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| 1 | Fecal microflora in healthy infants born by different methods of delivery:permanent changes in intestinal flora after caesarean delivery显示文摘 | Gronlund MM Lehtonen OP Erola E | | 0，，01： | 1 |
| 2 | The Finnish evidence-based guideline for open-angle glaucoma 显示文摘 | Tuulonen A Airaksinen PJ Erola E | 2003 | Acta Ophthalmol Scand2003，81，： | 1 |
| 3 | Efficacy of bilatoral subthalamie nucleus (STN) stimulation in Parkiusou's disease显示文摘 | Erola T Heikkinen ER Haapaniemi T | 2006 | Acts Neurochir2006，148，4： | 1 |
| 4 | A new fuzzy multi criteria framework for measuring sustainability performance of a supply chain显示文摘 | Ismail Erola Safiye Sencer Ramazan Sari | | 0，，70： | 1 |
| 5 | Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyll- methionine as cofactor显示文摘 | Jansson A Koskiniemi H Erola A | 2005 | Biol Chem2005，280，： | 1 |
| 6 | The Finnish evidence-based guideline for open-angle glaucoma显示文摘 | Tuulonen A Airaksinen P J Erola E | 2003 | Acta Ophthalmol Scand2003，81，1： | 1 |
| 7 | Characterization of a glass-ceramicproduced from thermal power plant fly ashes 显示文摘 | Erola M Gencb A Ovecoglu M L | 2000 | European Ceramic So-ciety2000，20，： | 1 |
| 8 | Family functioning of patients with an eating disorder compared with that of patients with obsessive compulsive disorder显示文摘 | Erola A Yazici F Toprak G | 2007 | Comprehensive Psychiatry2007，48，： | 1 |
| 9 | A multi-agent based approach to dynamic scheduling of machines and automated guided vehi- cles in manufacturing systems 显示文摘 | Rizvan Erola Cenk Sahina Adil Baykasoglub | 2012 | Applied Soft Computing2012，12，： | 1 |
| 10 | Survey of ground water pesticide pollution in rural areas of Catalonia (Spain)显示文摘 | Garrido T Fraile J Ni(n)erola JM Figuer as M Ginebreda A Olivella L | | 0，，01： | 1 |
| 11 | Occipital morphology an anatomic guide to internal fixation显示文摘 | Zippickr M Erola AA Group J | 1996 | Spine1996，21，： | 1 |
| 12 | X-ray reflectivity of bent perfect crystals in Bragg and Laue Geometry显示文摘 | Erola E Etelaniemi V Suortti P | 1990 | Journal of Applied Crystallography1990，23，1： | 1 |
| 13 | Anatomical studies of hypospadias显示文摘 | Baskin L ErolA Li Y | | 0，，3： | 1 |
| 14 | Efficacy of bilateral subthalamic nucleus (STN) stimulation in Parkinson's disease显示文摘 | EROLA T HEIKKINEN E R HAAPANIEMI T | 2006 | Acta Neurochirurgica2006，148，4： | 1 |
| 15 | Neuromuscular adaptations during concurrent strength and endurance training versus strength training显示文摘 | K. H?kkinen M. Alen W. J. Kraemer E. Gorostiaga M. Izquierdo H. Rusko J. Mikkola A. H?kkinen H. Valkeinen E. Kaarakainen S. Romu V. Erola J. Ahtiainen L. Paavolainen | 2003 | European Journal of Applied Physiology2003，，1： | 1 |
| 16 | Formation of biogenic amine during ripening of dry sausages as effected by starter culture and thawing time of raw materials显示文摘 | Maijala R Erola S Hill P | 1995 | Food Sci1995，60，6： | 1 |
| 17 | Anatomical studies of hypos- padias显示文摘 | Baskin L ErolA Li Y | 1998 | Urol1998，160，32： | 1 |
| 18 | Genetic mechanisms of critical illness in Covid-19显示文摘Host-mediated lung inflammation is present,1 and drives mortality,2 in critical illness caused by Covid-19.Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development.3 Here we report the results of the GenOMICC(Genetics Of Mortality In Critical Care)genome-wide association study(GWAS)in 2244 critically ill Covid-19 patients from 208 UK intensive care units(ICUs).We identify and replicate novel genome-wide significant associations,on chr12q24.13(rs10735079,p=1.65[Formula:see text]10-8)in a gene cluster encoding antiviral restriction enzyme activators(OAS1,OAS2,OAS3),on chr19p13.2(rs2109069,p=2.3[Formula:see text]10-12)near the gene encoding tyrosine kinase 2(TYK2),on chr19p13.3(rs2109069,p=3.98[Formula:see text]10-12)within the gene encoding dipeptidyl peptidase 9(DPP9),and on chr21q22.1(rs2236757,p=4.99[Formula:see text]10-8)in the interferon receptor gene IFNAR2.We identify potential targets for repurposing of licensed medications:using Mendelian randomisation we found evidence in support of a causal link from low expression of IFNAR2,and high expression of TYK2,to life-threatening disease;transcriptome-wide association in lung tissue revealed that high expression of the monocyte/macrophage chemotactic receptor CCR2 is associated with severe Covid-19.Our results identify robust genetic signals relating to key host antiviral defence mechanisms,and mediators of inflammatory organ damage in Covid-19.Both mechanisms may be amenable to targeted treatment with existing drugs.Large-scale randomised clinical trials will be essential before any change to clinical practice. | Erola Pairo-Castineira | 2020 | 四川生理科学杂志2020，42，4： | 0 |
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