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1篇 您的检索式：作者名="Erjian Lin"

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		题名	作者	年代	出处	被引量
	1	Does diffusion tensor data reflect pathological changes in the spinal cord with chronic injury?显示文摘Magnetic resonance diffusion tensor imaging has been shown to quantitatively measure the early pathological changes in chronic cervical spondylotic myelopathy.In this study,a novel spongy polyurethane material was implanted in the rat C3–5epidural space to establish a rat model of chronic cervical spondylotic myelopathy.Diffusion tensor data were used to predict pathological changes.Results revealed that the fractional anisotropy value gradually decreased at 4,24,and 72 hours and1 week after injury in rat spinal cord,showing a time-dependent manner.Average diffusion coefficient increased at 72 hours and 1 week after implantation.Hematoxylin-eosin staining and Luxol-fast-blue staining exhibited that the number of neurons in the anterior horn of the spinal cord gray matter and the nerve fiber density of the white matter gradually reduced with prolonged compression time.Neuronal loss was most significant at 1 week after injury.Results verified that the fractional anisotropy value and average diffusion coefficient reflected the degree of pathological change in the site of compression in rat models at various time points after chronic spinal cord compression injury,which potentially has a reference value in the early diagnosis of chronic cervical spondylotic myelopathy.	Erjian Lin Houqing Long Guangsheng Li Wanlong Lei	2013	Neural Regeneration Research2013，8，36：	2

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