|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation显示文摘 | D.L Lacey E Timms H.-L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.-X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle | 1998 | Cell1998，，2： | 4 |
| 3 | Fractionation of polyethylene显示文摘 | FRSNCIS P S COOKE R C Jr ELLIOTT J H | 1958 | J Polym Sci1958，31，123： | 1 |
| 4 | A review of sharps injures and preventitire strategies显示文摘 | Trim J C Elliott T S J | 2003 | J Hospit Inf2003，53，： | 1 |
| 5 | Identification and quantification of amines in the equine caecum显示文摘 | BAILEY S R MARR C M ELLIOTT J | 2003 | Research in Veterinary Science2003，74，2： | 1 |
| 6 | Screening and confirmatory determination of ractopamineresidues in calves treated with growth promoting doses of theβ-agonist显示文摘 | Elliott C Thompson C Crooks S H | 1998 | Analyst1998，123，5： | 1 |
| 7 | A Review of Sharps Injures and Preventative Strategies显示文摘 | Trim J C Elliott T S J | 2003 | Journal of Hospital Infection2003，53，4： | 1 |
| 8 | Goals:An approach to motivation and achievement显示文摘 | Elliott E S Dweek C s | 1998 | Joumal of Personality mad Social psychology1998，54，1： | 1 |
| 9 | The ecological basis for simula-ting phytoplankton responses to environmental change(PROTECH)显示文摘 | Reynolds C S Irish A E Elliott J A | | 0，，03： | 1 |
| 10 | Replication of genome-wide association sig- nals in UK samples reveals risk loci for type 2 diabetes显示文摘 | Zeggini E Weeclon M N Lindgren C M Frayling T M Elliott K S Lango H | 2007 | Sci- ence2007，316，： | 1 |
| 11 | Goals : An Approach to Motivation and Achievement显示文摘 | Elliott E S Dweck C S | 1988 | Journal of Personality and Social Psychology1988，54，1： | 1 |
| 12 | Ex utero intrapartum treat- ment procedure for management of congenital high airway obstruction syndrome in a vertex/breech twin gestation显示文摘 | Elliott R Vallera C Heitmiller E S | 2013 | Int J Pediatr Otorhi- nalaryngo12013，77，3： | 1 |
| 13 | Light-induced oxidation and band-edge shifts in thermally evaporated films of germanium chalcogenide glasses 显示文摘 | SPENCE C A ELLIOTT S R | 1989 | Phys Rev B1989，39，8： | 1 |
| 14 | A finite element model for the time-dependent joule heating problem 显示文摘 | Elliott C M Larsson S | 1995 | Comput Appl Math1995，64，212： | 1 |
| 15 | Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by o steoprotegerin l igand显示文摘 | Hsu H Lacey DL Dunstan CR Solovyev I Colombero A Timms E Tan HL Elliott G Kelley MJ Sarosi I Wang L Xia XZ Elliott R Chiu L Black T Scully S Capparelli C Morony S Shimamoto G Bass MB Boyle WJ | | 0，，： | 1 |
| 16 | Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy显示文摘 | PARENT J M ELLIOTT R C PLEASURE S J | 2006 | Ann Neurol2006，59，1： | 1 |
| 17 | Effects of varespladib methyl on biomarkers and major cardiovascular events in acute coronary syndrome patients 显示文摘 | Rosenson R S Hislop C Elliott M | 2010 | J Am Coll Cardiol2010，56，14： | 1 |
| 18 | Repeatability of upper limb kinematics for children with and without cerebral palsy 显示文摘 | Reid S Elliott C Alderson J | 2010 | Gait Posture2010，32，1： | 1 |
| 19 | Synchrotron X-ray raicrotomographic investigation of mineral concentrations at rrficrometre scale in sound and carious enamel 显示文摘 | S E P Dowker J C Elliott G R Davis | 2004 | Caries Res2004，38，6： | 1 |
| 20 | Dispersion of salt and suspended sediment in a partly mixed estuary显示文摘 | Uncles R J Elliott R C A Weston S A | 1985 | Estuaries1985，8，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员