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| 1 | Portal vein thrombosis:Insight into physiopathology,diagnosis,and treatment显示文摘Portal vein thrombosis (PVT) is a relatively common complication in patients with liver cirrhosis, but might also occur in absence of an overt liver disease. Several causes, either local or systemic, might play an important role in PVT pathogenesis. Frequently, more than one risk factor could be identified; however, occasionally no single factor is discernable. Clinical examination, laboratory investigations, and imaging are helpful to provide a quick diagnosis, as prompt treatment might greatly affect a patient's outcome. In this review, we analyze the physiopathological mechanisms of PVT development, together with the hemodynamic and functional alterations related to this condition. Moreover, we describe the principal factors most frequently involved in PVT development and the recent knowledge concerning diagnostic and therapeutic procedures. Finally, we analyze the implications of PVT in the setting of liver transplantation and its possible influence on patients' future prognoses. | Francesca R Ponziani Maria A Zocco Chiara Campanale Emanuele Rinninella Annalisa Tortora Luca Di Maurizio Giuseppe Bombardieri Raimondo De Cristofaro Anna M De Gaetano Raffaele Landolfi Antonio Gasbarrini | 2010 | World Journal of Gastroenterology2010，16，2： | 75 |
| 2 | Capsule endoscopy in pediatrics: A 10-years journey显示文摘Video capsule endoscopy(CE) for evaluation the esophagus(ECE), small bowel(SBCE) and the colon(CCE) is particularly useful in pediatrics, because this imaging modality does not require ionizing radiation, deep sedation or general anesthesia. The risk of capsule retention appears to be dependent on indication rather than age and parallels the adult experience by indication, making SBCE a relatively safe procedure with a significant diagnostic yield. The newest indication, assessment of mucosal change, greatly enhances and expands its potential benefit. The diagnostic role of CE extends beyond the SB. The use of ECE also may enhance our knowledge of esophageal disease and assist patient care. Colon CCE is a novel minimally invasive and painless endoscopic technique allowing exploration of the colon without need for sedation, rectal intubation and gas insufflation. The limited data on ECE and CCE in pediatrics does not yet allow the same conclusions regarding efficacy; however, both appear to provide safe methods to assess and monitor mucosal change in their respective areas with little discomfort. Moreover, although experience has been limited, the patency capsule may help lessen the potential of capsule retention; and newly researched protocols for bowel cleaning may further enhance CE's diagnostic yield. However, further research is needed to optimize the use of the various CE procedures in pediatric populations. | Salvatore Oliva Stanley A Cohen Giovanni Di Nardo Gianfranco Gualdi Salvatore Cucchiara Emanuele Casciani | 2014 | World Journal of Gastroenterology2014，20，44： | 6 |
| 3 | Use of a combination strategy to improve neuroprotection and neuroregeneration in a rat model of acute spinal cord injury显示文摘Spinal cord injury is a very common pathological event that has devastating functional consequences in patients. In recent years, several research groups are trying to find an effective therapy that could be applied in clinical practice. In this study, we analyzed the combination of different strategies as a potential therapy for spinal cord injury. Immunization with neural derived peptides(INDP), inhibition of glial scar formation(dipyridyl: DPY), as well as the use of biocompatible matrix(fibrin glue: FG) impregnated with bone marrow mesenchymal stem cells(MSCs) were combined and then its beneficial effects were evaluated in the induction of neuroprotection and neuroregeneration after acute SCI. Sprague-Dawley female rats were subjected to a moderate spinal cord injury and then randomly allocated into five groups: 1) phosphate buffered saline; 2) DPY; 3) INDP + DPY; 4) DPY+ FG; 5) INDP + DPY + FG + MSCs. In all rats, intervention was performed 72 hours after spinal cord injury. Locomotor and sensibility recovery was assessed in all rats. At 60 days after treatment, histological examinations of the spinal cord(hematoxylin-eosin and Bielschowsky staining) were performed. Our results showed that the combination therapy(DPY+ INDP + FG+ MSCs) was the best strategy to promote motor and sensibility recovery. In addition, significant increases in tissue preservation and axonal density were observed in the combination therapy group. Findings from this study suggest that the combination theapy(DPY+ INDP + FG + MSCs) exhibits potential effects on the protection and regeneration of neural tissue after acute spinal cord injury. All procedures were approved by the Animal Bioethics and Welfare Committee(approval No. 178544; CSNBTBIBAJ 090812960)on August 15, 2016. | Elisa García Roxana Rodríguez-Barrera Vinnitsa Buzoianu-Anguiano Adrian Flores-Romero Emanuel Malagón-Axotla Marco Guerrero-Godinez Estefanía De la Cruz-Castillo Laura Castillo-Carvajal Monserrat Rivas-Gonzalez Paola Santiago-Tovar Ivis Morales Cesar Borlongan Antonio Ibarra | 2019 | Neural Regeneration Research2019，14，6： | 6 |
| 4 | Reduced epidermal growth factor expression in hypohidrotic ectodermal dysplasia and tabby mice 显示文摘 | Emanuelle Fantino Carlos George-Nascimento | 1996 | J Clin Lavest1996，97，： | 1 |
| 5 | A genetic etiology for a DiGeorge syndrome:comistent deletions and mi-crodeletions of 22q11显示文摘 | Driscoll D A Budarf M L Emanuel B S | 1992 | The American Journal of Human Genetics1992，50，： | 1 |
| 6 | Chronic rhinosinusitis:allergy and sinus computed tomography relationships显示文摘 | Emanuel I A shah S B | 2000 | Otolaryngol Head Neck Surg2000，123，6： | 1 |
| 7 | Bank predication:an investigation of cash flow based models 显示文摘 | Aziz Emanuel A D Lawson G | 1998 | Journal of Management Studies1998，，25： | 1 |
| 8 | A search of the missing carbon sink:a model of terrestrial biospheric response to landuse change and atmospheric CO2显示文摘 | King A W Emanuel W R Wullschleger S D and Post W M | 1995 | Tellus1995，47，： | 1 |
| 9 | Bank prediction:an investigation of cash flow based models显示文摘 | EMANUEL D LAWSON G | 1988 | Journal of Management Studies1988，，25： | 1 |
| 10 | Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-XS and activation of caspase-3 显示文摘 | Emanuele S Calvaruso G Lauricella M Giuliano M Bellavia GD Anneo A | 2002 | Int J Oncol2002，21，4： | 1 |
| 11 | Sensitivity of tropical cyclones to surface exchange coef- ficients and a revised steady-state model incorporating eye dynamics 显示文摘 | Emanuel K A | 1995 | J Atmos Sci1995，52，： | 1 |
| 12 | Projecting future concentrations of atmospheric CO2 with global carbon cycle models:the importance of simulating historical changes显示文摘 | King A W Emanuel W R Post W M | 1992 | Environment management1992，16，： | 1 |
| 13 | Thermodynamic control of hurricane intensity显示文摘 | Emanuel K A | 1999 | Nature1999，401，2： | 1 |
| 14 | Increasing destructiveness of tropical cyclones over the past 30 years显示文摘 | EMANUEL K A | 2005 | Nature2005，436，： | 1 |
| 15 | The maximum intensity of hurricanes显示文摘 | Emanuel K A | 1988 | Atmos Sci1988，54，： | 1 |
| 16 | Increasing destructiveness of tropical cyclones over the past 30 years 显示文摘 | EMANUEL K A | 2005 | Nature2005，，436： | 1 |
| 17 | Evaluation of Single Point Measuurement Method for Harmonic Pollution Cost Allocation显示文摘 | Davis E J Emanuel A E Pileggi D J | 2000 | IEEE Trans on Power Delivery2000，15，1： | 1 |
| 18 | An acoustic pyrometer system for tomographic thermal imaging in power plant boilers显示文摘 | Mauro B Emanuele A Salerno | 1996 | IEEE Transactions on Instrumentation and Measurement1996，45，1： | 1 |
| 19 | Some aspects of hurricane inner-core dy- namics and energetics 显示文摘 | Emanuel K A | 1997 | JoI/1Tlal of the Atmospheric Sciences1997，54，8： | 1 |
| 20 | Correlation clustering in general weighted graphs显示文摘 | DEMAINE E D EMANUEL D FIAT A IMMORLICA N | 2006 | Theoretical Computer Science2006，36，1： | 1 |
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