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| 1 | Giant cell interstitial pneumonia: unusual lung disorder and an update显示文摘 | Dai Jinghong Huang Mei Cao Min Miao Liyun Xiao Yonglong Shi Yi Meng Fanqing Cai Hourong | 2014 | Chinese Medical Journal2014，，15： | 7 |
| 2 | Application of T2~*-weighted first-pass perfusion imaging in the diagnosis of breast tumors显示文摘Objective:To study the diagnostic value of T2*-weighted first-pass perfusion imaging in breast tumors.Methods: We analyzed the magnetic resonance imaging(MRI)information along with the pathological and immunohistochemistry re- sults.Magnetic resonance imaging was performed in 28 patients with breast tumor.The time to signal intensity curves were generated according to the T2*-weighted first-pass perfusion imaging.The curve’s maximal signal intensity drop rate and maximal signal intensity decrease time were analyzed and compared with the pathological diagnoses after surgery.Results: Malignant breast lesions showed higher maximal signal intensity drop rate(44.69%±17.07 vs.17.22%±7.49,P<0.001) than benign lesions,but there was no significant difference of maximal signal decrease time between those two lesions(23.94 s±4.92 vs.20.02 s±6.83,P>0.05).Conclusion:The T2*-weighted first-pass perfusion imaging has enough sensitivity and specificity in breast tumor diagnosis. | Xiaoming Zhuang Bing Zhang Bin Zhu Min Xie Xiangshan Fan Fanqing Meng | 2007 | The Chinese-German Journal of Clinical Oncology2007，6，4： | 4 |
| 3 | Comparative proteomics analysis of cytokeratin and involucrin expression in lesions from patients with systemic lupus erythematosus显示文摘得到反常区别的更好的理解或 keratinocytes 的成熟,我们从全身的豺狼座 erythematosus 病人在损害学习了 cytokeratin 和 involucrin 的表示和分发。从全身的豺狼座 erythematosus 和正常的各个控制的二组 10 个标本被二维的胶化电气泳动,集体度谱的蛋白质鉴定,西方的弄污和免疫组织化学分析。我们的结果显示出那角质素 1 (K1 ) 和 K6/K16 的新合成的 /K10 是下面调整的,那 K5/K14, K2e 和 involucrin 是起来调整的。当 K1/10 微弱地被染色时,我们与在正常外皮染色相比发现 involucrin 强烈在更低的表皮的房间层被染色,特别地。另外,我们发现 involucrin 的表示被增加。这些结果暗示一异常早并且终端区别在全身的豺狼座 erythematosus 的外皮上演,它可以与煽动性的 cytokines 在损害的弯屈的愈合的反应期间释放了被联系。 | Sheng Fang Fanqing Zeng Qing Guo | 2008 | Acta Biochimica et Biophysica Sinica2008，40，12： | 4 |
| 4 | A Lipidomic Study of the Effects of N-methyl-N′-nitro-N-nitrosoguanidine on Sphingomyelin Metabolism显示文摘系统生物学是由在一个房间的所有单个部件之中描述相互作用的份量上,生物回答的 asystems 水平理解能在被完成的一个新、很快开发的研究区域。因此,它为生物分子的 requireshigh 产量测量技术例如为 DNA/RNA 和蛋白质的 genomic 和 proteomicapproaches, respectively.Recently,一个新概念, lipidomics,它利用集体 spectrometry (MS ) 为类脂化合物分析的方法,被建议了。用这 lipidomicapproach,鞘磷脂新陈代谢上的 N-methyl-N-nitro-N-nitrosoguanidine (MNNG ) 的效果, sphingolipids 的一个主要的班,被评估。鞘磷脂分子从房间被提取并且由飞行 MS.It 的帮助矩阵的激光解吸附作用电离时间分析了被发现那 MNNGinduced 深刻在鞘磷脂新陈代谢变化,包括某新鞘磷脂种类的外观和也改变的几鞘磷脂种的一些其它,和集中的消失。这被 acidsphingomyelinase (ASM ) 的再分配伴随,在鞘磷脂新陈代谢的一个关键播放器。在另一方面, imipramine, ASM 的一个禁止者,引起了鞘磷脂的累积。它也一起阻止了一些 ASM.Taken 的效果 ofMNNG,以及再分配,这些数据建议 lipidomicapproach 为细胞的类脂化合物的系统的分析是高度有效的新陈代谢。 | Yun HUANG Jing SHEN Ting WANG Yan-Ke YU Fanqing F. CHEN Jun YANG | 2005 | Acta Biochimica et Biophysica Sinica2005，37，8： | 3 |
| 5 | Distribution of serotonin 5-HT_(2A) and 5-HT_7 receptors in the Onuf’s nucleus of the rat spinal cord显示文摘BACKGROUND:Motoneurons from the Onuf’s nucleus of the spinal cord, which innervate the striated muscle of the pelvic floor, play an important role in erection, ejaculation, and urine control. Serotonin (5-hydroxytryptamine, 5-HT) regulates motoneuron activity from the Onuf’s nucleus of the spinal cord. However, few studies exist that describe 5-HT receptor distribution in the Onuf’s nucleus. In addition, the nature of the effects of 5-HT receptor on the innervating striated muscle of the pelvic floor is controversial. OBJECTIVE: To investigate the distribution of serotonin 5-HT2A and 5-HT7 receptors in motoneurons of Onuf’s nucleus in the spinal cord of male rats, and to analyze the relationship of 5-HT2A and 5-HT7 receptor to central modulation of urogenital function. DESIGN, TIME AND SETTING: The neural morphology experiment was performed at the Ultramicro-structure Laboratory of Reproductive Medicine, Basic Medical College, Chongqing Medical University, China from April to December 2007. MATERIALS: Ten adult, Sprague Dawley rats (eight males and two females) were randomly divided into gender control group (n = 4, 50% male and 50% female) and a retrograde tracing group (n = 6, 100% male) Recombinant pseudorabies virus (PRV-152) was provided by Professor LW Enquist from Princeton University, USA. Rabbit anti-5-HT2A and 5-HT7 receptor antibodies were purchased from Diasorin, France. METHODS: In the gender control group, the spinal L5-6 segments were harvested, sliced, and then incubate antibodies specific against 5-HT2A or 5-HT7 receptors for immunohistochemical staining. In the retrograde tracing group, PRV-152 was separately injected into the right ischiocavernosus (ischiocavernosus subgroup, n = 3) and the right external urethral sphincter (external urethral sphincter subgroup, n = 3). Four days after injection, L5-6 segments were harvested, sliced, and incubated with antibodies specific against 5-HT2A or 5-HT7 receptors for double-labeling immunofluorescence staining. MAIN OUTCOME MEASURES: Distribution analysis of 5-HT2A and 5-HT7 receptors in Onuf’s nucleus utilizing optical or laser confocal microscopy. RESULTS: 5-HT2A receptor immunoreactivity was revealed primarily in the medial region of the dorsolateral nucleus of Onuf’s nucleus. 5-HT7 receptor expression was observed in the lateral part of the dorso-lateral nucleus. 5-HT2A and 5-HT7 receptor expressions in the Onuf’s nucleus were significantly greater in male rats, compared to female rats. Double-labeling immunofluorescence demonstrated that 5-HT2A recepto were distributed primarily in the surrounding motoneurons innervating the ischiocavernosus, and 5-HT7 receptors were primarily expressed in motoneurons innervating the external urethral sphincter. CONCLUSION: Motoneurons innervating the ischiocavernosus and external urethral sphincter are located primarily in the medial and lateral region of the dorsolateral nucleus of L5-6 segments. The 5-HT2A receptor-innervating ischiocavernosus may be preferentially involved in the regulation of sexual reflex, and the 5-HT7 receptor-innervating external urethral sphincter may mainly join in regulating micturition reflex. | Fanqing Zeng Chen Xu Ge Xu | 2008 | Neural Regeneration Research2008，3，8： | 3 |
| 6 | Solvothermal preparation and morphological evolution of stannous oxide powders显示文摘 | Guo Neng Li Fanqing | 2001 | Mater Lett2001，48，： | 1 |
| 7 | Preparation of asymmetric Ni:ceramic composite membrane by electroless plating显示文摘 | Xia Changrong Guo Xiaoxia Li Fanqing | | 0，，： | 1 |
| 8 | Lithographic techniques and surface chemistries for the fabrication of PEG-passivated protein microarrays显示文摘 | Kannan Balaji Castelino Kenneth Chen Fanqing Frank | 2006 | Biosensors and Bioelectronics2006，21，10： | 1 |
| 9 | REE bound DNA in natural plant显示文摘 | Yuqi Wang Ping Jiang Fanqing Guo Zhiyong Zhang Jingxin Sun Lei Xu Guoyin Cao | 1999 | Science in China Series B: Chemistry1999，，4： | 1 |
| 10 | REE bound polysaccharides in leaves of Dicranopteris dichotoma by MAA显示文摘 | Yuqi Wang Jingxin Sun Hongmin Chen Fanqing Guo Lei Xu Guoyin Cao | 1998 | Science in China Series B: Chemistry1998，，3： | 1 |
| 11 | PBKα inhibitor impairs AKT phosphorylation and synergizes with novel angiogenesis inhibitor AL3810 in human hepatocellular carcinoma显示文摘Dear Editor,Hepatocellular carcinoma(HCC)is the second leading cause of cancer-related death worldwide with a 5-year survival rate-50-80% after curative treatment,like surgery,targeted therapy plus TACE or RFA or local treatments,immunotherapy,and so on.1 The approval of several angiogenesis inhibitors,such as sorafenib,regorafenib,lenvatinib,and cabozantinib,have shown therapeutic potential for HCC treatment.However,the improvement of overall survival or progression-free survival is still limited based on angiogenesis inhibitor monotherapy at present. | Qin Xie Shuaishuai Chi Yanfen Fanq Yiming Sun Linghua Meng Jian Ding Yi Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 1 |
| 12 | Graph-Based Chinese Word Sense Disambiguation with Multi-Knowledge Integration显示文摘Word sense disambiguation(WSD)is a fundamental but significant task in natural language processing,which directly affects the performance of upper applications.However,WSD is very challenging due to the problem of knowledge bottleneck,i.e.,it is hard to acquire abundant disambiguation knowledge,especially in Chinese.To solve this problem,this paper proposes a graph-based Chinese WSD method with multi-knowledge integration.Particularly,a graph model combining various Chinese and English knowledge resources by word sense mapping is designed.Firstly,the content words in a Chinese ambiguous sentence are extracted and mapped to English words with BabelNet.Then,English word similarity is computed based on English word embeddings and knowledge base.Chinese word similarity is evaluated with Chinese word embedding and HowNet,respectively.The weights of the three kinds of word similarity are optimized with simulated annealing algorithm so as to obtain their overall similarities,which are utilized to construct a disambiguation graph.The graph scoring algorithm evaluates the importance of each word sense node and judge the right senses of the ambiguous words.Extensive experimental results on SemEval dataset show that our proposed WSD method significantly outperforms the baselines. | Wenpeng Lu Fanqing Meng Shoujin Wang Guoqiang Zhang Xu Zhang Antai Ouyang Xiaodong Zhang | 2019 | Computers, Materials & Continua2019，，7： | 1 |
| 13 | Isolation and characterization of exopolysaccharide with immunomodulatory activity from fermentation broth of Morchella conica 显示文摘 | Su Chaoan Xu Xiaoyan Liu Deyun Wu Ming Zeng Fanqing Zeng Mengyao Wei Wei Jiang Nan Luo Xia | 2013 | DA- RU Journal of Pharmaceutical Sciences2013，21，： | 1 |
| 14 | Growth of Cadmium Mercury Thiocyanate Dimethyl-sulphoxide Single Crystal for Laser Frequency Doubling显示文摘 | Guo Shiyi Yuan Duorong Xu Dong Zhang Guanghui Sun Suoying Meng Fanqing Wang Xinqiang Jiang Xuening Jiang Minhua Sun Daliang Yu Xiling | 2000 | Progress in Crystal Growth and Characterization of Materials2000，，： | 1 |
| 15 | Effect of pH, Ionic Strength, Temperature and Humic Substances on the Sorption of Ni( Ⅱ ) to Na-Attapulgite显示文摘 | FanQ H Shao D D Lu Y | 2009 | Chem Eng J2009，150，： | 1 |
| 16 | The influence of boron content on the structural and electrochemical properties of the La 15 Fe 77 B 8 -type hydrogen storage alloy显示文摘 | Li Wang Huizhong Yan Wei Xiong Baoquan Li Jin Li Fanqing Kong | 2014 | Journal of Power Sources2014，，： | 1 |
| 17 | NMR-Spectroscopy for nontargeted screening and simultaneous quantification of health-relevant compounds in foods:the example of melamine显示文摘 | Lachenmeier D W Humpfer E Fanq F | 2009 | J Agric Food Chem2009，57，16： | 1 |
| 18 | Preparation of asymmetric Ni: ceramic composite membrane by electroless plating 显示文摘 | Xia Changrong Guo Xiaoxia Li Fanqing | 2001 | Colloid Surf A2001，179，23： | 1 |
| 19 | Kidins220/ARMS contributes to airway in- flammation and hyper-responsiveness in OVA-sensitized mice 显示文摘 | Ni X Li X Fanq X | 2011 | Respir Physiol Neurobiol2011，175，1： | 1 |
| 20 | Solvothermal growth of vaterite in the presence of ethylene glycol, 1,2-propanediol and glycerin显示文摘 | Qing Li Yi Ding Fanqing Li Bo Xie Yitai Qian | 2002 | Journal of Crystal Growth2002，，1： | 1 |
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