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| 1 | Prophylactic transcatheter arterial embolization reduces rebleeding in non-variceal upper gastrointestinal bleeding: A meta-analysis显示文摘BACKGROUND Despite the improvement in the endoscopic hemostasis of non-variceal upper gastrointestinal bleeding(NVUGIB),rebleeding remains a major concern.AIM To assess the role of prophylactic transcatheter arterial embolization(PTAE)added to successful hemostatic treatment among NVUGIB patients.METHODS We searched three databases from inception through October 19th,2020.Randomized controlled trials(RCTs)and observational cohort studies were eligible.Studies compared patients with NVUGIB receiving PTAE to those who did not get PTAE.Investigated outcomes were rebleeding,mortality,reintervention,need for surgery and transfusion,length of hospital(LOH),and intensive care unit(ICU)stay.In the quantitative synthesis,odds ratios(ORs)and weighted mean differences(WMDs)were calculated with the random-effects model and interpreted with 95%confidence intervals(CIs).RESULTS We included a total of 3 RCTs and 9 observational studies with a total of 1329 patients,with 486 in the intervention group.PTAE was associated with lower odds of rebleeding(OR=0.48,95%CI:0.29–0.78).There was no difference in the 30-d mortality rates(OR=0.82,95%CI:0.39–1.72)between the PTAE and control groups.Patients who underwent PTAE treatment had a lower chance for reintervention(OR=0.48,95%CI:0.31–0.76)or rescue surgery(OR=0.35,95%CI:0.14–0.92).The LOH and ICU stay was shorter in the PTAE group,but the difference was non-significant[WMD=-3.77,95%CI:(-8.00)–0.45;WMD=-1.33,95%CI:(-2.84)–0.18,respectively].CONCLUSION PTAE is associated with lower odds of rebleeding and any reintervention in NVUGIB.However,further RCTs are needed to have a higher level of evidence. | Eszter Boros Zoltán Sipos Péter Hegyi Brigitta Teutsch Levente Frim Szilárd Váncsa Szabolcs Kiss FanniDembrovszky Eduard Oštarijaš Andrew Shawyer Bálint Erőss | 2021 | World Journal of Gastroenterology2021，27，40： | 2 |
| 2 | Concurrent Chiari decompres- sion and spinal cord untethering in children: feasibility in a small case series显示文摘 | Gluncic V Turner M Frim D | 2011 | Acta Neuroebir2011，153，1： | 1 |
| 3 | Adjustable shunt valve repro - gramming at home: safety and feasibility显示文摘 | Sikorski C W Rosen D S Frim D M | 2007 | Neurosurgery2007，60，2： | 1 |
| 4 | Effects of posterior fossa decompression with and without duraplasty on Chiari malformation associated hydromyelia显示文摘 | Munshi I Frim D Stine R | 2000 | Neurosurgery2000，46，6： | 1 |
| 5 | Effects of posterior fossa decompression with and without duraplasty on ehiari malformation associated hydromyelia显示文摘 | Munshi I Frim D Stine R | 2000 | Neurosurgery2000，46，： | 1 |
| 6 | Seizure anticipation in pediatric epilepsy:use of Kolmogorov entropy显示文摘 | Van Drongelen W Nayak S Frim DM | 2003 | Pediatrik Neurologic2003，29，3： | 1 |
| 7 | Local protective effects of nerve growth factor-secreting fibroblasts against excitotoxic lesions in the rat striatum显示文摘 | Frim DM Short MP Rosenberg WS | 1993 | J Neurosurg1993，78，2： | 1 |
| 8 | Recurrence of symptoms after Chiari decompression and duraplasty with nonautologous graft materia显示文摘 | Frim RW | 2003 | Pediatr Neurosurg2003，38，4： | 1 |
| 9 | Recurrence of symptoms after Chiari decompression and duraplasty with nonautologous graft material显示文摘 | Rosen DS Wollman R Frim DM | 2003 | Pediatr Neurosurg2003，38，： | 1 |
| 10 | Olig1 is expressed in human oligodendrocytes during maturation and regeneration显示文摘 | OTHMAN A FRIM D M POLAK P | | 0，，06： | 1 |
| 11 | Effects of pos-terior fossa decompression with and without duraplastyon Chiari malformation associated hydromyelia显示文摘 | Munshi I’Frim D Stine-Reyes R ct al | 2000 | Neu-rosurgery2000，46，6： | 1 |
| 12 | Effects of posterior fossa decompression with and without duraplasty on Chiari malfomation associated hydromyelia 显示文摘 | Munshi I Frim D Stine R | 2000 | Neurosurgery2000，46，6： | 1 |
| 13 | Implanted fibroblasts genetically engineered to produce brainderived neurotrophic factor prevent 1-methyl-4- phenylpyridinium toxicity to dopaminergic neurons in the rat显示文摘 | FRIM D M UHLER T A GALPERN W R | 1994 | Proc Natl Acad Sci1994，91，11： | 1 |
| 14 | Effects of posterior fossa decompression with and without duraplasty on Chiari malfomration-associated hydromyelia显示文摘 | Munshi I Frim D Stine-Reyes R | 2000 | Neurosurgery2000，46，6： | 1 |
| 15 | Local protective effects of nerve growth factor-secreting fibroblasts against excitotoxic lesion in the rat striatum显示文摘 | Frim DM Short MP Rosenberg WS | 1993 | J Neurosurg1993，78，2： | 1 |
| 16 | Effects of poste- rior fossa decompression with and withoutduraplasty on Chiari malformation-associated hydromyelia 显示文摘 | MUNSHI I FRIM D STINE-REYES R | 2000 | Neurosurgery2000，46，6： | 1 |
| 17 | Isintracvrebral schwannoma a developmental tumor of children and young adults?显示文摘 | Frim DM Ogilvy CS Vonsattal JP | 1992 | Peditr Neurosurg1992，18，： | 1 |
| 18 | Effects of posterior fossa decompre ssion with and without duraplasty on Chiari malformation-associated hydromyelia 显示文摘 | Frim D Stine-Reyes R | 2000 | Neurosuegery2000，46，6： | 1 |
| 19 | Treatment of hydrocephalus with third ventriculocisternostomy: outcome and CSF flow pat- terns显示文摘 | Goumnerova L Frim D | 1997 | Pediatric Neurosurgery1997，27，3： | 1 |
| 20 | Effects of posterior fossa de- compression with and without duroplnsty on Chiari malformation--asso- ciated hydromyelia显示文摘 | Munshi L Frim D Stine-Reyes R | 2000 | Neurosurgery2000，46，6： | 1 |
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