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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Stability of a four-vortex aircraft wake mod- el 显示文摘 | Fabre D Jacquin L | 2000 | Physics of Fluids2000，12，10： | 1 |
| 3 | Instability and unsteadiness of aircraft wake vortices显示文摘 | Jacquin L Fabre D Sipp D | 2003 | Aerospace Science and Technolo- gy2003，7，8： | 1 |
| 4 | A novel mutation in the bone morphogenetic protein 15 gene causing defective pro-tein secretion is associated with both increased ovulation rate and sterility in lacaune sheep显示文摘 | Bodin L Pasquale E D Fabre S | 2007 | Endocrinology2007，148，1： | 1 |
| 5 | Optimal perturbations in a four-vortex aircraft wake in counter-rotating configuration 显示文摘 | Fabre D Jacquin L Loof A | 2002 | Journal of Fluid Mechanics2002，451，： | 1 |
| 6 | Instability and un- steadiness of aircraft wake vortiees显示文摘 | Jacquin L Fabre D Sipp D | 2003 | Aerospace Science and Technology2003，7，8： | 1 |
| 7 | Transfer factors as immunotherapy and supplement of chemotherapy in experimental pulmonary tuberculosis显示文摘 | Fabre R A Perez T M Aguilar L D | 2004 | Clin Exp Immunol2004，136，2： | 1 |
| 8 | Stability of a four-vortex aircraft wake model显示文摘 | Fabre D Jacquin L | 2000 | Physics of Fluids2000，12，10： | 1 |
| 9 | Prenatal and postnatal ciliated hepatic foregut cysts in infants显示文摘 | Florent Guérin Rim Hadhri Monique Fabre Danièle Pariente Virginie Fouquet Hélène Martelli Frédéric Gauthier Sophie Branchereau | 2010 | Journal of Pediatric Surgery2010，，3： | 1 |
| 10 | Optimal perturbations in a four-vortex aircraft wake in counter rotating configuration显示文摘 | Fabre D Jacquin L Loof A | 2002 | Journal of tquid Mechanics2002，451，1： | 1 |
| 11 | Structure of a steady drain-hole vortex in a viscous fluid显示文摘 | Bhling L Andersen A Fabre D | 2010 | Journal of Fluid Mechanics2010，656，： | 1 |
| 12 | Optimal perturbations in a four-vortex aircraft wake in counter-rotating configuration显示文摘 | Fabre D Jacquin L Loof A | 2002 | Journal Fluid Mechanics2002，451，： | 1 |
| 13 | Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis 显示文摘 | Supply P Marceau M Mangenot S Roche D Rouanet C Khanna V Majlessi L Criscuolo A Tap J Pawlik A Fiette L Orgeur M Fabre M Parmentier C Frigui W Simeone R Boritsch EC Debrie AS Willery E Walker D Quail MA Ma L Bouchier C Salvignol G Sayes F Cascioferro A Seemann T Barbe V Locht C Gutierrez MC Leclerc C Bentley SD Stinear TP Brisse S Madigue C Parkhill J Cruveiller S Brosch R | 2013 | Nat Genet2013，45，2： | 1 |
| 14 | Transfer factors as immunotherapy and supplement of chemotherapy in experimental pulmonary tuberculosis显示文摘 | Fabre R A Perez T M Aguilar L D | 2004 | Clin Exp Immunol2004，，136： | 1 |
| 15 | Microstructure, rhoology and storage stability of low-fat yoghurt structured by carrot cell wall particles显示文摘 | MCCANN T H FABRE D L | 2011 | Food Research International2011，44，： | 1 |
| 16 | A novel mutation in the bone morphogenetic protein15gene causing defective protein se-cretion is associated with both increased ovulation rate and sterility in lacaune sheep显示文摘 | BODIN L PASQUALE E D FABRE S | 2007 | Endocrinology2007，148，1： | 1 |
| 17 | Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewes显示文摘 | Mulsant P Lecerf F Fabre S Schibler L Monget P Lanneluc I Pisselet C Riquet J Monniaux D Callebaut I Cribiu E Thimonier J Teyssier J Bodin L Cognié Y Chitour N Elsen JM | | 0，，： | 1 |
| 18 | A nano-hydroxyapatite – Pullulan/dextran polysaccharide composite macroporous material for bone tissue engineering显示文摘 | Jean Christophe Fricain Silke Schlaubitz Catherine Le Visage Isabelle Arnault Sidi Mohammed Derkaoui Robin Siadous Sylvain Catros Charlotte Lalande Reine Bareille Martine Renard Thierry Fabre Sandro Cornet Marlène Durand Alain Léonard Nouredine Sahraoui D | 2013 | Biomaterials2013，，12： | 1 |
| 19 | Stability of a four-vortex aircraft wake model显示文摘 | Fabre D Jacquin L | 2000 | Physics of Fluids2000，12，10： | 1 |
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