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	题名	作者	年代	出处	被引量
1	Coexpression of receptor-tyrosine-kinases in gastric adenocarcinoma-a rationale for a molecular targeting strategy?显示文摘AIM: To define the (co-)expression pattern of target receptor-tyrosine-kinases (RTK) in human gastric adenocarcinoma. METHODS: The (co-)expression pattern of VEGFR1-3,PDGFRα/b and EGFR1 was analyzed by RT-PCR in 51 human gastric adenocarcinomas. In addition,IHC staining was applied for confirmation of expression and analysis of RTK localisation. RESULTS: The majority of samples revealed a VEGFR1 (98%),VEGFR2 (80%),VEGFR3 (67%),PDGFRα (82%) and PDGFRβ(82%) expression,whereas only 62% exhibited an EGFR1 expression. 78% of cancers expressed at least four out of six RTKs. While VEGFR1-3 and PDGFRα revealed a predominantly cytoplasmatic staining in tumor cells,accompanied by an additional nuclear staining for VEGFR3 ,EGFR1 was almost exclusively detected on the membrane of tumor cells. PDGFRβ was restricted to stromal pericytes,which also depicted a PDGFRα expression.receptor-tyrosine-kinases coexpression in gastric adenocarcinoma and might therefore encourage an application of multiple-target RTK-inhibitors within a combination therapy.	Daniel Drescher Markus Moehler Ines Gockel Kirsten Frerichs Annett Müller Friedrich Dünschede Thomas Borschitz Stefan Biesterfeld Martin Holtmann Thomas Wehler Andreas Teufel Kerstin Herzer Thomas Fischer Martin R Berger Theodor Junginger Peter R Galle Carl C Schimanski	2007	World Journal of Gastroenterology2007，13，26：	4
2	Development of high performance multifilamentary Nb-Ti-Ta superconductor for LHC insertion quadrupoles 显示文摘	Lee P J Fischer C M Larbalestier D C	1999	IEEE Trans Applied Superconductivity1999，9，2：	1
3	Parturition at term:parallel increases in interleukin-8 and proteinase concentrations and neutrophil count in the lower uterine segment显示文摘	Winkler M Fischer D C Ruck P	1999	Hum Reprod1999，14，：	1
4	Ubiquitin-conjugating enzyme E2-25K increases aggregate formation and cell death inpolyglutamine diseases显示文摘	de Pril R Fischer D F Roos R A C	2007	Mol Cell Neurosci2007，34，：	1
5	Shading and the growth and photosynthetic responses of Ammann/a coccinnea 显示文摘	Gibson K D Fischer A J Foin T C	2001	Weed Re- seareh2001，41，：	1
6	Knowledge interactions between universities and industry in Austria:sectoral patterns and determinants显示文摘	Schartinger D Rammer C Fischer M M		0，，03：	1
7	Event-related potentials (MMN and novelty P3) in permanent vegetative or minimally conscious states显示文摘	Fischer C Luaute J Morlet D	2010	Clin Neurophysiol2010，121，7：	1
8	Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticold receptor activation 显示文摘	CROCHEMORE C MICHAELIDIS TM FISCHER D	2002	FASEB J2002，16，8：	1
9	SpyGlass : A Wireless Sensor Network Visualizer 显示文摘	Buschmann C Pfisterer D Fischer S	2005	ACM SIGBED Review2005，2，1：	1
10	Novelty P3 elicited by the subject's own name in comatose patients显示文摘	Fischer C Dailler F Morlet D	2008	Clin Neurophysiol2008，119，：	1
11	Adnexal masses in pregnancy显示文摘	Fischer D C Van der Putten H W	2003	Onkologie2003，26，：	1
12	Novelty P3 elicited by the subject's own name in comatose patients显示文摘	Fischer C Dailler F Morlet D	2008	Clin Neurophysiol2008，119，10：	1
13	Mismatch nagativity and N100 in comatose patients显示文摘	Fischer C Morlet D Giard MH	2000	Audiol Neurootol2000，，34：	1
14	Selection and optimization of microbial hosts for biofuels production 显示文摘	Fischer C R Klein-Mareuschamer D Stephanopoulos G	2008	Metab Eng2008，10，6：	1
15	DLR's robotics technologies for on-orbit servicing 显示文摘	HIRZINGER G LANDZETTEL K ADZETTEL K BRUNNER B FISCHER M PREUSCHE C REINTSEMA D ALBU-SCHAFFER A SCHRE1BER G STE1NMTZ B-M	2004	Advanced Robotics2004，18，2：	1
16	Expression of the transcriptional coregulator FHL2 in human breast cancer: a clinicopathologic study显示文摘	Gabriel B Fischer D C Orlowska V M	2006	J Soc Gynecol Investig2006，13，1：	1
17	Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies显示文摘	Stoger E Vaquero C Tortes E Sack M Nicholson L Drossard J Williams S Keen D Perrin Y Christou P and Fischer R	2000	Plant Molecular Biology2000，42，：	1
18	Treatment of hemophagocytic lymphohistiocytosis with chemotherapy and bone marrow transplantation:a single center study of 22 cases显示文摘	Blanche S Caniglia M Girault D Landman J Griscelli C Fischer A	1991	Blood1991，78，1：	1
19	Shear-induced coa- lescence of oil-in-water Picketing emulsions 显示文摘	Whitby C P Fischer F E Fomasiero D	2011	Journal of Colloid and Interface Science2011，361，1：	1
20	Determination of complexation equilibria of macromolecules with small molecules by means of size exclusion chromatography 显示文摘	Fischer C H Berek D Macko T	1994	Polymer Bulletin1994，33，：	1

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