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| 1 | Repression of the Auxin Response Pathway Increases Arabidopsis Susceptibility to Necrotrophic Fungi显示文摘在植物,到 necrotrophic 病原体的抵抗取决于在不同荷尔蒙系统之间的相互影响,例如水杨酸调整的那些酸(SA ) , jasmonic 酸(JA ) ,乙烯,和 abscisic 酸。由 SA 小径发信号的植物生长素的压抑最近被显示贡献抗菌剂抵抗。这里,我们表明表明在刺激植物生长素的 SCF (Skp1CullinF 盒子) ubiquitination 小径展览有缺点的异种 axr1, axr2,和 axr6 的那 Arabidopsis 植物生长素增加的危险性到 necrotrophic 真菌 Plectosphaerella cucumerina 和 Botrytis cinerea。另外,被 SCF-ubiquitin/proteasome 机械通常为移动指向的植物生长素 transcriptional 抑压者 AXR3 的稳定发生在 P 之上。cucumerina 感染。植物生长素运输或 proteasome 功能的药理学抑制各作为在非对待的植物生长素反应异种损害野类型的植物的 necrotroph 抵抗到类似的程度。这些结果建议植物生长素发信号为到 necrotrophic 真菌 P 的抵抗是重要的。cucumerina 和 B。cinerea。SGT1b (编码 HSP90/HSC70 合作女伴的二 Arabidopsis SGT1 基因之一) 在某些抵抗(R) 基因调节到 biotrophic 病原体的植物生长素和 JA 回答和抵抗支持 SCF E3-ubiquitin ligase 建筑群的功能。我们发现 sgt1b 异种对 P 同样抵抗。是的 cucumerina 野类型的植物。相反地, auxin/SCF 发信号异种在到 obligate biotrophic oomycete 的被触发 RPP4 的抵抗是不妥协的, Hyaloperonospora parasitica。因此,在到 oomycetes 的 R 调节基因的抵抗的 SGT1b 的占优势的行动看起来在除帮助 SCF E3-ubiquitin ligases 以外的一个地点。然而, sgt1b axr1 的基因添加在到 H 的危险性的两倍异种。一旦 plantpathogen 相容性被建立, parasitica 建议调停 SCF 的 ubiquitination 贡献限制 biotrophic 病原体殖民。 | Francisco Llorente Paul M usksktt Andrea Sanchez-Vallet Gemma Lopez Brisa Ramos Clara Sanchez-Rodriguez Lucia Jorda Jane Parker Antonio Molina | 2008 | Molecular Plant2008，1，3： | 8 |
| 2 | Eucalyptus grandis plantations:effects of management on soil carbon,nutrient contents and yields显示文摘The expansion of fast-growing tree plantations is a worldwide process,with consequences on soil fertility and soil carbon storage.Disparate results were found on the effects of afforestation with Eucalyptus on soil carbon and other nutrient contents.These discrepancies are usually caused by differences in climate,land use history,soil texture as well as by management related factors such as plantation age,number of rotations,method of establishment(plantation or coppice),harvest residue management and soil preparation.We studied the effect of plantation age,number of rotations,and method of establishment on soils and plant nutrient concentrations in Eucalyptus grandis plantations in NE Argentina on different textured soils.We also determined if yields changed with nutrient variations in soils,and compared soils under plantations to soils under grasslands they replaced.Thirty-one E.grandis stands of different ages,number of rotations and method of establishment were evaluated as well as eight grassland sites.Levels of carbon,nitrogen,phosphorus,potassium,calcium and magnesium were determined for soils and plants.Soil carbon and nitrogen decreased over the number of rotations and were more pronounced in soils with 50-60%sand than soils with>75%sand.Coppice stands showed higher soil carbon and nitrogen levels than plantations,suggesting a negative effect of site preparation before planting on soil nutrient conservation,especially in fine-textured soils.Foliar nutrient concentrations did not follow the trends observed for soil nutrients nor did they reflect nutrient limitations.There was no evidence of decreased yields over successive rotations.Soil carbon and nitrogen contents decrease when grasslands are replaced by E.grandis plantations,and therefore a yield limitation may occur in a medium to long-term frame,especially in stands re-established for short-rotation management.Harvest residue management and site preparation must be specifically designed for improving soil nutrient management. | Diego Martin Sandoval Lopez Marcelo Fabian Arturi Juan Francisco Goya Carolina Alejandra Perez Jorge Luis Frangi | 2020 | Journal of Forestry Research2020，31，2： | 4 |
| 3 | Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience显示文摘AIM To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging(DW-MRI) and glucose metabolism measured by 18 Flabeled fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG-PET/CT) during radiation therapy(RT) for human papillomavirus negative(HPV-) head and neck squamous cell carcinoma(HNSCC).METHODS In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations(DW-MRI at 1.5 T Philips MRI scanner [(n = 24) pre-, during-(2-3 wk), and post-treatment(Tx), and 18F-FDG PET/CT pre- and post-Tx(n = 10)]. All patients received RT. Monoexponential modeling of the DW-MRI data yielded the imaging metric apparent diffusion coefficient(ADC) and the mean of standardized uptake value(SUV) was measured from 18F-FDG PET uptake. All patients had a clinical follow-up as the standard of care and survival status was documented at 1 year.RESULTS There was a strong negative correlation between the mean of pretreatment ADC(ρ =-0.67, P = 0.01) and the pretreatment 18F-FDG PET SUV. The percentage(%) change in delta(?) ADC for primary tumors and neck nodal metastases between pre- and Wk2-3 Tx were as follows: 75.4% and 61.6%, respectively, for the patient with no evidence of disease, 27.5% and 32.7%, respectively, for those patients who were alive with disease, and 26.9% and 7.31%, respectively, for those who were dead with disease.CONCLUSION These results are preliminary in nature and are indicative, and not definitive, trends rendered by the imaging metrics due to the small sample size of HPV- HNSCC patients in a Meixoeiro Hospital of Vigo Experience. | David Aramburu Núnez Antonio Lopez Medina Moisés Mera Iglesias Francisco Salvador Gomez Abhay Dave Vaios Hatzoglou Ramesh Paudyal Alfonso Calzado Joseph O Deasy Amita Shukla-Dave Victor M Munoz | 2017 | World Journal of Radiology2017，9，1： | 2 |
| 4 | Current systematic reviews and meta-analyses of COVID-19显示文摘BACKGROUND Coronavirus disease 2019(COVID-19)has left a significant impact on the world's health,economic and political systems;as of November 20,2020,more than 57 million people have been infected worldwide,with over 1.3 million deaths.While the global spotlight is currently focused on combating this pandemic through means ranging from finding a treatment among existing therapeutic agents to inventing a vaccine that can aid in halting the further loss of life.AIM To collect all systematic reviews and meta-analyses published related to COVID-19 to better identify available evidence,highlight gaps in knowledge,and elucidate further meta-analyses and umbrella reviews that are yet to be performed.METHODS We explored studies based on systematic reviews and meta-analyses with the keyterms,including severe acute respiratory syndrome(SARS),SARS virus,coronavirus disease,COVID-19,and SARS coronavirus-2.The included studies were extracted from Embase,Medline,and Cochrane databases.The publication timeframe of included studies ranged between January 01,2020,to October 30,2020.Studies that were published in languages other than English were not considered for this systematic review.The finalized full-text articles are freely accessible in the public domain.RESULTS Searching Embase,Medline,and Cochrane databases resulted in 1906,669,and 19 results,respectively,that comprised 2594 studies.515 duplicates were subsequently removed,leaving 2079 studies.The inclusion criteria were systematic reviews or meta-analyses.860 results were excluded for being a review article,scope review,rapid review,panel review,or guideline that produced a total of 1219 studies.After screening articles were categorized,the included articles were put into main groups of clinical presentation,epi-demiology,screening and diagnosis,severity assessment,special populations,and treatment.Subsequently,there was a second subclassification into the following groups:gastrointestinal,cardiovascular,neurological,stroke,thrombosis,anosmia and dysgeusia,ocular manifestations,nephrology,cutaneous manifestations,D-dimer,lymphocyte,anticoagulation,antivirals,convalescent plasma,immunosuppressants,corticosteroids,hydroxychloroquine,renin-angiotensin-aldosterone system,technology,diabetes mellitus,obesity,pregnancy,children,mental health,smoking,cancer,and transplant.CONCLUSION Among the included articles,it is clear that further research is needed regarding treatment options and vaccines.With more studies,data will be less heterogeneous,and statistical analysis can be better applied to provide more robust clinical evidence.This study was not designed to give recommendations regarding the management of COVID-19. | Mahmoud Nassar Nso Nso Mostafa Alfishawy Anastasia Novikov Salim Yaghi Luis Medina Bahtiyar Toz Sofia Lakhdar Zarwa Idrees Yungmin Kim Dawa Ongyal Gurung Raheel S Siddiqui David Zheng Mariam Agladze Vikram Sumbly Jasmine Sandhu Francisco Cuevas Castillo Nadya Chowdhury Ravali Kondaveeti Sakil Bhuiyan Laura Guzman Perez Riki Ranat Carlos Gonzalez Harangad Bhangoo John Williams Alaa Eldin Osman Joyce Kong Jonathan Ariyaratnam Mahmoud Mohamed Ismail Omran Mariely Lopez Akwe Nyabera Ian Landry Saba Iqbal Anoosh Zafar Gondal Sameen Hassan Ahmed Daoud Bahaaeldin Baraka Theo Trandafirescu Vincent Rizzo | 2021 | World Journal of Virology2021，10，4： | 2 |
| 5 | Mathematical Morphology Applied to Raster Generalization of Urban City Block Maps 显示文摘 | Manuel Antonio Urena Camara Francisco Javier Ariza Lopez | 2000 | Cartographica2000，37，1： | 1 |
| 6 | Serum Transfen-in Receptor in Children: Usefulness forDetenninating the Nature of Anemia in Infection显示文摘 | Ma Angeles Vazquez Lopez Francisco Lendinez | 2006 | Pediatr Hematol Oneol2006，28，： | 1 |
| 7 | Right Ventricular Ejection Efficiency: A New Echocardiographic Measure of Mechanical Performance in Chronic Pulmonary Hypertension显示文摘 | Angel López‐Candales Francisco R. Lopez Setu Trivedi Jean Elwing | 2014 | Echocardiography2014，，4： | 1 |
| 8 | Review of the El Soplao Amber Outcrop,Early Cretaceous of Cantabria,Spain显示文摘El Soplao 露头,最近在北西班牙(Cantabria ) 发现的早白垩纪琥珀存款,被显示了是有到目前为止在西班牙被发现了的节肢动物包括的琥珀的最大的地点。为琥珀,孢粉学, taphonomy 和那些以前出版了的节肢动物 bioinclusions 补充的 biogeochemistry 此处提供的相关数据。数据的这个集合为 El Soplao 沉积物的琥珀建议至少二植物的来源。? rst (类型 A 琥珀) 强烈支持与 Cheirolepidiaceae 有关的来源,并且第二(类型 B 琥珀) 显示出非特定的针叶树 biomarkers。有 Frenelopsis 的琥珀离开的类型(Cheirolepidiaceae ) 的分子的作文的比较强烈建议一种生物化学的亲密关系和普通植物的起源。初步的 palynologlcal 研究显示地区性的高分类的差异,主要蕨类植物孢子和裸子植物花粉谷物。根据初步的 palynologlcal 数据,这个区域由在副热带的气候下面使适应一个旱季的针叶树森林被住在。在一样的床上与琥珀联系的丰富的 charcoalified 木头是很可能加植物表皮支持了树脂生产和崽,和琥珀的随后的大累积的集中的侵蚀的 paleofires 的证据。另外,第一次在石块记录,在琥珀的 bioinclusions 被报导的 charcoalified 植物纤维。另外的相关 taphonomic 数据在两个都显示长暴露在上的一些琥珀片的表面上是 serpulids 和 bryozoans 的非凡的存在海洋或略有盐味水并且琥珀的一个混合集合。最后,昆虫 bioinclusions 的新调查结果,他们中的一些在石块记录不平常或显示出显著改编,被报导。在结论,为 El Soplao 琥珀露头的起源的一种记录情形被提供。 | María NAJARRO Enrique PENALVER Ricardo PEREZ-DE LA FUENTE Jaime ORTEGA-BLANCO Cesar MENOR-SALVAN Eduardo BARRON Carmen SORIANO Idoia ROSALES Rafael LOPEZ DEL VALLE Francisco VELASCO Fernando TORNOS Véronique DAVIERO-GOMEZ Bernard GOMEZ Xavier DELCLOS | 2010 | Acta Geologica Sinica(English Edition)2010，84，4： | 1 |
| 9 | Laparoscopic total colectomy for colonic inertia: surgical and functional results显示文摘 | George Pinedo Alejandro Jose Zarate Eduardo Garcia Maria Elena Molina Francisco Lopez álvaro Zú?iga | 2009 | Surgical Endoscopy2009，，1： | 1 |
| 10 | The effects of dietary fatty acids on the postprandial triglyceride-rich lipoprotein/apoB48 receptor axis in human monocyte/macrophage cells显示文摘 | Lourdes M. Varela Almudena Ortega-Gomez Sergio Lopez Rocio Abia Francisco J.G. Muriana Beatriz Bermudez | 2013 | The Journal of Nutritional Biochemistry2013，，12： | 1 |
| 11 | Use of a comprehensive panel of biomarkers to predict response to a fluorouracil–oxaliplatin regimen in patients with metastatic colorectal cancer显示文摘 | Maria J Lamas Goretti Duran Emilia Balboa Beatriz Bernardez Manuel Touris Yolanda Vidal Elena Gallardo Rafael Lopez Angel Carracedo Francisco Barros | 2011 | Pharmacogenomics2011，，3： | 1 |
| 12 | DcR1 expression in endometrial carcinomas显示文摘 | Jordi Tarragona Nuria Llecha Maria Santacana Susana Lopez Sonia Gatius David Llobet Xavier Dolcet Victor Palomar-Asenjo Francisco Javier Gonzalez-Tallada Xavier Matias-Guiu | 2010 | Virchows Archiv2010，，1： | 1 |
| 13 | Effects of enzymatic treatments of marigold flowers on lutein isomeric profiles显示文摘 | Francisco D V Octavio Paredes Lopez | 1997 | Agric Food Chem1997，45，： | 1 |
| 14 | Neonatal outcomes of pregnancies affected by haemolytic dis-ease of the foetus and newbornand managed with intrauterinetransfusion:a service evaluation 显示文摘 | Katherine A Birchenall Sebastian E Illanes Francisco Lopez etal | 2013 | Blood Transfus2013，11，4： | 1 |
| 15 | A Neural-network-based Classifier for Large Pattern Recognition显示文摘 | Francisco A Lopez J | 2003 | Neural Network World2003，13，1： | 1 |
| 16 | Single incision versus reduced port splenectomy—searching for the best alternative to conventional laparoscopic splenectomy显示文摘 | Julio Lopez Monclova Eduardo M. Targarona Pablo Vidal Yerald Peraza Francisco Garcia Carlos Rodriguez Otero Luis Pallares Carmen Balague Manuel Trias | 2013 | Surgical Endoscopy2013，，3： | 1 |
| 17 | Determination of phthalate esters in sewage by hemimicells-based solid-phase ex traction and liquid chromatography-mass spectrometry显示文摘 | Francisco J Lopez Jimenez Soledad R | 2005 | Analytica Chemical Acta2005，551，： | 1 |
| 18 | Resistance of olive cuhivars to the defoliating pathotype of Verticillium dahliae 显示文摘 | MARTOS - MORENO Consuelo LOPEZ - ESCUDERO Francisco Javier | 2006 | HortScience2006，41，： | 1 |
| 19 | Soil phosphorus forms as quality indicators of soils under different vegetation covers 显示文摘 | Maria - Belen Turrion Olga Lopez Francisco Lafuente | 2007 | Science of the Total Environment2007，378，1： | 1 |
| 20 | Vertical leaching of contaminants present in cattle slurry:column trails with uncultivated and cultivated soil显示文摘 | Avelino Nunez Delgado Eugenio Lopez Periago Francisco Di-az-Fierros Viqueira | | 0，，36： | 1 |
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