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| 1 | Diagnostic accuracy of endoscopic ultrasound in pancreatic neuroendocrine tumors: A systematic review and meta analysis显示文摘AIM: To detect pancreatic neuroendocrine tumors (PNETs) has been varied. This study is undertaken to evaluate the accuracy of endoscopic ultrasound (EUS) in detecting PNETs.METHODS: Only EUS studies confirmed by surgery or appropriate follow-up were selected. Articles were searched in Medline, Ovid journals, Medline nonindexed citations, and Cochrane Central Register of Controlled Trials and Database of Systematic Reviews. Pooling was conducted by both fixed and random effects model). RESULTS: Initial search identified 2610 reference articles, of these 140 relevant articles were selected and reviewed. Data was extracted from 13 studies (n = 456) which met the inclusion criteria. Pooled sensitivity of EUS in detecting a PNETs was 87.2% (95%CI: 82.2-91.2). EUS had a pooled specificity of 98.0% (95%CI: 94.3-99.6). The positive likelihood ratio of EUS was 11.1 (95%CI: 5.34-22.8) and negative likelihood ratio was 0.17 (95%CI: 0.13-0.24). The diagnostic odds ratio, the odds of having anatomic PNETs in positive as compared to negative EUS studies was 94.7 (95%CI: 37.9-236.1). Begg-Mazumdar bias indicator for publication bias gave a Kendall's tau value of 0.31 (P = 0.16), indication no publication bias. The P for χ2 heterogeneity for all the pooled accuracy estimates was > 0.10. CONCLUSION: EUS has excellent sensitivity and specificity to detect PNETs. EUS should be strongly considered for evaluation of PNETs. | Srinivas R Puli Nikhil Kalva Matthew L Bechtold Smitha R Pamulaparthy Micheal D Cashman Norman C Estes Richard H Pearl Fritz-Henry Volmar Sonu Dillon Michael F Shekleton David Forcione | 2013 | World Journal of Gastroenterology2013，19，23： | 14 |
| 2 | Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders显示文摘Inappropriate T cell responses in the central nervous system(CNS)affect the pathogenesis of a broad range of neuroinflammatory and neurodegenerative disorders that include,but are not limited to,multiple sclerosis,amyotrophic lateral sclerosis,Alzheimer’s disease and Parkinson’s disease.On the one hand immune responses can exacerbate neurotoxic responses;while on the other hand,they can lead to neuroprotective outcomes.The temporal and spatial mechanisms by which these immune responses occur and are regulated in the setting of active disease have gained significant recent attention.Spatially,immune responses that affect neurodegeneration may occur within or outside the CNS.Migration of antigen-specific CD4+T cells from the periphery to the CNS and consequent immune cell interactions with resident glial cells affect neuroinflammation and neuronal survival.The destructive or protective mechanisms of these interactions are linked to the relative numerical and functional dominance of effector or regulatory T cells.Temporally,immune responses at disease onset or during progression may exhibit a differential balance of immune responses in the periphery and within the CNS.Immune responses with predominate T cell subtypes may differentially manifest migratory,regulatory and effector functions when triggered by endogenous misfolded and aggregated proteins and cell-specific stimuli.The final result is altered glial and neuronal behaviors that influence the disease course.Thus,discovery of neurodestructive and neuroprotective immune mechanisms will permit potential new therapeutic pathways that affect neuronal survival and slow disease progression. | Kristi M Anderson Katherine E Olson Katherine A Estes Ken Flanagan Howard E Gendelman R Lee Mosley | 2014 | Translational Neurodegeneration2014，3，1： | 8 |
| 3 | The Holonic Enterprise and Theory Emergence: On Emergent Features of Self-Organization in Distributed Virtual Agents显示文摘 | Mihaela U Este R A | 2004 | International Journal Cybernetics and Human Knowing2004，11，1： | 1 |
| 4 | Radioimmunotherapywithiodine(131) I tositumomab for relapsed or refractory B-cell non-Hodgkin's lymphoma:updated results and long-term follow-up of the University ofMichigon experience显示文摘 | Kaminski M S Estes J Zasadny K R | 2000 | Blood2000，96，4： | 1 |
| 5 | Powering the Fiber Loop Optically-a Cost Analysis显示文摘 | BANWELL T C ESTES R C REITH L A | 1993 | Journal of Light Wave Technology1993，11，3： | 1 |
| 6 | Localization and quantification of carbonic anhydrase activity in the symbiotic scyphozoan Cassiopea acamachana 显示文摘 | Estes A M Kempf S C Henry R P | 2003 | Bio- logical Bulletin2003，204，3： | 1 |
| 7 | Early social attention impairments in autism:social orienting,joint attention,and attention to distress显示文摘 | Dawson G Toth K Abbott R Osterling J Munson J Estes A Liaw J | 2004 | Dev Psychol2004，40，2： | 1 |
| 8 | Damaged intestinal epithelial integrity linked to microbial transloeation in pathogenic simian immunodeficiency virus infections显示文摘 | Estes J D Harris L D Klatt N R | 2010 | PLoS pathogens2010，6，10： | 1 |
| 9 | Diagnosis of noneultivatable gastroentefitis viruses, the human caliciviruses显示文摘 | Atmar R L Estes M K | 2001 | Clin Microbiol Rev2001，14，1： | 1 |
| 10 | Improving executive decisions by formalizing dissent: the corporate devil's advocate 显示文摘 | HERBERT T T ESTES R W | 1977 | Academy of Management Review1977，2，4： | 1 |
| 11 | Cognitive task analysis显示文摘 | Clark R E Estes F | 1996 | International Journal of Educational Research1996，25，： | 1 |
| 12 | Introduction of an emerging technology device through PowerPoint training显示文摘 | Estes R Ishee J | 2007 | The Intemet Journal of Allied Health Sciences and Practice2007，5，2： | 1 |
| 13 | Fibroproliferative phase of ARDS:clinical findings and effects of corticosteroids显示文摘 | Meduri G U Belenchia J M Estes R J | 1991 | Chest1991，100，： | 1 |
| 14 | Nectar fluorescence under ultraviolet irradiation显示文摘 | THROP R W BRIGGS D L ESTES J R ERICKSON E H | 1975 | Science1975，189，： | 1 |
| 15 | Competitive optimiza-tion of compressed sensing显示文摘 | M Andrecut R A Este S A Kauffman | 2007 | Journal of Physics A:Mathe-matical and Theoretical2007，40，16： | 1 |
| 16 | Performance-enhancing substances in sports:a review of the literature显示文摘 | Momaya A Fawal M Estes R | 2015 | Sports Med2015，45，4： | 1 |
| 17 | Oxidation of lipids and proteins in frankfurters with different fatty acid compositions and tocopherol and phenolic contents显示文摘 | Estévez M Ventanas S Cava R | 2007 | Food Chemistry2007，100，1： | 1 |
| 18 | Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group(RCWG)显示文摘 | Matthijnssens J Ciarlet M McDonald S M Attoui H Banyai K Brister J R Buesa J Esona M D Estes M K Gentsch J R Iturriza-Gomara M Johne R Kirkwood C D Martella V Mertens P P Nakagomi O Parre ? o V Rahman M Ruggeri F M Saif L J Santos N Steyer A Taniguchi K Patton J T Desselherger U Van Ranst M | 2011 | Arch Virol2011，156，8： | 1 |
| 19 | The pathogenesis of Ventilatorassociated pneumonia:Imechanismas of bacterial transcolonization and airway intensive显示文摘 | Estes R J Meduri G U | 1995 | Intensive Care Med1995，21，： | 1 |
| 20 | Fibroproliferative phase of ARDS显示文摘 | BELENCHIA J M ESTES R J | 1991 | Chest1991，100，： | 1 |
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