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3篇 您的检索式:作者名="Elizabeth Bird"
    题名 作者 年代 出处 被引量
1Pooled Analyses of Effects on C-Reactive Protein and Low Density Lipoprotein Cholesterol in Placebo-Controlled Trials of Ezetimibe Monotherapy or Ezetimibe Added to Baseline Statin Therapy显示文摘Thomas A. Pearson Christie M. Ballantyne Enrico Veltri Arvind Shah Steven Bird Jianxin Lin Elizabeth Rosenberg Andrew M. Tershakovec 2009The American Journal of Cardiology2009,,3:1
2Population-Based Study Reveals New Risk-Stratification Biomarker Panel for Barrett’s Esophagus显示文摘Elizabeth L. Bird–Lieberman Jason M. Dunn Helen G. Coleman Pierre Lao–Sirieix Dahmane Oukrif Christina E. Moore Sibu Varghese Brian T. Johnston Kenneth Arthur Damian T. McManus Marco R. Novelli Maria O’Donovan Christopher R. Cardwell Laurence B. Lovat Lia 2012Gastroenterology2012,,4:1
3Induction of resistance vessel dilation by ginger root juice,possibly through extracellular signal-regulated kinase 1/2 and endothelial nitric oxide synthase activation in endothelial cells显示文摘Objective:To investigate the effects of ginger root juice on contractibility of resistance blood vessels from mice and on activation of extracellular signal-regulated kinase 1/2(ERK1/2)and endothelial nitric oxide synthase(eNOS)in human endothelial cells.Methods:Juice was prepared from semi-dry ginger roots.Mesenteric artery rings were dis-sected from healthy adult C57BL/J6 mice.Primary human umbilical vein endothelial cells(HU-VECs)were isolated from umbilical cords of normal full-term babies.The contractibility of the dissected vessel rings in the presence or absence of ginger root juice at 0.1%(v/v)after potassium(100 mM KCL)stimulation was measured by wire myography.The phosphorylation levels of ERK1/2 and eNOS in the presence of ginger root juice in the culture medium at 0,0.025%,0.05%,0.1%,and 0.2%(v/v)in HUVECs were assessed by western blotting analysis.Results:An immediate sharp increase in the contractile activity was observed in mesenteric artery rings in response to KCL stimulation.Ginger root juice effectively attenuated the KCL-mediated vessel contraction.Moreover,ginger root juice significantly increased phosphorylation of ERK1/2 and eNOS in a dose-dependent manner.Conclusions:Ginger root juice is capable of relaxing resistance blood vessels.Activation of ERK1/2 and eNOS through phosphorylation in endothelial cells may be a mechanism underlying the vasodilator activity of ginger root.Elizabeth Bird Dinesh M.Shah 2013Family Medicine and Community Health2013,1,3:0
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