|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Forced arterial suction thrombec- tomy with the penumbra reperfusion catheter in acute basilar artery occlusion: a retro retro-spective comparison study in 2 Korean uni- versity hospitals显示文摘 | Eom YI Hwang YH Hong J | 2014 | AJNR Am J Neuroradiol2014，35，： | 1 |
| 2 | Identification and characterization of C106R, a novel mutation in the DNA-binding domain of GCMB, in a family with autosomal-dominant hypoparathyroidism 显示文摘 | Yi HS Eom YS Park leB | 2012 | Clin Endocrinol (Oxf)2012，76，5： | 1 |
| 3 | RHEB expression in fibroadenomas of the breast显示文摘 | Eom M Han A Yi SY | 2008 | Pathol Int2008，58，4： | 1 |
| 4 | Disturbance observer-based robust control for underwater robotic systems with passive joints显示文摘 | Chung G B Eom K S Yi B J | 2001 | Advanced Robotics2001，15，5： | 1 |
| 5 | Identification and characterization of CI06R, a novel mutation in the DNA-binding domain of GCMB, in a family with autosomal-dominant hypoparathyroidism显示文摘 | Yi H S Eom Y S Park leB | 2012 | Clin Endo-crinol (Oxf)2012，76，5： | 1 |
| 6 | Identification and characterization of C106R, a novel mutation in the DNA-binding domain of GCMB, in a family with autosomal-dominat hypoparathyroidism显示文摘 | Yi HS Eom YS Park leB | | Clin Endocrinol (Oxf)0，76，5： | 1 |
| 7 | Generation of double knockout cattle via CRISPR-Cas9 ribonucleoprotein(RNP)electroporation显示文摘Background Genome editing has been considered as powerful tool in agricultural fields.However,genome editing progress in cattle has not been fast as in other mammal species,for some disadvantages including long gestational periods,single pregnancy,and high raising cost.Furthermore,technically demanding methods such as microinjection and somatic cell nuclear transfer(SCNT)are needed for gene editing in cattle.In this point of view,electroporation in embryos has been risen as an alternative.Results First,editing efficiency of our electroporation methods were tested for embryos.Presence of mutation on embryo was confirmed by T7E1 assay.With first combination,mutation rates for MSTN and PRNP were 57.6%±13.7%and 54.6%±13.5%,respectively.In case of MSTN/BLG,mutation rates were 83.9%±23.6%for MSTN,84.5%±18.0%for BLG.Afterwards,the double-KO embryos were transferred to surrogates and mutation rate was identified in resultant calves by targeted deep sequencing.Thirteen recipients were transferred for MSTN/PRNP,4 calves were delivered,and one calf underwent an induction for double KO.Ten surrogates were given double-KO embryos for MSTN/BLG,and four of the six calves that were born had mutations in both genes.Conclusions These data demonstrated that production of genome edited cattle via electroporation of RNP could be effectively applied.Finally,MSTN and PRNP from beef cattle and MSTN and BLG from dairy cattle have been born and they will be valuable resources for future precision breeding. | Gyeong-Min Gim Kyeong-Hyeon Eom Dong-Hyeok Kwon Dae-Jin Jung Dae-Hyun Kim Jun-Koo Yi Jae-Jung Ha Ji-Hyun Lee Seong-Beom Lee Woo-Jae Son Soo-Young Yum Won-Wu Lee Goo Jang | 2024 | Journal of Animal Science and Biotechnology2024，15，1： | 0 |
| 8 | All-Optical WDM Buffer System Realized by NOLM and Feedback Loop Structure显示文摘We propose an all-optical WDM buffer for optical packet switching system, which consists of NOLM and feedback loop. The proposed structure provides more than 40 turn buffering and nice output of buffered data when selected by control signal. | Seungwoo Yi Kyeong-Mo Yoon Yong-Gi Lee Jinseob Eom | 2003 | 光学学报2003，23，S1： | 0 |
| 9 | Real-world outcomes of ibrutinib therapy in Korean patients with relapsed or refractory mantle cell lymphoma:amulticenter,retrospective analysis显示文摘Dear Editor,Despite the introduction of novel front-line therapies including rituximab plus high-dose cytarabine followed by consolidative autologous stem cell transplantation(ASCT)and salvage therapy with bendamustine,lenalidomide or bortezomib,mantle cell lymphoma(MCL)is still considered incurable and most patients experience relapse or refractory(RR)disease. | Jun Ho Yi Seok Jin Kim Dok Hyun Yoon Cheolwon Suh Myung Hee Chang Deok Hwan Yang Jae-Cheol Jo Shin Young Hyun Hyeon-Seok Eom Jeong-Ok Lee Ji Hyun Kwon Sang Hoon Han Seung-Shin Lee Jae-Yong Kwak Se Hyung Kim Dae Sik Kim Ji Hyun Lee Sung Yong Oh Hun Mo Ryoo Hyo Jung Kim Won Seog Kim | 2021 | Cancer Communications2021，41，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员