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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Identification of a novel cardenolide ' ' Calotropis (2-oxovoruscharm) from procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses 显示文摘 | Eric VQ Gentiane S Auretlie A | 2005 | J Med Chem2005，48，： | 1 |
| 3 | The Capture and Destruction of Escherichia coli from Simulated Urban Runoff Using Conventional Bioretention Media and Iron Oxide-coated Sand显示文摘 | Zhang Lan Seagren Eric A Davis Allen P Karns Jeffrey S | 2010 | Water Environment Research2010，，8： | 1 |
| 4 | Inter-organizational knowledge transfer:Current themes and future prospects 显示文摘 | Mark E S Marjorie A L Eric W K T | 2008 | Journal of Management Studies2008，45，4： | 1 |
| 5 | Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody显示文摘 | Kenneth A Foon Xiao-Dong Yang Louis M Weiner Arie S Belldegrun Robert A Figlin Jeffrey Crawford Eric K Rowinsky Janice P Dutcher Nicholas J Vogelzang Jared Gollub John A Thompson Garry Schwartz Ronald M Bukowski Lorin K Roskos Gisela M Schwab | 2004 | International Journal of Radiation Oncology Biology Physics2004，，3： | 1 |
| 6 | Mutagenesis analysis of the nsp4 main proteinase reveals determinants of arterivirus replicase polyprotein autopro- cessing 显示文摘 | DANNY V A ERIC J S ALEXANDER E G | 2006 | J Virol2006，80，7： | 1 |
| 7 | Synthesis of a novel fluorescent poly(D,L-lactide) end-capped with 1-pyrenebutanol used for the preparation of nanoparticles显示文摘 | Cung A N Eric A Gregoire S | 2003 | European Journal of Pharmaceutical Sciences2003，20，2： | 1 |
| 8 | Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer:2010 update by the infectious diseases society of america显示文摘 | Alison G F Eric J B Kent A S | | 0，，04： | 1 |
| 9 | MicroRNA: implications for cancer 显示文摘 | Stefanie S Eric A Carlos C | 2008 | Virchows Arch2008，452，1： | 1 |
| 10 | Synthesis and ceramic conversion ceactions of pinacol- borane-and diethylborazine-modified poly ( vinylsilox- ane) s The development of a processable single-source polymeric precursor to Boron-modified silicon carbide 显示文摘 | BRUNNER A R BUJALSKI D R ERIC S | 2000 | Chem Mater2000，，12： | 1 |
| 11 | Application of Multi-Component Biopolymer Layers to Improve the Freezethaw Stability of Oil-in-water Emulsions: β-Lactoglobulin-t-carrageenan- Gelatin 显示文摘 | YEUN S G ERIC A D JULIAN MCCLEMENTS D | 2007 | Journal of Food Engineering2007，80，： | 1 |
| 12 | Electropolymerization of ferrocene bis-amide derivatives: a possible route to an electrochemical sensory device显示文摘 | Moutet J C Eric S A Ungureanu M | 1996 | Electroanal Chem1996，410，1： | 1 |
| 13 | Long- range oxidation of guanine by Ru (111) in duplex DNA 显示文摘 | Michelle R A Eric D A S Sabine C P | 1997 | Chem Biol1997，4，： | 1 |
| 14 | IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis显示文摘 | Malamut Georgia El Machhour Raja Montcuquet Nicolas Martin-Lannerée Séverine Dusanter-Fourt Isabelle Verkarre Virginie Mention Jean-Jacques Rahmi Gabriel Kiyono Hiroshi Butz Eric A Brousse Nicole Cellier Christophe Cerf-Bensussan Nadine Meres | 2010 | Journal of Clinical Investigation2010，，6： | 1 |
| 15 | Long-term recovery of PCB-contaminated surface sediments at the Sangamo-westonl Twelvemile Creek/lake Hartwell Superfund Site 显示文摘 | Brenner Richard C Magar Victor S Ickes Jennifer A Foote Eric A Abbott James E Bingler Linda S Crecelius Eric A | 2004 | Environmental Science & Technology2004，38，8： | 1 |
| 16 | Surgery for non-specificity neck pain显示文摘 | Eric S Wieser A Jeffrey C | 2007 | Neurosurgery2007，60，1： | 1 |
| 17 | Impact of citric acid on the tenderness,microstructure and oxidative stability of beef muscle显示文摘 | KE S M HUANG Y ERIC A | | 0，，： | 1 |
| 18 | Estrogen as a Neuroprotective Agent in the Treatment of Spinal Cord Injury 显示文摘 | Eric A S James M W Denorah D M | 2003 | New York Academy of Sciences2003，993，： | 1 |
| 19 | The role of visualization incomputer science education显示文摘 | Eric F Monika A Clifford A S | 2012 | Computers in the Schools2012，01，29： | 1 |
| 20 | TPR study on the preparation of impregnated Co/SiO2 catalysts显示文摘 | ERIC V S SEWELL G S MAKHOTHE R A MAKHOTHE CRAIG M HEIKO M MARTIJIN D L CYRIL T O | 1996 | J Catal1996，162，2： | 1 |
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