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	题名	作者	年代	出处	被引量
1	Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed.	Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost	2019	Stroke & Vascular Neurology2019，4，4：	2
2	Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000)显示文摘	Eng L F Ghirnikar R S Lee Y L	2000	Neurochem Res2000，25，910：	2
3	Physiology and path-ophysiology of the adipose tissue renin-angiotensin system显示文摘	Engeli S Negrel R Sharma A M	2000	Hypertension2000，35，6：	1
4	Architectural anlysis and intraoperative measurements demonstrate the unique design of the multifidus muscle for lumbar spine stability显示文摘	WARD S R KIM C W ENG C M		0，，01：	1
5	NOx Emissions Prom Flameless Coal Combustion in Air, Ar/O2 and CO2/O2 显示文摘	NO Emission During Oxy-Fuel Ind Eng Chem Res 2008 47(6): Hannes S Dragisa R	2009	Proceedings of the Combustion Institute2009，32，：	1
6	Inflammation in traumatic brain injury:role of cytokines and chemokines显示文摘	Lee Y L Eng L F	1998	Neurochem Res1998，23，3：	1
7	Glial fibrillary acidic protein:GFAP-thirty-one years(1969-2000)显示文摘	Eng L F Ghirnikar R S Lee Y L	2000	Neurochem Res2000，25，910：	1
8	Differential regu- lation of the expression of cytochrome P450 aromatase, estro- gen and androgen receptor subtypes in the brain- pituitary-o varian axis of the Japanese eel (Anguilla japonica ) reveals steroid dependent and independent mechanisms 显示文摘	J ENG S R PASQUIER J YUEH W S	2012	Gen Comp Endocrinol2012，175，1：	1
9	Chemokine antagonist infusion promotes axonal sparing after spinal cord contusion injury in rat显示文摘	Lee Y L Eng L F	2001	Neurosci Res2001，64，6：	1
10	Physiology and patho- physiology of the adipose tissue renin-angiotensin system 显示文摘	Engeli S Negrel R Sharma AM	2000	Hypertension2000，35，6：	1
11	Nicotinamide adenine dinueleotide fluorescence spectroscopy and imaging of isolated cardiac myoeytes显示文摘	ENG J LYNCH R M BALABAN R S	1989	Biophys J1989，55，4：	1
12	Evaluation of antimicrobial activities of Satureja hortensis L.显示文摘	F ?ahin ? Karaman M Güllüce H ??üt?ü M ?engül A Ad?güzel S ?ztürk R Kotan	2003	Journal of Ethnopharmacology2003，，1：	1
13	Use of D2 lactic acid measurement in the diagnosis of bacterial infections显示文摘	SMITH S M ENG R H K BUCCINI F	1986	J Infect Dis1986，154，：	1
14	Studies on untreated and urea-treated rice straw from three cultivation seasons: Histologi- cal investigations by light and scanning electron microscopy 显示文摘	Shen H S Sundstel F Eng E R	1999	Anim Feed Sci Tech1999，80，：	1
15	Glial fibrillary acidic protein:GFAP-thirty-one years (1969-2000)显示文摘	Eng L F Ghirnikar R S Lee Y L	2000	Neurochem Res2000，25，910：	1
16	Bactericidal effects of antibiotics on slowly growing and nongrowing bacteria显示文摘	Eng R H K Padberg F T Smith S M	1991	Antimicrobial Agents and Chemothercpy1991，，：	1
17	Inflammation in traumatic brain injury: role of cytokines and chemokines显示文摘	Ghirnikar R S Lee Y L Eng L F	1998	Neurochem Res1998，23，3：	1
18	Hepatic Yttrium -90 radio- embolotherapy in metastatic eolorectal eaneer treated with cetux- imab or bevacizumab显示文摘	Murthy R Eng C Krishnan S	2007	J Vasc Interv Radiol2007，18，12：	1
19	Use of D-lactic acid measurements in the diagnosis of bacterial infections显示文摘	Smith S M Eng R H Buccini F	1986	J Infect Dis1986，154，4：	1
20	Architectural analysis and intraoperative measurements demonstrate the unique design of the multifidus muscle for lumbar spine stability显示文摘	WARD S R KIM C W ENG C M	2009	J Bone Joint Surg Am2009，91，1：	1

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