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| 1 | Analysis of characteristics of time-frequency correlations between runoff,tidal range and salinity in the Changjiang Estuary显示文摘Power spectrum and cross-wavelet transform analysis was adopted to study the time-frequency characteristics and multiscale correlations between runoff,tidal range and salinity in the Changjiang Estuary based on the runoff data collected at the Datong Station,the tidal range measured at the Baozhen Station,and the salinity at the Baogang Station from 2008 to 2009.The variations of the salinity showed significant periodicity at scales of 2-3,7-8,14-15 and 26-30 d.The correlation between the salinity and the runoff and the tidal range were found to be significantly related to shock at scales of 5-7,14-15,26-30 d and 0.5 a.The correlation between the runoff and the salinity was mainly in the same phase,while the correlation between the tidal range and the salinity was in the antiphase.Different frequency bands were related to different degrees,and their relevance increased as the resonance frequency decreased.In addition,changes of the seasonal runoff were obvious.Specifically,a point of discontinuity was reached in early June with a cycle of 7-8 d,which coincided with the periodicity of plum rains in the Changjiang-Huaihe region.High-frequency changes (8-16 d period) of the salinity corresponded to the time domain in January-April 2008,February-April 2009 and October-December 2009 and exhibited an approximately 0.5 a (184 d) long frequency oscillation.Short-period changes were found to be stronger than long-period changes.Cross-wavelet transforms for the salinity,the runoff and the tidal range revealed local features in the time domain,while the significant levels of different periodic oscillations were observed in the frequency domain.The correlation characteristics of the salinity and the runoff were significant in the 80-90 d frequency domain,indicating that the major impact of the runoff on the salinity was reflected in seasonal changes.The tidal range on the small scale of 14-15 and 30-32 d was more obvious than the runoff. | FEI Yuejun XU Lili DU Panjun GUAN Qinle KANG Xing XIAO Wenjun | 2011 | Acta Oceanologica Sinica2011，30，5： | 3 |
| 2 | Surface tidal currents in the open sea area to the east of the Zhoushan Islands measured with high frequency surface wave radar显示文摘Based on the quasi-harmonic analysis of 11 d vector ocean currents obtained from two high frequency surface wave radars located at Zhujiajian Island and Shengshan Island,the spatial distribution characteristics of surface tidal currents in the open sea area to the east of the Zhoushan Islands of Zhejiang Province,China are studied.The following conclusions are drawn from the analysis:the tidal current pattern in the open sea area to the east of Zhoushan Islands is primarily regular semidiurnal,which is significantly affected by the shallow water constituents.The directions of the major axes of tidal current ellipses of M2lie approximately in the NW-SE direction.With the increasing of distance away from the coast,the directions of the tidal current ellipses gradually shift toward the E-W direction.The tidal currents are mainly reversing currents.The spatial distribution of probable maximum current velocities decreases gradually from northeast to southwest which is basically in accordance with the spatial distribution of measured maximum current velocities.The residual currents near the coast are larger than those far away from the coast.The directions of the residual currents are basically north by east,and the angle to the due north increases gradually with the increasing distance away from the coast.The topography shows a certain impact on the spatial distribution of shallow water constituents,the rotation of tidal currents,the probable maximum currents and the residual currents. | SHEN Zhiben WU Xiongbin FEI Yuejun XU Xing'an CHEN Xiaofeng | 2013 | Acta Oceanologica Sinica2013，32，10： | 2 |
| 3 | Neurodevelopmental impairment induced by prenatal valproic acid exposure shown with the human cortical organoid-on-a-chip model显示文摘Prenatal exposure to environmental insults can increase the risk of developing neurodevelopmental disorders.Administration of the antiepileptic drug valproic acid(VPA)during pregnancy is tightly associated with a high risk of neurological disorders in offspring.However,the lack of an ideal human model hinders our comprehensive understanding of the impact of VPA exposure on fetal brain development,especially in early gestation.Herein,we present the first report indicating the effects of VPA on brain development at early stages using engineered cortical organoids from human induced pluripotent stem cells(hiPSCs).Cortical organoids were generated on micropillar arrays in a controlled manner,recapitulating the critical features of human brain development during early gestation.With VPA exposure,cortical organoids exhibited neurodevelopmental dysfunction characterized by increased neuron progenitors,inhibited neuronal differentiation and altered forebrain regionalization.Transcriptome analysis showed new markedly altered genes(e.g.,KLHL1,LHX9,and MGARP)and a large number of differential expression genes(DEGs),some of which are related to autism.In particular,comparison of transcriptome data via GSEA and correlation analysis revealed the high similarity between VPA-exposed organoids with the postmortem ASD brain and autism patient-derived organoids,implying the high risk of autism with prenatal VPA exposure,even in early gestation.These new findings facilitate a better understanding of the cellular and molecular mechanisms underlying postnatal brain disorders(such as autism)with prenatal VPA exposure.This established cortical organoid-on-a-chip platform is valuable for probing neurodevelopmental disorders under environmental exposure and can be extended to applications in the study of diseases and drug testing. | Kangli Cui Yaqing Wang Yujuan Zhu Tingting Tao Fangchao Yin Yaqiong Guo Haitao Liu Fei Li Peng Wang Yuejun Chen Jianhua Qin | 2020 | Microsystems & Nanoengineering2020，6，1： | 1 |
| 4 | Ecological thresholds of phytoplankton community across environmental gradients in the harmful algal blooms-frequently-occurring,subtropical coastal waters,East China Sea显示文摘Phytoplankton communities can response immediately and directly to environmental changes,and thus have been applied as reliable biotic indicators in aquatic systems.This study provided insights into the relationships concerning ecological thresholds of phytoplankton communities and individual taxon in response to environmental changes in coastal waters of northern Zhejiang Province,East China Sea.Results demonstrated that there existed seasonal variations of phytoplankton community ecological thresholds of which spring being higher than those in summer.As for individual species,Prorocentrum donghaiense and Noctiluca scintillans were identified as the most tolerant and sensitive indicator species in spring and summer,respectively.They exhibited strong indications in response to environmental changes.These findings highlighted that phytoplankton community structure in this region was stable when environmental gradients were below the thresholds of sensitive species,whereas potential harmful algal blooms may occur when environmental gradients exceeded the thresholds of tolerant species. | Ran Ye Chunying Ge Qiong Wang Qing Xu Guofeng Xu Yongkang Yan Mingli Qin Yanhong Cai Yuejun Fei | 2021 | Acta Oceanologica Sinica2021，40，6： | 0 |
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