had peptic ulcer disease (32 with gastric ulcers and/or erosions and 34with duodenal ulcers). Each patient was tested for serum antibody to H. pylori cagA protein by enzyme immunoassay.RESULTS: The total frequency of serum positive cagA in the study group was 97.2 %. The rates in the patients with peptic ulcers and in those with non-ulcer dyspepsia were 100% and 95.6%, respectively. These results were similar to those reported in Asian studies, but higher than those that have been noted in other studies from Turkey and Western countries.CONCLUSION: The high rates of serum positive cagA in these patients with peptic ulcer disease and non-ulcer dyspepsia were similar to results reported in Asia. The fact that there was high seroum prevalence regardless of ulcer status suggests that factors other than cagA might be responsible for ulceration or other types of severe pathology in H. pylori-positive individuals. | Ender Serin Uur Yilmaz Ganiye Künefeci Birol zer Yüksel Gümürdülü Mustafa Gülü Fazilet Kayaseluk Sedat Boyaciolu | 2003 | World Journal of Gastroenterology2003，9，4： | 10 |
| 2 | Partial virological response to three different nucleotide analogues in naive patients with chronic hepatitis B显示文摘BACKGROUND: The definition of partial virological response(PVR) was proposed because of its clinical relevance. PVR relates to subsequent therapeutic failure which results in the modification of the regimen. Whether this rationale can be applied to all nucleotide analogues (NA) is not clear. This study was undertaken to analyze PVR influence on therapeutic outcomes during lamivudine, entecavir or tenofovir mono therapy in NA-naive patients with chronic hepatitis B in routine clinical practice.METHODS: We retrospectively analyzed 150 NA-naive patients with chronic hepatitis B. These subjects received lamivudine entecavir or tenofovir monotherapy between February 2001 and July 2013.RESULTS: Sixty-nine patients were treated with lamivudine, 35with entecavir, and 46 with tenofovir. The median therapeutic duration was 19.5 (6-147) months. PVR rates at 24 weeks were similar among three NAs (lamivudine 33.3%, entecavir 35.0%tenofovir 32.4%, P=0.981). For all three NAs, patients with a higher baseline viral load or HBeA g-positive status had a higher serum viral positive rate tested by polymerase chain reaction at week 24 and 48. Cumulative probability of virological breakthrough (VBR) for patients treated with lamivudine was67% at 5 years, and PVR at 24 weeks was the independent risk factor for VBR (HR: 3.09; 95% CI: 1.09-8.74; P=0.034); also lamivudine treated patients older than 50 years seemed to have a tendency for VBR (HR: 2.80; 95% CI: 0.99-8.18; P=0.052)A majority of entecavir and tenofovir partial responders achieved and maintained virological response with prolonged monotherapy, except one entecavir treated patient who experienced VBR due to resistance mutations.CONCLUSIONS: Management strategy for lamivudine treatment should include adaptation of regimen according to PVR as an on-treatment response parameter due to its relation with unacceptably high VBR probability. Similar conclusion should not be directly related to entecavir or tenofovir treatment. | Ender G Yegin Osman Cavit Ozdogan | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，6： | 5 |
| 3 | Nitrogen dynamics following field application of biochar in a temperate North American maize-based production system显示文摘 | David Güere?a Johannes Lehmann Kelly Hanley Akio Enders Charles Hyland Susan Riha | 2013 | Plant and Soil2013，，1： | 2 |
| 4 | Evaluation of hepatoprotective effect of Gentiana olivieri herbs on subacute administration and isolation of active principle显示文摘 | Didem Deliorman Orhan Mustafa Aslan G?knur Aktay Ender Ergun Erdem Yesilada Fatma Ergun | 2003 | Life Sciences2003，，20： | 2 |
| 5 | Is There a Relationship Between Chronic Periodontitis and Erectile Dysfunction?显示文摘 | Fatih O?uz Abubekir Eltas Ali Beytur Ender Akdemir Mustafa ?zay Uslu Ali Güne? | 2012 | The Journal of Sexual Medicine2012，，3： | 1 |
| 6 | Space-time processing for multi-channel synthetic aperture radar 显示文摘 | Ender J H G | 1999 | Electronics & Communication Engineering Journal1999，11，1： | 1 |
| 7 | Current epidemiological aspects of human parvovirus B19 infection during pregnancy and childhood in the western part of Germany显示文摘 | Enders M Weidner A Enders G | 2007 | Epidemiol Infect2007，135，4： | 1 |
| 8 | Frequency of rheumatic diseases in patients with autoimmune thyroid disease显示文摘 | Mehmet S Sibel G Ender A | 2007 | Rheumatology Inter- national2007，2，7： | 1 |
| 9 | Space-time processing for multi channel synthetic aperture radar显示文摘 | Ender J H G | 1999 | Electronic Communication Engineering Jou- hal1999，11，1： | 1 |
| 10 | P-selectin mediates platelet-endothelial cell interactions and reperfusion injury in the mouse liver in vivo显示文摘 | Khandoga A Biberthaler P Enders G | 2002 | Shock2002，18，6： | 1 |
| 11 | Current epide- miological aspects of human parvovirus B19 infection dur- ing pregnancy and childhood in the western part of Ger- many 显示文摘 | ENDERS M WEIDNER A ENDERS G | 2007 | Epidemiol Infect2007，135，4： | 1 |
| 12 | Space-time Processing for Multichannel Synthetic Aperture Radar显示文摘 | Ender J H G | 1999 | Electronics and Communication Engineering Journal1999，11，1： | 1 |
| 13 | Wide-Area Traffic Monitoring With the SAR/GMTI System PAMIR 显示文摘 | Cerutti-Maori D Klare J Brenner A R and Ender J H G | 2008 | IEEE Transactions on Geoscience and Remote Sensing2008，46，10： | 1 |
| 14 | Elevated serum uric acid in nondiabetic people mark pro-inflammatory state and HDL dysfunction and independently predicts coronary disease显示文摘 | Altan Onat Günay Can Ender ?rnek Servet Altay Murat Yüksel Evin Ademo?lu | 2013 | Clinical Rheumatology2013，，： | 1 |
| 15 | Evaluation of a new enzyme immunoassay based on recombinant rubella virus-like particles for detection of immunoglobulin M antibodies to rubella virus 显示文摘 | Grangeot-Keros L Enders G | 1997 | J Clin Microbiol1997，35，2： | 1 |
| 16 | Sensitivity of a new commercial enzyme linked immunospot assay (T SPOT-TB) for diagnosis of tuberculosis in clin ical practice显示文摘 | Meier T Eulenbruch HP Wriqhton-Smith P Enders G Regnath T | 2005 | Eur J Clin Microbiol Infect Dis2005，24，8： | 1 |
| 17 | Outcome of confirmed periconceptional maternal rubella显示文摘 | Enders G Nickerl-Pacher U Miller E | | 0，，： | 1 |
| 18 | P - selectin medi- ates platelet - endothelial celt interactions and reperfusion inju- ry in the mouse liver in vivo 显示文摘 | Khandoga A Biberthaler P Enders G | 2002 | Shock2002，18，6： | 1 |
| 19 | Remifentanil with thiopental for tracheal intubation without muscle relaxants 显示文摘 | Durmus M Ender G Kadir BA | 2003 | Anesth Analg2003，96，5： | 1 |
| 20 | Demonstration of advanced reconnaissanse techniques with the airborne SAR/GMTI sensor PAMIR显示文摘 | Brenner A R Ender J H G | 2006 | IEE Proc Radar Sonar and Navigation2006，153，2： | 1 |
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