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| 1 | Early Yanshanian post-orogenic granitoids in the Nanling region显示文摘 | Peirong Chen Renmin Hua Bangtong Zhang Jianjun Lu Chunfang Fan | 2002 | Science in China Series D: Earth Sciences2002,,8: | 1 |
| 2 | Early Yanshanian post-orogenic granitoids in the Nanling range region: Petrological constraints and geodynamic settings 显示文摘 | Chen Peirong Hua Renmin Zhang Bangtong Lu Jianjun Fan Chunfang | 2002 | Sci China (D)2002,45,8: | 1 |
| 3 | Early Yanshanian post-orogenic granitoids in the Nanling region显示文摘 | Peirong Chen Renmin Hua Bangtong Zhang Jianjun Lu Chunfang Fan | 2002 | Science in China Series D: Earth Sciences2002,,8: | 1 |
| 4 | Synthe- sis of novel ring B abeo-sterol derivatives and their anti- proliferative activities 显示文摘 | Can Chunfang Fan Lianghua Cui Jianguo | 2012 | Steroids2012,77,: | 1 |
| 5 | Early Yanshanian post-orogenic granitoids in the Nanling region显示文摘 | Peirong Chen Renmin Hua Bangtong Zhang Jianjun Lu Chunfang Fan | 2002 | Science in China Series D: Earth Sciences2002,,8: | 1 |
| 6 | Early Yanshanian post-orogenic granitoids in the Nanling region显示文摘 | Peirong Chen Renmin Hua Bangtong Zhang Jianjun Lu Chunfang Fan | 2002 | Science in China Series D: Earth Sciences2002,,8: | 1 |
| 7 | Early Yanshanian post-orogenic granitoids in the Nanling region显示文摘 | Peirong Chen Renmin Hua Bangtong Zhang Jianjun Lu Chunfang Fan | 2002 | Science in China Series D: Earth Sciences2002,,8: | 1 |
| 8 | Impact of apolipoprotein A1 on tumor immune microenvironment, clinical prognosis and genomic landscape in hepatocellular carcinoma显示文摘Background:Current knowledge on apolipoprotein A1(APOA1)in hepatocellular carcinoma(HCC)is fragmented and even contradic-tory.Multi-dimensional analyses are required to comprehensively elucidate its value and underlying mechanism.Methods:We collected 49 RNA-seq datasets,40 cell line types data and 70 scRNA pan-cancer datasets public available,including 17 HCC datasets(1754 tumor samples),and enrolled 73 pairs of HCC tissue and 516 blood samples independently from our clinics.APOA1 impacting on the HCC tumor microenvironment(TME)was analyzed using intensive data mining.Methylation sequencing,flow cy-tometry,quantitative PCR,western blot,immunohistochemistry and clinical chemistry assays were conducted for wet experimental investigation.Results:The APOA1 ontology fingerprint indicated that it played various crucial biological roles in HCC,primarily involved in choles-terol efflux.Consistent findings at histology,serology,and clinical follow-up revealed that high APOA1 was a good prognosis indicator of HCc.Hypermethylation in the APOA1 promoter region was found in clinical samples which is in accordance with the reduction of APOA1 in HCC.The cell cycle,DNA replication,mismatch repair pathways,and tumor cell proliferation were less observed in the HCC APOAihigh subgroup.The favorable immunoregulatory abilities of APOA1 showed interesting findings:a positive correlation between APOA1 and anti-tumor immune cells(NK,CD8+T cells)and a negative association with immune cells exerting immunosuppressive effects,including M2 macrophages.Conclusion:This is an integrative multidimensional exploration of APOA1 using bioinformatics and experiments.Both the prognostic value and anti-tumor effects based on APOA1 panoramic exploration in the HCC TME demonstrate a new potential clinicai target for HCC assessment and intervention in the future. | Ying Wang Shipeng Chen Xiao Xiao Fan Yang Jinhan Wange Hui Zong Yuzhen Gao Chenjun Huang Xuewen Xu Meng Fang Xiaoyan Zhang Chunfang Gao | 2023 | Precision Clinical Medicine2023,6,3: | 0 |
| 9 | Sm-Nd isotopic ages of Tiqiushan eclogites in Xinyi region and its geological significance显示文摘GEOLOGICAL scientists have paid much attention to the suture zones formed by collision between the Sino-Korean and Yangtze blocks because of the discovery of the ultrahigh pressue metamorphic (UHPM) rocksfrom northern Jiangsu Province (Su), southern Shandong Province (Lu) and the Dabie Mountains.Although the age of 200-240 Ma is probably the best estimation for UHPM metamorphism in the DabieMountains, the primary intrusive and metamorphic ages of the complex from northern Jiangsu Provincehave not been determined before. Using the Sm-Nd isotopic dating method, our study is aimed at datingthe UHPM metanorphic event of northern Jiangsu Province and researching a probable relation between theUHPM rocks from the Dabie Mountains and the UHPM rocks from northern Jiangsu Province. | WANG Yinxi~(1,2), YANG Jiedong~(1,2), TAO Xiancong~(1,2), GE Ningjie~4, CHEN Peirong~3, FAN Chunfang~3 and LI Jianhua~5 1. Center of Modern Analysis, Nanjing University, Nanjing 210093, China 2. State Key Laboratory for Research of Mineral Deposits, Nanjing University, Nanjing 210093, China 3. Department of Earth Science, Nanjing University, Nanjing 210093, China 4. Department of Earth and Space Sciences, University of Science and Technology of Chian, Hefei 230026, China 5. No.5 Geological Party of Jiangsu Province, Xuzhou 221005, China | 1999 | Chinese Science Bulletin1999,44,S2: | 0 |
| 10 | Scale Breeding and Reproduction Technique of Ficus tikoua Bur.Container Seedlings显示文摘Based on the principle of asexual reproduction,a kind of scale breeding and reproduction technique of Ficus tikoua Bur.container seedlings was explored by using the characteristics of strong adaptability to the environment and fast growth and reproduction.Using non-woven bag as a breeding container for seedlings,the scale breeding and reproduction technique of F.tikoua container seedlings was summarized through the important links of seedling bed construction,seedling collection,soil configuration,container selection,cutting cultivation,field management,and disease and pest control.This technique can achieve differential,massive and sustainable efficient breeding and reproduction of F.tikoua seedlings in a short time. | Tinghong TAN Fan GAO Yang XIAO Mingxing DAI Shunping BAI Shimei LIAO Chaojun FENG Chunfang WU | 2023 | Plant Diseases and Pests2023,14,5: | 0 |