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| 1 | Photodynamic therapy vs radiofrequency ablation for Barrett's dysplasia: Efficacy,safety and cost-comparison显示文摘AIM:To compare effectiveness,safety,and cost of photodynamic therapy(PDT)and radiofrequency ablation(RFA)in treatment of Barrett’s dysplasia(BD).METHODS:Consecutive case series of patients undergoing either PDT or RFA treatment at single center by a single investigator were compared.Thirty-three patients with high-grade dysplasia(HGD)had treatment with porfimer sodium photosensitzer and 630 nm laser(130 J/cm),with maximum of 3 treatment sessions.Fifty-three patients with BD(47 with low-grade dysplasia-LGD,6 with HGD)had step-wise circumferential and focal ablation using the HALO system with maximum of 4 treatment sessions.Both groups received proton pump inhibitors twice daily.Endoscopic biopsies were acquired at 2 and 12 mo after enrollment,with 4-quadrant biopsies every 1 cm of the original BE extent.A complete histological resolution response of BD(CR-D)was defined as all biopsies at the last endoscopy session negative for BD.Fisher’s exact test was used to assess differences between the two study groups for primary outcomes.For all outcomes,a two-sided P value of less than 0.05 was considered to indicate statistical significance.RESULTS:Thirty(91%)PDT patients and 39(74%)RFA were men(P=0.05).The mean age was 70.7±12.2 and 65.4±12.7(P=0.10)year and mean length of BE was 5.4±3.2 cm and 5.7±3.2 cm(P=0.53)for PDT and RFA patients,respectively.The CR-D was(18/33)54.5%with PDT vs(47/53)88.7%with RFA(P=0.001).One patient with PDT had an esophageal perforation and was managed with non-surgical measures and no perforation was seen with RFA.PDT was five times more costly than RFA at our institution.The two groups were not randomized and had different BD grading are the limitations of the study.CONCLUSION:In our experience,RFA had higher rate of CR-D without any serious adverse events and was less costly than PDT for endoscopic treatment of BD. | Atilla Ertan Irum Zaheer Arlene M Correa Nirav Thosani Shanda H Blackmon | 2013 | World Journal of Gastroenterology2013，19，41： | 7 |
| 2 | 老年男性勃起功能及迟发性性腺功能减退症状与下尿路症状严重性的关系显示文摘本文旨在研究土耳其爱琴海地区的老年男性下尿路症状(LUTSs)、勃起功能障碍(ED)和有症状的迟发性性腺功能减退症(SLOH)三者间的关系。符合以下标准的500名男性患者被纳入该研究:40周岁以上;过去6个月内有稳定的性关系;在六个泌尿外科诊所之一进行过就诊登记。每位患者均行血清PSA、睾酮水平及尿流率的检测,并填写国际前列腺症状评分和生活质量评分(IPSS-QoL)量表、国际勃起功能指数(IIEF)问卷和老年男性症状(AMS)量表。在所有的研究对象中,23.9%的患者有轻度LUTSs,53.3%有中度LUTSS,22.8%有重度LUTSS。每组间总睾酮水平无明显差异。除此之外,69.6%的病人患有ED,且ED的发生率与LUTS严重性呈正相关。71.2%的患者出现SLOH(AMS〉27),且IPSS评分越高,严重的性腺功能减退症状的发生率也越高。相关性分析显示以上三种问卷分数之间有显著关联。总之,LUTS严重性是ED和SLOH的非年龄依赖性危险因素,LUTS严重性和SLOH症状之间似乎有显著的相关性,但还需要从病因学和生物学角度进行深入阐明。 | Ozan Bozkurt Deniz Bolat Omer Demir Oktay Ucer Ali Sahin Burak Ozcift Abdulkadir Pekta Tahir Turan Bilal H Gümü Ertan Cans Ahmet Bolukbasi Haluk Erol Adil Esenx | 2013 | Asian Journal of Andrology2013，15，6： | 4 |
| 3 | Atonomous wind energy conversion system with a simple controller for maximum-power transfer 显示文摘 | Ermis A Ertan M Akpinar H B | 1992 | Electric Power Applications IEE Proceedings B1992，139，5： | 2 |
| 4 | Powder metaldevelopment for electrical motor applications 显示文摘 | BAYRAMLI E OLGEUOGLU O ERTAN H B | 2005 | Journal ofMaterials Processing Technology2005，161，12： | 1 |
| 5 | Second de- rivative spectrophotometric determination o{ p-amino- phenol in the presence of paracetamol 显示文摘 | YESILADA A ERDOGAN H ERTAN M | 1991 | Analy Lett1991，24，1： | 1 |
| 6 | Extended release lipophilic indomethacin microspheres:formulation factors and mathematical equations fitted drug release rates显示文摘 | KARASULU E YESIM KARASULU H ERTAN G | 2003 | Eur J Pharm Sci2003，19，23： | 1 |
| 7 | Factors influencing flap and INTACS deeen- tration after femtosecond laser application in normal and keratocon- ic eyes显示文摘 | Ertan A Karacal H | 2008 | J Refract Surg2008，24，： | 1 |
| 8 | Factors influencing flap and INTACS decentration after femtosecond laser application in normal and keratoconic eyes 显示文摘 | Ertan A Karacal H | 2008 | J Refract Surg2008，24，8： | 1 |
| 9 | Stabilization of Escherichia coli penicillin G acylase against thermal inactivation by cross-linking with dextran dialdehyde polymer显示文摘 | KAZAN D ERTAN H ERARSLAN A | 1997 | Appl Mieroblol Bioteehnol1997，48，2： | 1 |
| 10 | Activation patterns in forearm muscles during archery shooting显示文摘 | H ERTAN B KENTEL | 2003 | Human Movement Sci2003，，22： | 1 |
| 11 | Biotechnological uses of enzymes from psychrophiles显示文摘 | Cavicehioli R Charlton T Ertan H | 2011 | Microbial Biotechnology2011，4，4： | 1 |
| 12 | Some properties of glutamate dehydrogenase, glutamine synthetase and glutamate syntyase from ynebacterium callume 显示文摘 | Ertan H | 1992 | Arch Microbiol1992，158，： | 1 |
| 13 | Carbon and nitrogen substrate utilization in the marine bacterium Sphingopyxis alaskensis strain RB2256显示文摘 | Williams T J Ertan H Ting L | 2009 | ISME Journal2009，3，9： | 1 |
| 14 | Multimodal Wireless Sensor Network-Based Ambient Assisted Living in Real Homes with Multiple Residents显示文摘 | Tunca C Alemdar H Ertan H | 2014 | Sensors2014，14，6： | 1 |
| 15 | Powder metal deve- lopment for electrical motor applications 显示文摘 | Byramli E Olgelioglu O Ertan H B | 2005 | J Mater Process Techn2005，161，12： | 1 |
| 16 | Biotechnological u-ses of enzymes from psychrophiles 显示文摘 | Cavicchioli R Charlton T Ertan H | 2011 | Microbial Biotechnolo-gy2011，4，44： | 1 |
| 17 | Release and diffusional modeling of metronidazole lipid matrices 显示文摘 | Ozyazici M Gokce E H Ertan G | 2006 | Eur J Pharm Biopharm2006，63，3： | 1 |
| 18 | ACE gene polymorphism and renal scarring in children with vesicouretheral reflux显示文摘 | Erdogan H Ertan P Ozkayin N | 2003 | BANTAO J2003，2，1： | 1 |
| 19 | Autonomous wind energy conversion system with a simple controller for maximum power transfer显示文摘 | ERMIS M ERTAN H B AKPINAR E | 1992 | IEE Proceedings B of Electric power applications1992，139，5： | 1 |
| 20 | Quantification the relationship between FIFA scores and EMG skill indexes in archery显示文摘 | H ERTAN A R SOYLU F KORKUSUZ | 2005 | J Eleetromyography Kinesiology2005，，22： | 1 |
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