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| 1 | Current medical therapy of inflammatory bowel disease显示文摘INTRODUCTIONThe 1990’s have brought a significant promise and the hopefor a better and brighter future in the new millennium forpatients with inflammatory bowel disease(IBD).A betterunderstanding of the pathophysiology of IBD symptoms hasled to newer treatment modalities and streamlining oftherapy for specific subsets of patients. | Kiron M. Das Sherif A. Farag | 2000 | World Journal of Gastroenterology2000，6，4： | 16 |
| 2 | 骨盆底功能障碍的静态和动态MR成像表现显示文摘目的前瞻性地分析同期静态和动态MR影像,确定压力性尿失禁(SUI)、盆腔脏器脱出(POP)和肛门失禁是否与特定的盆底异常相关。方法本研究经伦理委员会批准,并获得所有受试者知情同意。共计59例女性,其中15例未生育女性(平均年龄25.6岁)为对照组,病人44例(平均年龄43.4岁)。病人组依据主要症状分为4组。结构紊乱分析采用静态T2加权扰相自旋回波影像,功能异常的诊断则采用功能动态(电影)平衡快速场回波影像。记录5个盆底支持结构的测量结果。两种MRI影像联合分析以确定主要异常。 | R.F. El Sayed S. El Mashed A. Farag M.M. Morsy M.S. A bdel Azim. 赵艳萍(译) 刘文亚(校) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 12 |
| 3 | Real time endoscopic ultrasound elastography and strain ratio in the diagnosis of solid pancreatic lesions显示文摘AIM To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions(SPL). METHODS A total of 172 patients with SPL identified by endoscopic ultrasound were enrolled in the study to evaluate the efficacy of elastography and strain ratio in differentiating malignant from benign lesions. The semi quantitative score of elastography was represented by the strain ratio method. Two areas were selected, area(A) representing the region of interest and area(B) representing the normal area. Area(B) was then divided by area(A). Sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV), and accuracy were calculated by comparing diagnoses made by elastography, strain ratio and final diagnoses.RESULTS SPL were shown to be benign in 49 patients and malignant in 123 patients. Elastography alone had a sensitivity of 99%, a specificity of 63%, and an accuracy of 88%, a PPV of 87% and an NPV of 96%. The best cut-off level of strain ratio to obtain the maximal area under the curve was 7.8 with a sensitivity of 92%, specificity of 77%, PPV of 91%, NPV of 80% and an accuracy of 88%. Another estimated cut off strain ratio level of 3.8 had a higher sensitivity of 99% and NPV of 96%, but with less specificity, PPV and accuracy 53%, 84% and 86%, respectively. Adding both elastography to strain ratio resulted in a sensitivity of 98%, specificity of 77%, PPV of 91%, NPV of 95% and accuracy of 92% for the diagnosis of SPL. CONCLUSION Combining elastography to strain ratio increases the accuracy of the differentiation of benign from malignant SPL. | Hussein Okasha Shaimaa Elkholy Ramy El-Sayed Mohamed-Naguib Wifi Mohamed El-Nady Walid El-Nabawi Waleed A El-Dayem Mohamed I Radwan Ali Farag Yahya El-sherif Emad Al-Gemeie Ahmed Salman Mohamed El-Sherbiny Ahmed El-Mazny Reem E Mahdy | 2017 | World Journal of Gastroenterology2017，23，32： | 11 |
| 4 | Perioperative visual loss after spine surgery显示文摘Perioperative visual loss(POVL) is an uncommon, but devastating complication that remains primarily associated with spine and cardiac surgery. The incidence and mechanisms of visual loss after surgery remain difficult to determine. According to the American Society of Anesthesiologists Postoperative Visual Loss Registry, the most common causes of POVL in spine procedures are the two different forms of ischemic optic neuropathy: anterior ischemic optic neuropathy and posterior ischemic optic neuropathy, accounting for 89% of the cases. Retinal ischemia, cortical blindness, and posterior reversible encephalopathy are also observed, but in a small minority of cases. A recent multicenter case control study has identified risk factors associated with ischemic optic neuropathy for patients undergoing prone spinal fusion surgery. These include obesity, male sex, Wilson frame use, longer anesthetic duration, greater estimated blood loss, and decreased percent colloid administration. These risk factors are thought to contribute to the elevation of venous pressure and interstitial edema, resulting in damage to the optic nerve by compression of the vessels that feed the optic nerve, venous infarction or direct mechanical compression. This review will expand on these findings as well as the recently updated American Society of Anesthesiologists practice advisory on POVL. There are no effectivetreatment options for POVL and the diagnosis is often irreversible, so efforts must focus on prevention and risk factor modification. The role of crystalloids versus colloids and the use of α-2 agonists to decrease intraocular pressure during prone spine surgery will also be discussed as a potential preventative strategy. | Travis J Nickels Mariel R Manlapaz Ehab Farag | 2014 | World Journal of Orthopedics2014，5，2： | 7 |
| 5 | Corneal sensitivity,ocular surface health and tear film stability after punctal plug therapy of aqueous deficient dry eye显示文摘·AIM: To evaluate the effect of punctal occlusion using thermosensitive(smart plug) versus silicone plug for management of aqueous deficient dry eye on cornea sensitivity, ocular surface health and tear film stability.·METHODS: A comparative prospective interventiona case study included 45 patients with bilateral severe form of aqueous deficient dry eye. In each patient, the smar plug was inserted in the lower punctum of the right eye which was considered as study group 1 and silicone plug was inserted in the lower punctum of the left eye o the same patient which was considered as study group2. All patients were subjected to careful history taking and questionnaire for subjective assessment of severity of symptoms. Corneal sensitivity, corneal fluorescein rose bengal staining, Schirmer's I test, tear film break up time and conjunctival impression cytology were performed pre and 1, 3 and 6mo post plug insertion.·RESULTS: A statistically significant improvement in subjective and objective manifestations occurred following treatment with both types of plugs(P <0.01)The thermosensitive plug caused significant overal improvement, decrease in frequency of application o tear substitutes and improvement of conjunctiva impression cytology parameters in the inserted side(P <0.01). Canaliculitis was reported in two eyes(4.4% following punctal occlusion using thermosensitive plug(study group 1). Spontaneous plug loss occurred in 21eyes(46.6%) in the silicone plug group(study group 2).·CONCLUSION: Improvement of subjective and objective manifestations of aqueous deficient dry eye occurs following punctal plug occlusion. Thermosensitive plug has good patient's compliance with fewer complications and lower rates of loss compared to the silicone plug. | Azza Mohamed Ahmed Said Mona Elsayed Farag Tarek Mohamed Abdulla Othman Ali Othman Ziko Wesam Mohamed Osman | 2016 | International Journal of Ophthalmology(English edition)2016，9，11： | 4 |
| 6 | 化学信息素及其在害虫防治中的潜在应用显示文摘化学通讯在昆虫的生存中起着重要而关键的作用,使昆虫能够通过调整它们的行为来评估其所处的当前环境。化学信息素是昆虫用来传递特定化学信息的有机化合物,所传递之信息可以改变昆虫行为或生理。化学信息素一词源于希腊语“semeon”,意思是标志或信号。昆虫使用化学信息素来确定异性、寄主或食物的位置,避免竞争,逃避天敌,克服寄主对它们的天然防御系统。与其他昆虫传递信息的方式(如触碰)相比,化学信息素具有克服相对远距离的优势。化学信息素的分子量取决于碳链长短,故各不相同。环境中非常低浓度的信息素也有生物活性,故其化学表征较为复杂。 | Hamadttu Abdel Farag El-Shafie Jose Romeno Faleiro 余武秀 | 2020 | 世界农药2020，42，1： | 4 |
| 7 | 菊酯类药剂对草地贪夜蛾的毒力及对钠离子通道的诱导特性显示文摘为明确菊酯类药剂对草地贪夜蛾Spodoptera frugiperda的防治效果,采用点滴法在室内测定高效氯氟氰菊酯、高效氯氰菊酯、联苯菊酯、溴氰菊酯和茚虫威原药对草地贪夜蛾3龄幼虫的毒力,利用实时荧光定量PCR技术测定3龄幼虫在这5种药剂诱导不同时间下其体内钠离子通道基因片段的表达量变化。结果显示,高效氯氟氰菊酯、溴氰菊酯、联苯菊酯、茚虫威和高效氯氰菊酯这5种药剂处理草地贪夜蛾3龄幼虫24 h后的LD50值分别为74.911、83.280、152.662、179.372、567.250 mg/L;处理48 h后的LD50值分别为18.946、67.874、120.888、132.790、461.635 mg/L;同时发现草地贪夜蛾3龄幼虫钠离子通道基因的表达均呈现不被诱导或诱导下调现象,表明草地贪夜蛾幼虫可通过降低靶标基因的表达量进而减少药剂对其的毒性。表明供试4种拟除虫菊酯类药剂和1种氯虫苯甲酰胺类药剂可作为草地贪夜蛾田间应急防控药剂施用。 | 李芬 王力奎 彭正强 MALHAT Farag 吕宝乾 吴少英 | 2020 | 植物保护学报2020，47，4： | 4 |
| 8 | Shellfish allergy and relation to iodinated contrast media: United Kingdom survey显示文摘AIM: To assess current practice of United Kingdom cardiologists with respect to patients with reported shellfish/iodine allergy, and in particular the use of iodinated contrast for elective coronary angiography.Moreover we have reviewed the current evidence-base and guidelines available in this area.METHODS: A questionnaire survey was send to 500senior United Kingdom cardiologists(almost 50% cardiologists registered with British Cardiovascular Society)using email and first 100 responses used to analyze practise. We involved cardiologists performing coronary angiograms routinely both at secondary and tertiary centres. Three specific questions relating to allergy were asked:(1) History of shellfish/iodine allergy in pre-angiography assessment;(2) Treatments offeredfor shellfish/iodine allergy individuals; and(3) Any specific treatment protocol for shellfish/iodine allergy cases. We aimed to establish routine practice in United Kingdom for patients undergoing elective coronary angiography. We also performed comprehensive PubMed search for the available evidence of relationship between shellfish/iodine allergy and contrast media.RESULTS: A total of 100 responses were received, representing 20% of all United Kingdom cardiologists. Ninety-three replies were received from consultant cardiologists, 4 from non-consultant grades and 3 from cardiology specialist nurses. Amongst the respondents, 66% routinely asked about a previous history of shellfish/iodine allergy. Fifty-six percent would pre-treat these patients with steroids and anti-histamines. The other 44% do nothing, or do nonspecific testing based on their personal experience as following:(1) Skin test with 1 mL of subcutaneous contrast before intravenous contrast;(2) Test dose 2 mL contrast before coronary injection;(3) Close observation for shellfish allergy patients; and(4) Minimal evidence that the steroid and anti-histamine regime is effective but it makes us feel better.CONCLUSION: There is no evidence that allergy to shellfish alters the risk of reaction to intravenous contrast more than any other allergy and asking about such allergies in pre-angiogram assessment will not provide any additional information except propagating the myth. | Mudassar Baig Ahmad Farag Jamal Sajid Rahul Potluri R Bruce Irwin Hafiz Mohammed Idrees Khalid | 2014 | World Journal of Cardiology2014，6，3： | 3 |
| 9 | No association of the cytotoxic T-lymphocyte associated gene CTLA4 +49A/G polymorphisms with Crohn's disease and ulcerative colitis in Hungarian population samples显示文摘瞄准:当前的工作的目标细胞毒素的 T 淋巴细胞抗原是分析 +49A/G 的流行变体的在有 Crohn 的匈牙利病人的 4 基因(CTLA4 )?ˉs 疾病(CD ) 和 ulcerative (UC ) 。方法:有 CD 的 130 个无关的题目的一个总数并且 150 与 UC,和 170 匹配的控制是为单个核苷酸多型性(SNP ) 的 genotyped。遗传型被使用 PCR/RFLP 测试决定。结果:G 等位基因频率和 GG 遗传型的流行在 CD 组,是 38.1% 和 12.3%40.6% 和 18.6% 在 UC 病人,并且 37.4% 和 15.9% 在控制组分别地。结论:当前的学习的结果显示出 +49G SNP 的那辆马车在异质接合或不在匈牙利人口为 CD 或为 UC 在同型结合的形式授与风险任何一个。 | Lili Magyari Bernadett Faragó Judit Bene Katalin Horvatovich Lilla Lakner Márta Varga Mária Figler Beáta Gasztonyi Gyula Mózsik Béla Melegh | 2007 | World Journal of Gastroenterology2007，13，15： | 3 |
| 10 | Gastrointestinal and hepatic diseases during the COVID-19 pandemic:Manifestations,mechanism and management显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is considered the causative pathogen of coronavirus disease 2019(COVID-19)and has become an international danger to human health.Although respiratory transmission and symptoms are still the essential manifestations of COVID-19,the digestive system could be an unconventional or supplementary route for COVID-19 to be transmitted and manifested,most likely due to the presence of angiotensin-converting enzyme 2(ACE2)in the gastrointestinal tract.In addition,SARS-CoV-2 can trigger hepatic injury via direct binding to the ACE2 receptor in cholangiocytes,antibodydependent enhancement of infection,systemic inflammatory response syndrome,inflammatory cytokine storms,ischemia/reperfusion injury,and adverse events of treatment drugs.Gastrointestinal symptoms,including anorexia,nausea,vomiting,and diarrhea,which are unusual in patients with COVID-19,and some digestive signs may occur without other respiratory symptoms.Furthermore,SARS-CoV-2 can be found in infected patients’stool,demonstrating the likelihood of transmission through the fecal-oral route.In addition,liver function should be monitored during COVID-19,particularly in more severe cases.This review summarizes the evidence for extra-pulmonary manifestations,mechanisms,and management of COVID-19,particularly those related to the gastrointestinal tract and liver. | Dina Zakaria Mohamed Mai El-Sayed Ghoneim Sally El-Sayed Abu-Risha Ramy Ahmed Abdelsalam Mohamed Abdelhalem Farag | 2021 | World Journal of Gastroenterology2021，27，28： | 2 |
| 11 | Shopping online and/or in-store? A structural equation model of the relationships between e-shopping and in-store shopping显示文摘 | Sendy Farag Tim Schwanen Martin Dijst Jan Faber | 2006 | Transportation Research Part A2006，，2： | 2 |
| 12 | Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn’s disease patients显示文摘AIM:To investigate the interaction of interleukin-23 receptor(IL23R)(rs1004819 and rs2201841),autophagy-related 16-like 1(ATG16L1)(rs2241880), caspase recruitment domain-containing protein 15 (CARD15)genes,and IBD5 locus in Crohn's disease(CD) patients. METHODS:A total of 315 unrelated subjects with CD and 314 healthy controls were genotyped.Interactions and specific genotype combinations of a total of eight variants were tested.The variants of IBD5locus(IGR2198a_1 rs11739135 and IGR2096a_1 rs12521868),CARD15(R702W rs2066845 and L1007fs rs2066847),ATG16L1(rs2241880)and IL23R (rs1004819,rs2201841)genes were genotyped by PCR-RFLP,the G908R(rs2066844)in CARD15 was determined by direct sequencing. RESULTS:The association of ATG16L1 T300A with CD was confirmed[P=0.004,odds ratio(OR)=1.69, 95%CI:1.19-2.41],and both IL23R variants were found to represent significant risk for the disease(P= 0.008,OR=2.05,95%CI:1.20-3.50 for rs1004819 AA;P<0.001,OR=2.97,95%CI:1.65-5.33 for rs2201841 CC).Logistic regression analysis of pairwise interaction of the inflammatory bowel disease (IBD)loci indicated that IL23R,ATG16L1,CARD15 and IBD5(IGR2198a_1)contribute independently to disease risk.We also analysed the specific combina- tions by pair of individual ATG16L1,IL23R rs1004819, rs2201841,IGR2198a_1,IGR2096a_1 and CARD15 genotypes for disease risk influence.In almost all cases,the combined risk of susceptibility pairs was higher in patients carrying two different risk-associated gene variants together than individuals with just one polymorphism.The highest OR was found for IL23R rs2201841 homozygous genotype with combination of positive CARD15 status(P<0.001,OR=9.15,95% CI:2.05-40.74). CONCLUSION:The present study suggests a cumulative effect of individual IBD susceptibility loci. | Veronika Csngei Luca Járomi EnikSáfrány Csilla Sipeky Lili Magyari Bernadett Faragó Judit Bene Noémi Polgár Lilla Lakner Patrícia Sarlós Márta Varga Béla Melegh | 2010 | World Journal of Gastroenterology2010，16，2： | 2 |
| 13 | Removal of Cd (II) ion from waste water by adsorption onto polyaniline coated on sawdust显示文摘 | M.S. Mansour M.E. Ossman H.A. Farag | 2011 | Desalination2011，，1： | 2 |
| 14 | Synthesis of unsaturated polyester resins based on rosin acrylic acid adduct for coating applications显示文摘 | Ayman M Atta Ashraf M Elsaeed Reem K Farag | 2007 | Reactive and Functional Polymers2007，67，： | 1 |
| 15 | The effect of 03 fumigation during leaf development on photosynthesis of wheat and pea: An invivo analysis 显示文摘 | Farage P K Long S P | 1999 | Photosynthesis Research1999，59，： | 1 |
| 16 | Preparation and characterization of some cationic starches显示文摘 | Farag S Hasham A | 1993 | Starch1993，45，6： | 1 |
| 17 | Natural killer cell receptors:new biology and insights into the graftversus-leukemia effect显示文摘 | Farag SS Fehniger TA Ruggeri L | 2002 | Blood2002，100，6： | 1 |
| 18 | Monoclonal antibodies for the prevention and treatment of graft-versus-host disease显示文摘 | Bruner RJ Farag SS | 2003 | Semin Oncol2003，30，4： | 1 |
| 19 | Towards Trust-Aware Resource Management in Grid Computing Systems显示文摘 | Farag Azzedin Muthucuaaru Maheswaran | 2002 | Proceedings of the 2nd IEEE/ACM International Symposium on Cluster Computing and the Grid2002，，02： | 1 |
| 20 | Evalua- tion of methods used to determine ochratoxin A in coffee beans 显示文摘 | Ahmed N E Farag M M Soliman K M | | Journal of Agricultural and Food Chemistry0，55，23： | 1 |
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