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| 1 | Limited sampling model for the analysis of 5 -fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer 显示文摘 | ANTONELLO D P ROMANO D FRANCESCA V | 2002 | Clin Pharmacol Ther2002，72，6： | 1 |
| 2 | Optimized numerical evaluation ofsingular and near-singular potential integrals involving junctionbasis functions显示文摘 | Francesca V Wilton D R | 2011 | IEEE Trans on Antennas and Propaga-tion2011，59，1： | 1 |
| 3 | On the effects of different strategies in modeling balloon-expandable slenting by means of finite element method 显示文摘 | Francesca G Claudio C Lorenza P Luca D V Francesco M | 2008 | Journal of Biomechanics2008，41，： | 1 |
| 4 | Biochemical markers predictingpre-term delivery in symptomatic patients:phosphorylated insu-lin-like growth factor binding protein-1 and fetal fibronectin显示文摘 | Francesca R Anna V Marinella D | 2011 | Arch Gynecol Obsteti2011，284，： | 1 |
| 5 | A molecular study of hippocampus in dogs with convulsion during canine distemper virus encephalitis 显示文摘 | Giulia D Francesca V Sandra S | 2006 | Brain Res2006，1098，1： | 1 |
| 6 | Use of Lactoba- cillus plantarum fermentation products in bread-making to prevent Bacillus subtilis ropy spoilage显示文摘 | FRANCESCA V PALMRIA D B STELLA L L | 2008 | International Journal of Food Microbiology2008，122，3： | 1 |
| 7 | A molecular study of hippocampus in dogs with convulsion during canine distemper virus encephalitis显示文摘 | Giulia D Francesca V Sandra S | 2006 | Brain Res2006，10，9： | 1 |
| 8 | A Time-domain raw signal simulator for interferometrie SAR 显示文摘 | Alessandro M Francesca D V | 2004 | IEEE Trans ON GRS2004，42，9： | 1 |
| 9 | Morphological and ultrastructural aspects of dehydration and rehydration in leaves of Sporobolus stapfianus显示文摘 | Francesca D V Toufik E Roberto C | 1998 | Plant Growth Regulation1998，24，： | 1 |
| 10 | C-reactive protein inischemic stroke: an independent prognostic factor 显示文摘 | NapoliM D Francesca P Bocola V | 2001 | Stroke2001，32，9： | 1 |
| 11 | Morphogenetic,ultra structural and physiological damages suffered by submerged leaves of Elodea canadensis exposed to cadmium显示文摘 | FRANCESCA D V NICOLETTA L R ISABELLA M | | 0，，02： | 1 |
| 12 | A molecular study of hippocampus in dogs with convulsion during canine distemper virus encephalitis显示文摘 | GLIULIS D FRANCESCA V SANDRA S | 2006 | Brain Res2006，10，9： | 1 |
| 13 | Palliative long-term abdominal drains vs large volume paracenteses for the management of refractory ascites in end-stage liver disease显示文摘BACKGROUND Long-term abdominal drains(LTAD)are a cost-effective palliative measure to manage malignant ascites in the community,but their use in patients with end-stage chronic liver disease and refractory ascites is not routine practice.The safety and cost-effectiveness of LTAD are currently being studied in this setting,with preliminary positive results.We hypothesised that palliative LTAD are as effective and safe as repeat palliative large volume paracentesis(LVP)in patients with cirrhosis and refractory ascites and may offer advantages in patients’quality of life.AIM To compare the effectiveness and safety of palliative LTAD and LVP in refractory ascites secondary to end-stage chronic liver disease.METHODS A retrospective,observational cohort study comparing the effectiveness and safety outcomes of palliative LTAD and regular palliative LVP as a treatment for refractory ascites in consecutive patients with end-stage chronic liver disease followed-up at our United Kingdom tertiary centre between 2018 and 2022 was conducted.Fisher’s exact tests and the Mann-Whitney U test were used to compare qualitative and quantitative variables,respectively.Kaplan-Meier survival estimates were generated to stratify time-related outcomes according to the type of drain.RESULTS Thirty patients had a total of 35 indwelling abdominal drains and nineteen patients underwent regular LVP.The baseline characteristics were similar between the groups.Prophylactic antibiotics were more frequently prescribed in patients with LTAD(P=0.012),while the incidence of peritonitis did not differ between the two groups(P=0.46).The incidence of acute kidney injury(P=0.014)and ascites/drain-related hospital admissions(P=0.004)were significantly higher in the LVP group.The overall survival was similar in the two groups(log-rank P=0.26),but the endpoint-free survival was significantly shorter in the LVP group(P=0.003,P<0.001,P=0.018 for first ascites/drain-related admission,acute kidney injury and drain-related complications,respectively).CONCLUSION The use of LTAD in the management of refractory ascites in palliated end-stage liver disease is effective,safe,and may reduce hospital admissions and utilisation of healthcare resources compared to LVP. | Senamjit Kaur Rodrigo V Motta Bryony Chapman Victoria Wharton Jane D Collier Francesca Saffioti | 2024 | World Journal of Hepatology2024，16，3： | 0 |
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