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| 1 | Soil Organic Matter Dynamics Along a Vertical Vegetation Gradient in the Gongga Mountain on the Tibetan Plateau显示文摘Our knowledge about soil organic matter (SOM) dynamics is limited although this is an important issue in the study of responses of ecosystems to global climate changes. Twelve sampling plots were set up every 200 m from 1 700 to 3 900 m along the vertical vegetation gradient along the east slope of Gongga Mountain. Samples were taken from all 12 plots for SOM content measurement, although only 5 of the 12plots were subjected to radiocarbon measurements. A radiocarbon isotope method and a time-dependent model were used to quantify the SOM dynamics and SOM turnover rates along the vertical vegetation gradient. The results showed that the SOM turnover rate decreased and turnover time increased with soil depth for all vegetation types. The litter layer turnover rates presented a clear trend along the gradient. The litter layer turnover rates decreased with an increase in elevation, except that the litter layer turnover rate of mixed forest was higher than that of evergreen forest. Climatic factors, such as temperature and precipitation,were the main factors influencing the surface soil carbon dynamics. The turnover rates of the subsoil (including the A, B, and C horizons in the soil profiles) along the vertical gradient had no clear trends. The SOM of subalpine shrub and meadow turned over more slowly than that of the forest types in almost all soil horizons. The characteristic of short roots distributing in the upper part of the soil profile leads to different SOM dynamics of shrub and meadow compared with the forest types. Coniferous and mixed forests were susceptible to carbon loss from the young carbon pool, but their long and big roots resulted in high △14C values of the deep soil profiles and increased the input of young carbon to the deep soil. In evergreen forest,the carbon cumulative ability from the B horizon to the C horizon was weak. The different vegetation types,together with their different modes of nutrient and carbon intake, may be the mechanism conditioning the subsoil organic matter dynamics. | LinWANG HuaOUYANG Cai-PingZHOU FengZHANG Ming-HuaSONG Yu-QiangTIAN | 2005 | Journal of Integrative Plant Biology2005，47，4： | 17 |
| 2 | Changes of number of cells expressing proliferation and progenitor cell markers with age in rabbit intervertebral discs显示文摘在 intervertebral 磁盘(IVD ) 以内的正常新生进程的基本知识对内在的生物学的理解重要。在 IVD 的祖先和干细胞的存在被验证了。然而,有年龄的祖先和干细胞的数字的变化仍然是未知的。在这研究,房间增长和祖先房间变化有在从二不同年龄的兔子的 IVD 房间的年龄的标记用流动 cytometry, immunohistochemistry,即时聚合酶链反应,和西方的污点分析被调查。原子抗原(PCNA ) 为增长被选择为一个标记的增殖的房间,和 Notch1, Jagged1, C 工具包, CD166 被选择为干细胞标记。房间周期分析证明在小兔子的 G2/M 阶段的那个房间数字比成熟兔子的显著地高。染色的 Immunohistochemical 在年轻、成熟的体环 fibrosus (AF ) 表明了 PCNA, C 工具包, CD166, Notch1,和 Jagged1 的表示。在小兔子的这些房间标记的蛋白质表情都比在成熟兔子的那些显著地高。PCNA 的表示层次, CD166, C 工具包, Jagged1 在 AF,和 PCNA 是显著地更高的,在从小兔子的原子核 pulposus 的 C 工具包比那些从成熟兔子。这些调查结果证明增长和祖先房间在兔子 IVD 和在兔子 IVD 房间与年龄表示增长和祖先房间标记减少的房间的数字存在。被设计维持内长的祖先房间并且刺激他们的增长的方法能在阻止或禁止退化圆盘疾病是成功的。 | Miersalijiang Yascn Qinming Fei JianZhang WilliamCHutton JianDong XiaoxingJiang FengZhang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，5： | 14 |
| 3 | GA_3和kinetin在低温下对玉米和大豆种子萌发及幼苗发育影响的研究(英文)显示文摘本文在控制温度条件下,研究了GA_3和kinetin在低温条件下对玉米和大豆种子萌发及幼苗发育的影响.结果表明,在萌发适宜温度25℃条件下两种药剂处理的效果均不显著,但在15℃和10℃较低温度条件下两种药剂对玉米和大豆种子萌发有明显促进作用,而且在10℃温度下药剂处理的效果好于在15℃温度下.在10℃低温条件下,对玉米和大豆种子萌发及幼苗发育最有效的处理是0.01mM GA_3和0.005 mM kinetin. | 王庆祥 吕桂兰 FengZhang DonaldL.Smith | 1999 | 作物学报1999，25，3： | 12 |
| 4 | Protective effects of Rheum tanguticum polysaccharide against hydrogen peroxide-induced intestinal epithelial cell injury显示文摘AIM: To describe the effect of Rheum tanguticum polysaccharide (RTP) on hydrogen peroxide-induced human intestinal epithelial cell injury.METHODS: Hydrogen peroxide (100 μmol/L) was introduced to induce human intestinal epithelial cell injury.Cells were pretreated with RTP (30,100,300 μg/mL) for 24 h before exposure to hydrogen peroxide. Cell viability was detected by MTr assay and morphological observation.Acridine orange staining and flow cytometry were performed to assess cell apoptosis. Lactate dehydrogenase (LDH) activity, production of malondialdehyde (MDA) and superoxide dismutase (SOD) activity were measured by spectrophotometry with corresponding assay kits.RESULTS: Following exposure to H2O2, a marked decrease in cell survival and SOD activity, increased production of MDA, LDH leakage and cell apoptosis were found.Pretreatment of the cells with RTP could significantly elevate cell survival, SOD activity and decrease the level of MDA, LDH activity and cell apoptosis.CONCLUSION: RTP may have cytoprotective and antioxidant effects against H2O2-induced intestinal epithelial cell injury by inhibiting cell apoptosis and necrosis. This might be one of the possible mechanisms of RTP for the treatment of ulcerative colitis in rats. | Lin-NaLiu Qi-BingMei LiLiu FengZhang Zhen-GuoLiu Zhi-PengWang Ru-TaoWang | 2005 | World Journal of Gastroenterology2005，11，10： | 11 |
| 5 | X-box-binding protein 1-modified neural stem cells for treatment of Parkinson's disease显示文摘X-box-binding protein 1-transfected neural stem cells were transplanted into the right lateral ventricles of rats with rotenone-induced Parkinson's disease. The survival capacities and differentiation rates of cells expressing the dopaminergic marker tyrosine hydroxylase were higher in X-box-binding protein 1-transfected neural stem cells compared to non-transfected cells. Moreover, dopamine and 3,4-dihydroxyphenylacetic acid levels in the substantia nigra were significantly increased, α-synuclein expression was decreased, and neurological behaviors were significantly ameliorated in rats following transplantation of X-box-binding protein 1-transfected neural stem cells. These results indicate that transplantation of X-box-binding protein 1-transfected neural stem cells can promote stem cell survival and differentiation into dopaminergic neurons, increase dopamine and 3,4-dihydroxyphenylacetic acid levels, reduce α-synuclein aggregation in the substantia nigra, and improve the symptoms of Parkinson's disease in rats. | Lihui Si Tianmin Xu Fengzhang Wang Qun Liu Manhua Cui | 2012 | Neural Regeneration Research2012，7，10： | 6 |
| 6 | Heme oxygenase-1 alleviates ischemia/reperfusion injury in aged liver显示文摘AIM: To investigate if ischemia/reperfusion (I/R) injury in aged liver could be alleviated by heme oxygenase-1 (HO-1).METHODS: Three groups of SD rats (16 mo old) were studied. Group 1: control donors received physiological saline 24 h before their livers were harvested; group 2: donors were pretreated with hemih 24 h before their livers were harvested; and group 3: donors received hemin 24 h before their livers were harvested and zinc protoporphyrin (ZnPP,HO-1 inhibitor) was given to recipients at reperfusion. The harvested livers were stored in University of Wisconsin solution (4 ℃) for 6 h, and then transplanted to syngeneic rats. Serum glutamic oxaloacetic transaminase (SGOT),apoptotic cells, and apoptotic gene were measured 3, 6,12, 24, 48 h after reperfusion. We measured the apoptotic index by TUNEL, determined the expression of antiapoptotic Bcl-2 and proapoptotic (caspase-3) gene products by Western blot.RESULTS: After 3, 6, 12, 24, and 48 h of reperfusion, the SGOT levels (584.4±85.8 u/L, 999.2±125.2 u/L, 423.4±161.3u/L, 257.8±95.8 u/L, and 122.4±26.4 u/L) in hemin group were significantly (all P<0.05) lower than those in saline group (1082.2±101.2 u/L, 1775.2±328.3 u/L, 840.4±137.8 u/L,448.6±74.3 u/L, and 306.2±49.3 u/L). Liver HO-1 enzymatic activity correlated with beneficial effects of hemin and deleterious effects of adjunctive ZnPP treatment. Markedly less apoptotic (TUNEL+) liver cells 3, 6, 12, 24, and 48 h after reperfusion (5.16±0.73, 10.2±0.67, 9.28±0.78, 7.14±1.12,and 4.78±0.65) (P<0.05) could be detected in hemin liver grafts, as compared to controls (7.82±1.05, 15.94±1.82,11.67±1.59, 8.28±1.09, and 6.36±0.67). We detected the increased levels of Bcl-2 (1.5-fold) expression and compared with saline controls. These differences were most pronounced at 12 h after transplantation. In contrast, an active form of proapoptotic caspase-3 (p20) protein was found to be 2.9-fold lower at 24 h in hemin-pretreated group, as compared to saline liver transplant controls.CONCLUSION: HO-1 overexpression can provide potent protection against cold I/R injury. This effect depends, at least in part, on HO-1-mediated inhibition of antiapoptotic mechanism. | Xue-HaoWang KeWang FengZhang Xiang-ChengLi JunLi Wei-De JunGuo Xiao-FengQian YeFan | 2005 | World Journal of Gastroenterology2005，11，5： | 6 |
| 7 | Mea6 controls VLDL transport through the coordinated regulation of COPil assembly显示文摘 | Yaqing Wang Liang Liu Hongsheng Zhang Junwan Fan FengZhang Mei Yu Lei Shi Lin Yang Sin Man Lam Huimin Wang Xiaowei Chen Yingchun Wang Fei Gao Guanghou Shui Zhiheng Xu | 2016 | Cell Research2016，26，7： | 4 |
| 8 | Aging Strengthening in Rapidly Solidified Cu-Cr-Sn- Zn Alloy显示文摘It is known that the strength of alloys can be successfully improved by rapid solidification. The paper presents a process where Cu-Cr-Sn-Zn lead frame alloy is produced by rapid solidification and aging. The microcrystalline structure of rapidly solidified Cu-Cr-Sn-Zn alloy is smaller grain structure examined by optical metallography. The effects of aging processes on the microstructure and properties of the lead frame alloy were investigated. Aged at 500°C for 15 min the fine coherent precipitates Cr distribute in Cu matrix observed by transmission electron microscopy and the properties of hardness and electrical conductivity properties can reach 178HV and 61%IACS, respectively. | Juanhua Su Fengzhang Ren Baohong Tian Pin Liu Qiming Dong | 2009 | Journal of Materials Science & Technology2009，25，2： | 4 |
| 9 | Different surface modification methods and coating materials of zinc metal anode显示文摘Rechargeable aqueous Zn-ion batteries(AZIBs)are one of the most promising energy storage devices for large-scale energy storage owing to their high specific capacity,eco-friendliness,low cost and high safety.Nevertheless,zinc metal anodes suffer from severe dendrite growth and side reactions,resulting in the inferior electrochemical performance of AZIBs.To address these problems,surface modification of zinc metal anodes is a facile and effective method to regulate the interaction between the zinc anode and an electrolyte.In this review,the current challenges and strategies for zinc metal anodes are presented.Furthermore,recent advances in surface modification strategies to improve their electrochemical performance are concluded and discussed.Finally,challenges and prospects for future development of zinc metal anodes are proposed.We hope this review will be useful for designing and fabricating highperformance AZIBs and boosting their practical applications. | Feng Tao Yong Liu Xinyuan Ren Jing Wang Yazhou Zhou Yingjie Miao Fengzhang Ren Shizhong Wei Jianmin Ma | 2022 | Journal of Energy Chemistry2022，31，3： | 4 |
| 10 | Silencing the gene encoding C/EBP homologous protein lessens acute brain injury following ischemia/reperfusion显示文摘C/EBP homologous protein, an important transcription factor during endoplasmic reticulum stress, participates in cell apoptosis mediated by endoplasmic reticulum stress. Previous studies have shown that C/EBP homologous protein mediates nerve injury during Alzheimer's disease, subarachnoid hemorrhage and spinal cord trauma. In this study, we introduced C/EBP homologous protein short hairpin RNA into the brains of ischemia/reperfusion rat models via injection of lentiviral vector through the left lateral ventricle. Silencing C/EBP homologous protein gene expression significantly reduced cerebral infarction volume, decreased water content and tumor necrosis factor-α and interleukin-1β mRNA expression in brain tissues following infarction, diminished the number of TUNEL-positive cells in the infarct region, decreased caspase-3 protein content and increased Bcl-2 protein content. These results suggest that silencing C/EBP homologous protein lessens cell apoptosis and inflammatory reactions, thereby protecting nerves. | Fengzhang Wang Yuan Zhang Chunke He Tingting Wang Qiyan Piao Qun Liu | 2012 | Neural Regeneration Research2012，7，31： | 2 |
| 11 | Study on microstructure and thermodynamics of nacre in mussel shell显示文摘 | Fengzhang Ren Xindi Wan Zhanhong Ma Juanhua Su | 2008 | Materials Chemistry and Physics2008，，1： | 2 |
| 12 | Suppressing interfacial side reactions of zinc metal anode via isolation effect toward high-performance aqueous zinc-ion batteries显示文摘Aqueous zinc(Zn)-ion batteries(AZIBs)are one of the most promising large-scale energy storage devices because of the excellent features of zinc metal anodes,including high theoretical capacity(5,855 mAh·cm^(–3)and 820 mAh·g^(−1)),high safety,and natural abundance.Nevertheless,the large-scale applications of AZIBs are mainly limited by the severe interfacial side reactions of zinc metal anodes,which results in low plating/stripping Coulombic efficiency and poor cycling stability.To address this issue,we report an artificial Ta_(2)O_(5)protective layer on zinc foil(Ta_(2)O_(5)@Zn)for suppressing side reactions during Zn deposition/stripping.The results of density functional theory calculation and experiments indicate that Ta_(2)O_(5)@Zn anode can inhibit the side reactions between the electrolyte and zinc anode through the isolation effect.Benefiting from this advantage,the symmetric cells with Ta_(2)O_(5)@Zn anode delivered an ultralong lifespan of 3,000 h with a low overpotential at 0.25 mA·cm^(−2)for 0.05 mAh·cm^(−2).Furthermore,the full cells consisting of Ta_(2)O_(5)@Zn anode and MnO_(2)or NH_(4)V_(4)O_(10)cathode all present outstanding electrochemical performance,indicating its high reliability in practical applications.This strategy brings new opportunities for the future development of rechargeable AZIBs. | Feng Tao Kaijia Feng Yong Liu Jiangzhuo Ren Yi Xiong Chengbo Li Fengzhang Ren | 2023 | Nano Research2023，16，5： | 2 |
| 13 | AT_1 receptor in rostral ventrolateral medulla mediating blunted baroreceptor reflex in spontaneously hypertensive rats显示文摘AIM: To determine the role of AT1 receptor in the rostral ventrolateral medulla (RVLM) in mediating the blunted baroreceptor reflex in spontaneously hypertensive rats (SHR). METHODS: Intravenous injections of graded doses of phenylephrine (1, 5, 10, 20, and 40μg/kg) increased the blood pressure to elicit the baroreceptor reflex in both SHR and normotensive Wistar rats anesthetized with urethane. The baroreceptor reflex sensitivity (BRS) was determined before and after microinjection of Ang II, losartan, or AT1 receptor antisense oligodeoxynucleotides into the RVLM. AT1 receptor protein level in the RVLM was measured by Western blotting. RESULTS: The BRS was significantly decreased in SHR compared with normal rats. Bilateral microinjection of AT~ receptor antagonist losartan (250 nmol/h) into the RVLM partly reversed the blunted BRS in SHR, but had no significant effect on the BRS in normal rats. Ang II (1.5 nmol/h) significantly inhibited the BRS in normal rats, which was completely abolished by pretreatment with losartan. However, no significant change in the BRS was observed after microinjection of Ang Ⅱ into the RVLM in SHR. Bilateral microinjection of AT1 receptor antisense oligodeoxynucleotides (ASODN) into the RVLM partially recovered the blunted BRS in SHR after 3 h, but no significant change in the BRS was observed in normal rats. The AT1 receptor protein level significantly decreased after administration of ASODN. CONCLUSION: Blockage of AT1 receptor or inhibition of AT1 receptor protein synthesis in the RVLM enhanced the BRS in SHR, suggesting that the enhanced activities of AT1 receptor in the RVLM contribute to the blunted BRS in SHR. | Xin-yaGAO FengZHANG YingHAN Han-junWANG YingZHANG RuiGUO Guo-qingZHU | 2004 | Acta Pharmacologica Sinica2004，25，11： | 2 |
| 14 | Phase transformation in Cu–Cr–Zr–Mg alloy显示文摘 | Juanhua Su Ping Liu Hejun Li Fengzhang Ren Qiming Dong | 2007 | Materials Letters2007，，27： | 2 |
| 15 | PC-407 inhibited proliferation and induced apoptosis in human colon cancer SW-1116 cells显示文摘AIM: To study whether PC-407 [4-[5-naphthyl-3- (trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide] inhibits cell viability and induces apoptosis in human colon cancer SW-1116 cells. METHODS: Inhibition of SW-1116 proliferation was measured by MTT assay. Morphological assessment of apoptosis was performed with fluorescence microscope and electron microscope. DNA fragmentation was visualized by agarose gel electrophoresis.The amount of apoptotic cells was measured by flow cytometry. RESULTS: PC-407 inhibited SW-1116 cell proliferation in a concentration-dependent manner after 3 d of treatment, and the IC5o for PC-407 inhibition of cell number was 16.67±0.17μmol/L. After incubation of SW-1116 cells with PC-407 20μmol/L for 24 h, morphological changes of typical apoptosis were observed by AO/EB staining or transmission electron microscopy. Flow cytometry analysis showed that PC-407 induced apoptosis in SW-1116 cells in a time- and concentration-dependant manner. The agarose gel electrophoresis of DNA revealed a 'ladder' pattern 48 h later. CONCLUSION: PC-407 inhibited proliferation and induced apoptosis in the human colon cancer SW-1116 cell line. | Li-liHAO Qi-bingMEI Bang-leZHANG MinJIA Xiao-qiangLI FengZHANG | 2004 | Acta Pharmacologica Sinica2004，25，11： | 2 |
| 16 | Positive Charges on Lysine Residues of the Extrinsic 18 kDa Protein Are Important to Its Electrostatic Interaction with Spinach Photosystem Ⅱ Membranes显示文摘To determine the contribution of charged amino acids to binding with the photosystem Ⅱcomplex(PSⅡ),the amino or carboxyl groups of the extrinsic 18 kDa protein were modified with N-succinimidyl propionate(NSP)or glycine methyl ester(GME)in the presence of a water-soluble carbodiimide,respectively.Based on isoelectric point shift,4-10 and 10-14 amino groups were modified in the presence of2 and 4 mM NSP,respectively.Similarly,3-4 carboxyl groups were modified by reaction with 100mMGME.Neutralization of negatively charged carboxyl groups with GME did not alter the binding activity of theextrinsic 18 kDa protein.However,the NSP-modified 18 kDa protein,in which the positively charged aminogroups had been modified to uncharged methyl esters,failed to bind with the PSⅡ membrane in the presenceof the extrinsic 23 kDa protein.This defect can not be attributed to structural or conformational alterationsimposed by chemical modification,as the fluorescence and circular dichroism spectra among native,GME-and NSP-modified extrinsic 18 kDa proteins were similar.Thus,we have concluded that the positive chargesof lysyl residues in the extrinsic 18 kDa protein are important for its interaction with PSⅡ membranes in thepresence of the extrinsic 23 kDa protein.Furthermore,it was found that the negative charges of carboxylgroups of this protein did not participate in binding with the extrinsic 23 kDa protein associated with PSⅡmembranes. | Jin-Peng GAO Zhen-Hua YONG FengZHANG Kang-Cheng RUAN Chun-He XU Gen-Yun CHEN | 2005 | Acta Biochimica et Biophysica Sinica2005，37，11： | 2 |
| 17 | Complete Genome Sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04)显示文摘Beijing has been one of the epicenters attacked most severely by the SARS-CoV (severe acute respiratory syndrome-associated coronavirus) since the first patient was diagnosed in one of the city's hospitals. We now report complete genome sequences of the BJ Group, including four isolates (Isolates B J01, B J02, B J03,and B J04) of the SARS-CoV. It is remarkable that all members of the BJ Group share a common haplotype, consisting of seven loci that differentiate the group from other isolates published to date. Among 42 substitutions uniquely identifled from the BJ group, 32 are non-synonymous changes at the amino acid level.Rooted phylogenetic trees, proposed on the basis of haplotypes and other sequence variations of SARS-CoV isolates from Canada, USA, Singapore, and China, gave rise to different paradigms but positioned the BJ Group, together with the newly discovered GD01 (GD-Ins29) in the same clade, followed by the H-U Group (from Hong Kong to USA) and the H-T Group (from Hong Kong to Toronto), leaving the SP Group (Singapore) more distant. This result appears to suggest a possible transmission path from Guangdong to Beijing/Hong Kong, then to other countries and regions. | ShengliBi E‘deQin ZuyuanXu WeiLi JingWang YongWuHu YongLiu ShuminDuan JianfeiHu YujunHan JingXu YanLi YaoYi YongdongZhou WeiLin1 JieWen HongXu RuanLi ZizhangZhang HaiyanSun JinguiZhu ManYu BaochangFan QingfaWu WeiLin2 LinTang Bao’anYang GuoqingLi WenmingPeng WenjieLi TaoJiang YajunDeng BohuaLiu JianpingShi YongqiangDeng WeiWei HongLiu ZongzhongTong FengZhang YuZhang Cui‘eWang YuquanLi JiaYe YonghuaGan JiaJi XiaoyuLi XiangjunTian FushuangLu GangTan RuifuYang BinLiu SiqiLiu SonggangLi JunWang JianWang WuchunCao JunYu XiaopingDong HuanmingYang | 2003 | Genomics, Proteomics & Bioinformatics2003，1，3： | 1 |
| 18 | Rapid evaluation method for power supply capability of urban distribution system based on N- 1 contingency analysis of main-transformers显示文摘 | Luo Fengzhang Wang Chengshan Xiao Jun | 2010 | International Journal of Electrical Power and Energy Systems2010，2，10： | 1 |
| 19 | Phase transformation in Cu–Cr–Zr–Mg alloy显示文摘 | Juanhua Su Ping Liu Hejun Li Fengzhang Ren Qiming Dong | 2007 | Materials Letters2007，，27： | 1 |
| 20 | Sliding Wear Behavior of Copper Alloy Contact Wire Against Copper-Based Strip for High-Speed Electrified Railways显示文摘 | JIA Shuguo LIU Ping REN Fengzhang | 2007 | Wear2007，262，78： | 1 |
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