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29篇 您的检索式：作者名="Florent L"

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	题名	作者	年代	出处	被引量
1	Novel two-step SnOJSnO water-splitting cycle for solar ther- mochemical production of hydrogen 显示文摘	STEPHANE A PATRICE C FLORENT L	2008	International Journal of Hydrogen Energy2008，33，：	1
2	Yersinia pestis YopJ suppresses tumor necrosis factor alpha induction and contributes to apoptosis of immune cells in the lymph node but is not required for virulence in a rat model of Bubonic plague 显示文摘	Nadiue L Florent S Danie L	2006	Infect Immun2006，74，9：	1
3	Molecular basis of human hypertension: role of angiotensinoen显示文摘	Jeunemaitre L Florent S Yuriv K	1992	Cell1992，71，10：	1
4	Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia显示文摘A gain-of-function mutation in the fibroblast growth factor receptor 3 gene(FGFR3)results in achondroplasia(ACH),the most frequent form of dwarfism.Constitutive activation of FGFR3 impairs bone formation and elongation and many signal transduction pathways.Identification of new and relevant compounds targeting the FGFR3 signaling pathway is of broad importance for the treatment of ACH,and natural plant compounds are prime drug candidate sources.Here,we found that the phenolic compound(-)-epicatechin,isolated from Theobroma cacao,effectively inhibited FGFR3’s downstream signaling pathways.Transcriptomic analysis in an Fgfr3 mouse model showed that ciliary mRNA expression was modified and influenced significantly by the Indian hedgehog and PKA pathways.(-)-Epicatechin is able to rescue mRNA expression impairments that control both the structural organization of the primary cilium and ciliogenesis-related genes.In femurs isolated from a mouse model(Fgfr3^(Y367C/+))of ACH,we showed that(-)-epicatechin eliminated bone growth impairment during 6 days of ex vivo culture.In vivo,we confirmed that daily subcutaneous injections of(-)-epicatechin to Fgfr3^(Y367C/+) mice increased bone elongation and rescued the primary cilium defects observed in chondrocytes.This modification to the primary cilia promoted the typical columnar arrangement of flat proliferative chondrocytes and thus enhanced bone elongation.The results of the present proof-of-principle study support(-)-epicatechin as a potential drug for the treatment of ACH.	Ludovic Martin Nabil Kaci Catherine Benoist-Lasselin Marine Mondoloni Suzanne Decaudaveine Valentin Estibals Maxence Cornille Léa Loisay Justine Flipo Benoît Demuynck Maria de la Luz Cádiz-Gurrea Florent Barbault Salvador Fernández-Arroyo Laurent Schibler Antonio Segura-Carretero Emilie Dambroise Laurence Legeai-Mallet	2022	Bone Research2022，10，1：	1
5	A multidimensional analysis of poverty in China from 1991 to 2006 显示文摘	Kelly L Florent B	2011	Economic Review2011，22，4：	1
6	The production of fine-scale microstructures by rapid annealing显示文摘	Florent L S	2008	Mater Sci Eng A2008，48，3484：	1
7	Acute hepatitis C during the third trimester of pregnancy显示文摘	Florent Gonzalez Michèle-Ange Medam-Djomo Damien Lucidarme Ali Khalil Anne Decoster Denis Houze de L’Aulnoit Bernard Filoche	2006	Gastroenterologie Clinique et Biologique2006，，5：	1
8	Crystal plasticity modeling of slip activity in Ti-6Al-4V under high cycle fatigue loading 显示文摘	Florent Bridier David L Mcdowell Patrick Villechaise	2009	International Journal of Plasticity2009，25，6：	1
9	Properties of diamond underhydrostatic pressures up to 140 GPa 显示文摘	FLORENT 0 PAUL L RENE L	2003	Nature Materials2003，2，：	1
10	Analysis of solar chemical processes for hydrogen production from water splitting thermochemical cycles 显示文摘	Charvin P Stephane A Florent L	2008	Energy Conversion and Management2008，49，6：	1
11	Determination of the phosphorylation level and deamidation susceptibility of equine beta-casein显示文摘	Girardet J M Miclo L Florent S Molle D Gaillard J L		0，，：	1
12	A comparative study of predictive current control schemes for a permanent-magnet synchronous machine drive显示文摘	Florent M Xuefang L Jean Marie R	2009	IEEE Transactions on Industrial Electronics2009，56，7：	1
13	Prenatal and postnatal ciliated hepatic foregut cysts in infants显示文摘	Florent Guérin Rim Hadhri Monique Fabre Danièle Pariente Virginie Fouquet Hélène Martelli Frédéric Gauthier Sophie Branchereau	2010	Journal of Pediatric Surgery2010，，3：	1
14	A robust image watermarking chnique based on quantization noise visibility thresholds显示文摘	FLORENT A V PATRICK L C	2007	Signal Processing2007，87，6：	1
15	Automatic building extraction from DEMs using an object approach and application to the 3D-city modeling显示文摘	Florent L A Marc P B	2008	Isprs Jour- nal of Photogrammetry and Remote Sensing2008，63，3：	1
16	Out-of-core adaptive iso-surface extraction from binary volume data显示文摘	Ricardo U L Florent D Florence D	2014	Graphical Models2014，76，：	1
17	Constant curvature region decomposition of 3D-meshes by a mixed approach vertex-triangle显示文摘	Guillaume L Florent D Atilla B	2004	Journal of WSCG2004，12，13：	1
18	A comparative study of predictive current control schemes for a permanent magnet synchronous machine drive显示文摘	Florent M Xuefang L Retif J	2009	IEEE Transactions on IndustrialElectronics2009，56，7：	1
19	Constant curvature region decomposition of 3D-meshes by a mixed approach vertex-triangle 显示文摘	Guillaume L Florent D Atilla B	2004	Journal of WSCG2004，12，2：	1
20	Determination of the phosphorylation level and deamidation susceptibility of equine β-casein显示文摘	Girardet J M Miclo L Florent S	2006	Proteomics2006，，6：	1

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