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| 1 | A role for the RNA-binding protein MOS2 in microRNA maturation in Arabidopsis显示文摘microRNAs (miRNAs ) 玩在基因表示的规定的重要角色。在 Arabidopsis,成熟 miRNAs 被形成用色子赌博的身体(D 身体) 的原子 HYL1/SE/DCL1 建筑群从主要 miRNA 抄本(pri-miRNAs ) 处理。这里,我们报导 RNA 有约束力的蛋白质 MOS2 绑在 pri-miRNAs 并且涉及 pri-miRNAs 的有效处理。MOS2 不与 HYL1, SE,和 DCL1 交往并且不在 D 身体是局部性的。当 MOS2 不在时,有趣地,由 HYL1 的 pri-miRNAs 的招募极大地被减少,在 D 身体的 HYL1 的本地化被损害。这些数据建议 MOS2 支持通过由用色子赌博的建筑群便于 pri-miRNAs 的招募处理的 pri-miRNA。 | Xueying Wu Yupeng Shi Jingrui Li Le Xu Yuda Fang Xin Li Yijun Qi | 2013 | Cell Research2013,23,5: | 7 |
| 2 | Lamin-like Proteins Negatively Regulate Plant Immunity through NAC WITH TRANSMEMBRANE MOTIF1-LIKE9 and NONEXPRESSOR OF PR 3ENES1 in Arabidopsis thaliana显示文摘 | Tongtong Guo Xuegao Mao Hui Zhang Yu Zhang Mengdi Fu Zhenfei Sun Peng Kuai Yonggen Lou Yuda Fang | 2017 | Molecular Plant2017,10,10: | 3 |
| 3 | Histone 3 lysine 36 to methionine mutations stably interact with and sequester SDG8 in Arabidopsis thaliana显示文摘Post-transcriptional modifications of histones play important roles in various biological processes. Here, we report that Arabidopsis plants overexpressing histone H3 lysine to methionine mutations at histone H3.1K36(H3.1K36M) and H3.3K36(H3.3K36M) have serious developmental defects with early-flowering and change in the modifications of endogenous histone H3, including acetylation at lysine 9(H3K9ac), trimethylation at lysine 27(H3K27me3), di-and tri-methylation at lysine 36(H3K36me2 and H3K36me3). In addition, H3K36M mutation alters its subcellular localization and interacts with H3K36 methyltransferase SDG8. Our results support a model in which H3K36M stably interacts with SDG8, and inhibits the activity of SDG8 by sequestering SDG8, resulting in a dominant negative effect to affect the proper expression levels of a variety of genes and plant development. | Guang Lin Ying Zhou Min Li Yuda Fang | 2018 | Science China(Life Sciences)2018,61,2: | 3 |
| 4 | Histone variants: the artists of eukaryotic chromatin显示文摘The eukaryotic genome is packaged into a complex nucleoprotein structure named chromatin, balancing the compactness of genome and the accessibility of regulatory proteins and RNA polymerases to DNA. The mechanisms of the regulation of chromatin dynamics include the post-translational modification of histones, alteration of nucleosome positions by chromatin remodelers, replacement of canonical histones by histone variants with the aid of histone chaperones, and dynamic organization of the three-dimensional genome in the small nucleus. Histone variants are different from canonical histones by substitution of several amino acid residues or changes in amino acid sequence. Histone variants perform specialized functions such as altering nucleosome stability, dynamics, structure, as well as playing critical roles in a range of biological processes like transcriptional regulation, DNA repair and recombination, development and immune responses. Here we discuss how histone variants, their modification and specific loading to chromatin are involved in transcriptional regulation, DNA repair and plant development. | LI Min FANG YuDa | 2015 | Science China(Life Sciences)2015,58,3: | 3 |
| 5 | Echocardiographic detection of early diabetic myocardial disease显示文摘 | Fang ZY Yuda S Anderson V | 2003 | J Am Coll Cardiol2003,41,4: | 1 |
| 6 | Echocardiographic detection of early diabetic myocardial dise&se显示文摘 | Fang ZY Yuda S Anderson V | 2003 | J Am Coll Cardiol2003,41,4: | 1 |
| 7 | Eehocardiographic de- tection of early diabetic myocardial disease 显示文摘 | Fang ZJ Yuda S Anderson V | 2003 | J Am Coil Cardiol2003,41,: | 1 |
| 8 | Echocardiographic detection of early diabetic myocardial disease显示文摘 | Fang ZY Yuda S Anderson V | 2003 | J Am Coll Cardiol2003,41,: | 1 |
| 9 | Association of severe coronary stenosis with subclinical left ventrieular dysfunction in the absence of infarction显示文摘 | Yuda S Fang ZY Marwick TH | 2003 | J Am Soc Echocardiogr2003,16,11: | 1 |
| 10 | Echocardiographic detection of early diabetic myocardial disease 显示文摘 | Yuda S Anderson V | 2003 | J Am Coll Cardiol2003,41,4: | 1 |
| 11 | Echocardiographic detection of early diabetic myocardial disease显示文摘 | FANG Z Y YUDA S ANDERSON V | 2003 | J Am Coll Cardiol2003,41,4: | 1 |
| 12 | Echocardiographic detection of early diabetic myocardial disease显示文摘 | Fang ZY Yuda S Anderson V | 2003 | J Am Coil Cardiol2003,41,4: | 1 |
| 13 | Echocardiographic detection of early diabetic myocardial disease显示文摘 | Fang ZY Yuda S Anderson V | 2003 | J Am Coll Cardiol2003,41,: | 1 |
| 14 | Association of severe coronary stenosis with subclinical left ventricular dysfunction in the absence of infarction显示文摘 | Yuda S Fang ZY Marwick TH | 2003 | J Am Soc Echocardiogr2003,16,11: | 1 |
| 15 | Association of severe coronary stenosis with subcIfnfca] left ventricular dysfunction in the absence of infarction显示文摘 | Yuda S Fang ZY Marwick TH | 2003 | J Am Soc Echocardfogr2003,16,11: | 1 |
| 16 | Association of severe coronary stenosis with subclinical left ventricular dysfunction in the ab sence of infarction显示文摘 | Yuda S Fang ZY Marwick TH | 2003 | J Am Soc Echocardiogr2003,16,11: | 1 |
| 17 | Echocardiographic detection of early diabetic myocardial disease显示文摘 | Fang ZY Yuda S Anderson V | 2003 | J Am Coll Cardiol2003,41,4: | 1 |
| 18 | Echocardiographic detection of early diabetic myocardial disease显示文摘 | Fang ZJ Yuda S Anderson V | 2003 | J Am Coll Cardiol2003,41,: | 1 |
| 19 | Eeh- ocardiographic detection of early diabetic myo- cardial disease 显示文摘 | Fang ZY Yuda S Anderson V | 2003 | J Am Coil Cardiol2003,41,4: | 1 |
| 20 | Echocardiographic detection of early diabetic myocardial disease显示文摘 | Fang ZY Yuda S Anderson V | 2003 | J Am Coil Cardiol2003,41,4: | 1 |