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| 1 | The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition显示文摘在人的不孕病人的精子在场的最普通的损害之一是精子鸡蛋识别的自发的失败。尽管这个唯一的细胞的相互作用现在能被象 intracytoplasmic 精子注射(ICSI ) 那样的帮助繁殖策略乐意地绕过,最近的大规模流行病学的研究鼓励了这种技术的小心的使用并且为对为有缺点的精子鸡蛋识别负责的机制的进一步的研究加亮需要。这个领域里的以前的工作证实了为卵母细胞相互作用负责的精子领域在动态地在女繁殖的道在 epididymal 成熟和 capacitation 期间被修改以前在精子发生期间被形成。当为这些顺序的 maturational 事件的规定负责的因素无疑是复杂的时,新兴的研究识别了分子的女伴,加热吃惊蛋白质 A2 (HSPA2 ) ,,在人的精子的这些事件的一个关键管理者。HSPA2 是支持合拢,运输,和集会蛋白质建筑群的 70 kDa 热吃惊蛋白质家庭的一个充实睾丸的成员并且断然被相关与在 vitro 授精(IVF ) 成功。而且,从人的精子 proteome 减少了 HSPA2 的表示为跟随 IVF 和 ICSI 的积云矩阵疏开,精子鸡蛋识别和授精导致一个损害能力。在这评论,我们考虑在精子功能支持 HSPA2 的角色的证据并且探索它被在不肥沃的病人的精子弄空的潜在的机制。进管理精子的分子的机制的如此的信息提议小说卓见工作。 | Brett Nixon Elizabeth G Bromfield Matthew D Dun Kate A Redgrove Eileen A McLaughlin R John Aitken | 2015 | Asian Journal of Andrology2015，17，4： | 8 |
| 2 | Intrahepatic Cholangiocarcinoma: Rising Frequency, Improved Survival, and Determinants of Outcome After Resection显示文摘 | Itaru Endo Mithat Gonen Adam C. Yopp Kimberly M. Dalal Qin Zhou David Klimstra Michael D?Angelica Ronald P. DeMatteo Yuman Fong Lawrence Schwartz Nancy Kemeny Eileen O?Reilly Ghassan K. Abou-Alfa Hiroshi Shimada Leslie H. Blumgart William R. Jarnagin | 2008 | Annals of Surgery2008，，1： | 1 |
| 3 | O6 - Benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial Rat Glioma 显示文摘 | Laurence D Rhines Prakash Sampath Eileen Dolan M | 2000 | Cancer Research2000，60，： | 1 |
| 4 | Effects of distribution-based parameter aggregation on a spatially distributed agricultural nonpoint source pollution model显示文摘 | Eileen C Mackay D S | 2004 | J Hydrology2004，295，： | 1 |
| 5 | Failure Patterns in Resected Pancreas Adenocarcinoma: Lack of Predicted Benefit to SMAD4 Expression显示文摘 | Jordan M. Winter Laura H. Tang David S. Klimstra Weiguo Liu Irena Linkov Murray F. Brennan Michael I. D?Angelica Ronald P. DeMatteo Yuman Fong William R. Jarnagin Eileen M. O?Reilly Peter J. Allen | 2013 | Annals of Surgery2013，，2： | 1 |
| 6 | A modified quantitative subj-ective global assessment(MQSGA) of nutrition for dialysis patients显示文摘 | Kamyar KZ Morton K Eileen D | 1999 | Nephrol Dial Transplant1999，14，7： | 1 |
| 7 | Isolation of total cellular RNA from brain tissue 显示文摘 | Eileen D W Gilby K L Howlett S E | 2001 | Practical Approach Series2001，10，： | 1 |
| 8 | A Cost-Effectiveness Analysis of Alternative Disease Management Strategies in Patients with Crohn's Disease Treated with Azathioprine or 6 Mercaptopurine显示文摘 | Maria C D Eileen R Joshua O | 2005 | The A- merican Journal of Gastroenterology2005，100，： | 1 |
| 9 | A modified quantitative subjective global assessment of nutrition for dialysis patients显示文摘 | Kamyar KZ Morton K Eileen D | 1999 | Nephrol Dial Transplant1999，14，7： | 1 |
| 10 | Effects of distribution- based parameter aggregation on a spatially distributed agricultural nonpoint source pollution model显示文摘 | Chen Eileen Mackay D Scott | 2004 | Journal of Hydrology2004，，295： | 1 |
| 11 | Estimation of EOF expansion coefficients for incomplete data显示文摘 | Janice D B Eileen P K Pavel P | 1994 | Deep Sea Research Part I: Oceanographic Research Papers1994，41，： | 1 |
| 12 | A modified quantitative subjective global assessment of nutrition for dialysis patients 显示文摘 | Kamyar K Z Morton K Eileen D | 1999 | Nephrol Dial Transplant1999，14，： | 1 |
| 13 | In vivo generation of human dendritic cell subsets by Flt3 ligand显示文摘 | Eugene M Elizabeth D Eileen R | 2000 | Blood2000，96，3： | 1 |
| 14 | Discovery of single nu- cleotide polymorphisms in lycopersicon esculentum by computer aided analysis of expressed sequence tags 显示文摘 | Yang W C Bai X D Eileen K | 2004 | Molecular Breed- ing2004，14，： | 1 |
| 15 | Effects of distribution-based parameter aggregation on a spatially distributed agricultural nonpoint source pollution model显示文摘 | Eileen Chen Scott Mackay D | 2004 | Journal of Hydrology2004，295，： | 1 |
| 16 | O6-Benzylguanine Potentiates the Antitumor Effect of Locally Delivered Carmustine against an Intracranial Rat Glioma显示文摘 | Laurence D Rhines Prakash Sampath Eileen Dolan M | 2000 | Cancer Research2000，60，： | 1 |
| 17 | Ambulatory blood pressure monitoring and interdialytic weight gain in children receiving haemodialysis显示文摘 | Sorof JM Eileen D Brewer MD | 1999 | Am J Kidney Dis1999，33，4： | 1 |
| 18 | A Biomathematical Model of Particle Clearance and Retention in the Lungs of Coal Miners 显示文摘 | Eileen D Kuempel | 2001 | Regulatory Toxicology and Pharmacology2001，，34： | 1 |
| 19 | Discovery of single nuc-leotide polymorphisms in lycopersicon esculentum by comput-er aided analy- sis of expressed sequence tags显示文摘 | Yang W C Bai X D Eileen K | 2004 | Molecular Breeding2004，14，1： | 1 |
| 20 | 显示文摘 | Agnes R D Eileen B S | 2001 | J Appl Polym Sci2001，81，： | 1 |
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