|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reduced antioxidant level and increased oxidative damage in intact liver lobes during ischaemia-reperfusion显示文摘瞄准:为了决定是否增加了,并且详细描述对在老鼠模型上在肝的外科期间测量抗氧化剂防卫合适的方法,肝的血流能引起氧化应力和 hepatocyte 损坏。方法:在戊巴比妥钠昏迷状态,侧面的左和肝的中间的脑叶被抓紧让 45 min 让全部的血供给通过另外的脑叶流动。全部的抗氧化剂地位,谷胱甘肽过氧化物酶和超级氧化物 dysmutase 活动,以及 diene 的集中结合,免费 sulphydril 组织,捐赠 H 能力和肝样品的减少的力量被决定。肝的 Chemiluminescent 紧张也被测量。金属离子(艾尔, Ca, Cu, Fe, Mg, Mn, Zn ) 并且肝的 P 和 S 集中与诱导地联合的血浆被决定光排放分光计和 Se 内容被阴极的的脱衣的 voltammetry 测量。结果:谷胱甘肽过氧化物酶和肝的超级氧化物 dysmutase 活动与在假冒的操作的组观察的那些相比在充血组显著地减少了。全部的抗氧化剂地位的水平在充血组也是显著地更低的。捐赠 H 能力,减少的力量和免费 sulphydril 组集中显示出一样的趋势。重要关联(P<0.05 ) 在非特定的抗氧化剂活动在变化之间被发现。这指向了抗氧化剂防卫系统的同时的活动。当 Ca, Fe, Mg, Se 和 P 离子的层次在充血期间是更高的时,艾尔, Cu, Mn, Zn,和 S 比在假冒的操作的组在充血组是更低的。结论:氧化应力在 ischaemia-reperfusion 期间是为未经触动的肝脑叶的损害的主要因素之一。 | LászlóVáli Gabriella Taba KláraSzentmihályi HedvigFébel TímeaKurucz Zsolt Pallai PéterKupcsulik AnnaBlázovics | 2006 | World Journal of Gastroenterology2006，12，7： | 6 |
| 2 | Gut barrier failure biomarkers are associated with poor disease outcome in patients with primary sclerosing cholangitis显示文摘AIM To assess the prevalence of a panel of serologic markers that reflect gut barrier dysfunction in a mixed cohort of pediatric and adult primary sclerosing cholangitis(PSC) patients.METHODS Sera of 67 PSC patients [median age(range): 32(5-79) years, concomitant IBD: 67% and cirrhosis: 20%] were assayed for the presence of antibodies against to F-actin(AAA Ig A/Ig G) and gliadin(AGA Ig A/Ig G)] and for serum level of intestinal fatty acid-binding protein(I-FABP) by ELISA. Markers of lipopolysaccharide(LPS) exposure [LPS binding protein(LBP)] and various antimicrobial antibodies [anti-OMP Plus Ig A and endotoxin core Ig A antibody(Endo CAb)] were also determined. Poor disease outcome was defined as orthotopic liver transplantation and/or liver-related death during the follow-up [median: 99(14-106) mo]. One hundred and fifty-three healthy subjects(HCONT) and 172 ulcerative colitis(UC) patients were the controls. RESULTS A total of 28.4%, 28.0%, 9% and 20.9% of PSC patients were positive for AAA Ig A, AAA Ig G, AGA Ig A and AGA Ig G, respectively. Frequencies of AAA Ig A and AAA Ig G(P < 0.001, for both) and AGA Ig G(P = 0.01, for both) but not AGA Ig A were significantly higher compared to both of the HCONT and the UC groups. In survival analysis, AAA Ig A-positivity was revealed as an independent predictor of poor disease outcome after adjusting either for the presence of cirrhosis [HR = 5.15(1.27-20.86), P = 0.022 or for the Mayo risk score(HR = 4.24(0.99-18.21), P = 0.052]. AAA Ig A-positivity was significantly associated with higher frequency of antimicrobial antibodies(P < 0.001 for Endo Cab Ig A and P = 0.012 for anti-OMP Plus Ig A) and higher level of the enterocyte damage marker(median I-FABP_(AAA Ig A pos vs neg): 365 vs 166 pg/m L, P = 0.011), but not with serum LBP level. CONCLUSION Presence of Ig A type AAA identified PSC patients with progressive disease. Moreover, it is associated with enhanced mucosal immune response to various microbial antigens and enterocyte damage further highlighting the importance of the gut-liver interaction in PSC. | Tamas Tornai Eszter Palyu Zsuzsanna Vitalis Istvan Tornai David Tornai Peter Antal-Szalmas Gary L Norman Zakera Shums Gabor Veres Antal Dezsofi Gabriella Par Alajos Par Peter Orosz Ferenc Szalay Peter Laszlo Lakatos Maria Papp | 2017 | World Journal of Gastroenterology2017，23，29： | 5 |
| 3 | Microscopic colitis: A retrospective study of clinical presentation in 53 patients显示文摘AIM: To evaluate the relationship between symptoms and microscopic colitis (MC) subtypes: to test whether collagenous colitis (CC) and/or lymphocytic colitis (LC)might be related to both constipation and diarrhea.METHODS: A cohort of patients with independently confirmed typical histopathological changes was investigated. Fifty-three patients with histologically proved MC (46 with CC, 7 with LC) were included. The existence of diarrhea or constipation and the co-existence of autoimmune diseases were also investigated and all data were retrospectively analyzed.RESULTS: Twenty-three (43.39%) of MC patients had chronic constipation (20 in CC, 3 in LC patients). Twentyfour(45.28%) of MC patients had autoimmune disease and the diagnosis of autoimmune disease was always prior to MC. Sjogren's syndrome was associated only with the constipation subgroup.CONCLUSION: The Janus face of MC resembles the subgroups of irritable bowel syndrome. The co-existence of autoimmune diseases and MC is confirmed in both the constipation and diarrhea subgroups. | Zsolt Barta Gabriella Mekkel István Csíp(o|') László Tóth Szabolcs Szakáll Gábor G.Szabó Gyula Bakó Gyula Szegedi Margit Zeher | 2005 | World Journal of Gastroenterology2005，11，9： | 3 |
| 4 | Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype显示文摘 | Gabriella S L Richard L Bradley EK | 2003 | PNAS2003，100，10： | 1 |
| 5 | Weak Hopf Algebras显示文摘 | Gabriella B?hm Florian Nill Kornél Szlachányi | 1999 | Journal of Algebra1999，，2： | 1 |
| 6 | An identification problem in age-Dependent population diffusion显示文摘 | Gabriella D B Alfredo L | 2013 | Numerical Functional Analysis and Optimization2013，34，1： | 1 |
| 7 | Increased bleomycin-induced skin fibrosis in mice lacking the Th1-specific transcription factor T-bet显示文摘 | Gabriella L Denisa M Wu MH | 2006 | Pathobiology2006，73，5： | 1 |
| 8 | Decrease in CD3-negative-CD8dim + and Vδ2/Vγ9 TcR+ peripheral blood lymphocyte counts, low perforin expression and the impairment of natural killer cell activity is associated with chronic hepatitis C virus infection显示文摘 | Gabriella Pár Daniel Rukavina Eckhard R Podack Margit Horányi Júlia Szekeres-Barthó Géza Hegedüs Mária Paál László Szereday Gyula Mózsik Alajos Pár | 2002 | Journal of Hepatology2002，，4： | 1 |
| 9 | Barrett's esophagus:an update显示文摘 | Massimo C Gabriella L Sabrina B | 2003 | Crit Rev Oncol Hematol2003，46，2： | 1 |
| 10 | History andpolicy of biodiesel in Brazil显示文摘 | GABRIELLA P A SANTOS ANDRL SUAREZ PAULO A | 2007 | Energy Policy2007，35，： | 1 |
| 11 | Neuroimmunomodulation in human autoimmune liver disease显示文摘 | Erzsébet Fehér éva Pongor Károly Altdorfer László Kóbori Gabriella Lengyel | 2013 | Cell and Tissue Research2013，，2： | 1 |
| 12 | Sol-Gel processing and characterization of pure and metal-doped SnO2 thin films 显示文摘 | Marco A Luciana M Gabriella L | 2001 | J Am Ceram Soc2001，84，1： | 1 |
| 13 | Antioxidant and prooxidant role of β -carotene in murine normal and tumor thymocytes:effects of oxygen partial pressure显示文摘 | Paola P Chiara L Gabriella C | 1997 | Free Rad Bio Med1997，6，22： | 1 |
| 14 | Integrated enzymatic production of specific structured lipid and phytosterol ester compositions显示文摘 | Gabriella Hellner Enik? Rita T?ke Viviána Nagy Gy?rgy Szakács László Poppe | 2010 | Process Biochemistry2010，，8： | 1 |
| 15 | Human bladder carcinoma is dominated by T - regulatory cells and Thl inhibitory cytokines显示文摘 | Angelica L Christina N Gabriella PW | 2007 | J Urol2007，177，： | 1 |
| 16 | Increased bleomycin-induced skin fibrosis in mice lacking the Thl-specific transcription factor T-bet显示文摘 | Gabriella L Denisa M Wu MI-I | 2006 | Pathobiology2006，73，5： | 1 |
| 17 | Antioxidant capacity of some caramel-containing soft drinks显示文摘 | Oreste V Brenna Elena L M Ceppi Gabriella Giovanelli | 2009 | Food Chemistry2009，115，： | 1 |
| 18 | Soluble urokinase plasminogen activator receptor (suPAR) in the assessment of inflammatory activity of rheumatoid arthritis patients in remission显示文摘 | Gergely Toldi Gabriella Bek? Gabriella Kádár Emília Mácsai László Kovács Barna Vásárhelyi Attila Balog | 2013 | Clinical Chemistry and Laboratory Medicine2013，，2： | 1 |
| 19 | Tournaments and unfair treatment显示文摘 | GABRIELLA S L | 2010 | The Journal of Socio-Economics2010，39，6： | 1 |
| 20 | Factors contributing to enhanced freezing tolerance in wheat during frost hardening in the light 显示文摘 | TIBOR J GABRIELLA S KORNELIA L | 2007 | Phytochemistry2007，12，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员