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| 1 | Search for a dark photon in the π 0 → e + e ? γ decay显示文摘 | P. Adlarson W. Augustyniak W. Bardan M. Bashkanov F.S. Bergmann M. Ber?owski H. Bhatt A. Bondar M. Büscher H. Calén I. Ciepa? H. Clement D. Coderre E. Czerwiński K. Demmich E. Doroshkevich R. Engels W. Erven W. Eyrich P. Fedorets K. F?hl K. Fransson F. Go | 2013 | Physics Letters B . 2013 (1-3)2013，，1： | 3 |
| 2 | Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome:A multicenter retrospective study显示文摘BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bowel syndrome(IBS).AIM To assess the association of HTR3 polymorphisms with depressive,anxiety,and somatization symptoms in individuals with IBS.METHODS In this retrospective study,623 participants with IBS were recruited from five specialty centers in Germany,Sweden,the United States,the United Kingdom,and Ireland.Depressive,anxiety,and somatization symptoms and sociodemographic characteristics were collected.Four functional SNPs—HTR3A c.-42C>T,HTR3B c.386A>C,HTR3C c.489C>A,and HTR3E c.*76G>A—were genotyped and analyzed using the dominant and recessive models.We also performed separate analyses for sex and IBS subtypes.SNP scores were calculated as the number of minor alleles of the SNPs above.The impact of HTR3C c.489C>A was tested by radioligand-binding and calcium influx assays.RESULTS Depressive and anxiety symptoms significantly worsened with increasing numbers of minor HTR3C c.489C>A alleles in the dominant model(F_(depressive)=7.475,P_(depressive)=0.006;F_(anxiety)=6.535,P_(anxiety)=0.011).A higher SNP score(range 0-6)was linked to a worsened depressive symptoms score(F=7.710,P-linear trend=0.006)in IBS.The potential relevance of the HTR3C SNP was corroborated,showing changes in the expression level of 5-HT3AC variant receptors.CONCLUSION We have provided the first evidence that HTR3C c.489C>A is involved in depressive and anxiety symptoms in individuals with IBS.The SNP score indicated that an increasing number of minor alleles is linked to the worsening of depressive symptoms in IBS. | Sabrina Berens Yuanjun Dong Nikola Fritz Jutta Walstab Mauro D'Amato Tenghao Zheng Verena Wahl Felix Boekstegers Justo Lorenzo Bermejo Cristina Martinez Stefanie Schmitteckert Egbert Clevers Felicitas Engel Annika Gauss Wolfgang Herzog Robin Spiller Miriam Goebel-Stengel Hubert Mönnikes Viola Andresen Frieling Thomas Jutta Keller Christian Pehl Christoph Stein-Thöringer Gerard Clarke Timothy G Dinan Eamonn M Quigley Gregory Sayuk Magnus Simrén Jonas Tesarz Gudrun Rappold Lukas van Oudenhove Rainer Schaefert Beate Niesler | 2022 | World Journal of Gastroenterology2022，28，21： | 2 |
| 3 | Comparison of the modular multilevel DC converter and the dual-active bridge converter for power conversion in HVDC and MVDC grids 显示文摘 | ENGELS P STIENEKER M SOLTAU N | 2015 | IEEE Transactions on Power Electronics2015，30，1： | 1 |
| 4 | Colonization and immu-nomodulation by Lactobacillus reuteri ATCC 55730 in the human gas-trointestinal tract显示文摘 | VALEUR N ENGEL P CARBAJAL N | 2004 | Appl Environ Microbiol2004，70，2： | 1 |
| 5 | Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting显示文摘 | Nagy N Legendre H Engels O | 2003 | Cancer2003，97，8： | 1 |
| 6 | Colonization and immuno-modulation by Lactobacillus reuteri ATCC 55730 in the human gastrointestinal tract显示文摘 | YALEUR N ENGEL P CARBAJAL N | 2004 | Appl Environ Microbiol2004，70，2： | 1 |
| 7 | H4stogenesis of giant cell tumors 显示文摘 | Wuelling M Engels C Jesse N | 2002 | Pathologe2002，23，5： | 1 |
| 8 | Abiotic synthesis of amino acids under hydrothermal conditions and the or- igin of life~a perpetual phenomenon显示文摘 | HENNET R J HOLM N G ENGEL M H | 1992 | Natur Wiss1992，79，8： | 1 |
| 9 | Experience with the molten-salt reactor experiment显示文摘 | Haubenreich P N Engel J R | 1970 | Nuclear Applications and Technology1970，8，： | 1 |
| 10 | Serum procalcitonin as a marker of post-cardiac arrest syndrome and long-term neurological recovery,but not of early-onset infections,in comatose post-anoxic patients treated with therapeutic hypothermia显示文摘 | ENGEL H HAMOUDA N B PORTMANN K | 2013 | Resuscitation2013，84，6： | 1 |
| 11 | The environmental and cost benefits of using diamond wire for quarrying and processing of natural stone显示文摘 | WRIGHT D N ENGELS J A | 2003 | Industrial Diamond Review2003，，4： | 1 |
| 12 | Cbanges of cerebral biood flow during the secondary expansion of a cortical contusion assessed by 14C- iodoantiphrine in mice using a non-invaaive protocol显示文摘 | Engel D C Mies G Terpolilli N A | 2008 | Neurotrauma2008，25，7： | 1 |
| 13 | Induction of TNF in human alveolar macrophages as a potential evasion mechanism of virulent Mycobacterium tuberculosis显示文摘 | Engele M E Stobetael K Castiglione N | 2006 | J Immun2006，172，： | 1 |
| 14 | Functional and evolutionary insights into the simple yet specific gut microbiota of the honey bee from metagenomic analysis显示文摘 | Engel P Moran N A | 2013 | Gut Microbes2013，4，1： | 1 |
| 15 | Comparison of the modular multilevel DC converter and the dual-active bridge converter for power conversion in HVDC and MVDC grids显示文摘 | Engel S Stieneker M Soltau N | 2015 | IEEE Transactions on PowerElectronics2015，30，1： | 1 |
| 16 | Daily and Compulsive Internet Use and Well-Being in Adolescence: A Diathesis-Stress Model Based on Big Five Personality Traits 显示文摘 | van der Aa N Overbeek G Engels R C M E | 2009 | Journal of Youth and Adolescence2009，38，6： | 1 |
| 17 | Phase transitions of ammonium nitrate doped with alkali nitrates studies with fast X-ray diffraction 显示文摘 | Deimling A Engel W Eisenreich N | 1992 | European symposium on the annual analysis and calorimetry1992，38，4： | 1 |
| 18 | Refined prognostic evaluation in colon carcinoma using immunohistochemicalgalectin fingerprinting显示文摘 | Nagy N Legendre H Engels O | 2003 | Cancer2003，97，8： | 1 |
| 19 | Regulation of phospholipase C activation by the number of H(2) receptors during Ca(2+)-induced differentiation of mouse keratinocytes 显示文摘 | Fitzsimons C Engel N Policastro L | 2002 | Biochem Pharmacol2002，63，10： | 1 |
| 20 | Histogenesis of giant cell tumors显示文摘 | Wuelling M Engels C Jesse N | 2002 | Pathologe2002，23，5： | 1 |
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