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| 1 | 建筑遗产的保护——印度的经验及未来的可能性显示文摘1.0遗产
我们的遗产连接着现在与过去的文明。印度的土壤也承载着光荣的历史。尼赫鲁总理曾经这样描述过德里:"在这儿,即使是一块普通的石头也会在我们的耳边轻轻地诉说着这儿的历史,我们呼吸的空气中也充满着文明的尘埃与芬芳的过去。"他对德里的评价也适用于整个印度。 | Jitendra Singh Gaurav Singh Nayana R Singh 吴迪 | 2010 | 建筑与文化2010，，11： | 5 |
| 2 | Understanding the molecular mechanisms of cancer prevention by dietary phytochemicals:From experimental models to clinical trials显示文摘Chemoprevention is one of the cancer prevention approaches wherein natural/synthetic agent(s) are prescribed with the aim to delay or disrupt multiple pathways and processes involved at multiple steps, i.e., initiation, promotion, and progression of cancer. Amongst environmental chemopreventive compounds, diet/beverage-derived components are under evaluation, because of their long history of exposure to humans, high tolerability, low toxicity, and reported biological activities. This compilation briefly covers and compares the available evidence on chemopreventive efficacy and probable mechanism of chemoprevention by selected dietary phytochemicals(capsaicin, curcumin, diallyl sulphide, genistein, green/black tea polyphenols, indoles, lycopene, phenethyl isocyanate, resveratrol, retinoids and tocopherols) in experimental systems and clinical trials. All the dietary phytochemicals covered in this review have demonstrated chemopreventive efficacy against spontaneous or carcinogen-induced experimental tumors and/or associated biomarkers and processes in rodents at several organ sites. The observed anti-initiating, anti-promoting and anti-progression activity of dietary phytochemicals in carcinogen-induced experimental models involve phytochemical-mediated redox changes, modulation of enzymes and signaling kinases resulting to effects on multiple genes and cell signaling pathways. Results from clinical trials using these compounds have not shown them to be chemopreventive. This may be due to our:(1) inability to reproduce the exposure conditions, i.e., levels, complexity, other host and lifestyle factors; and(2) lack of understanding about the mechanisms of action and agent-mediated toxicity in several organs and physiological processes in the host. Current research efforts in addressing the issues of exposure conditions, bioavailability, toxicity and the mode of action of dietary phytochemicals may help address the reason for observed mismatch that may ultimately lead to identification of new chemopreventive agents for protection against broad spectrum of exposures. | Girish B Maru Rasika R Hudlikar Gaurav Kumar Khushboo Gandhi Manoj B Mahimkar | 2016 | World Journal of Biological Chemistry2016，7，1： | 2 |
| 3 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 4 | Part II: Control theory for buffer sizing 显示文摘 | GAURAV R DON T DAMON W | 2005 | ACM SIGCOMM Computer Communica- tion Review2005，35，3： | 1 |
| 5 | Anxiolytie effects of rapid amygdala kindling, and the influence of early life experience in rats 显示文摘 | Jones C Gaurav K O'Briena J Morrisd M Sundra M Michel R | 2009 | Behavioural Brain Research2009，203，1： | 1 |
| 6 | Patient satisfac- tion with dermal fillers and effect on utilization of invasive aesthetic treatment modalities at a university-based cosmetic center显示文摘 | Gaurav Bharti Malcolm W Markslisa R | 2011 | Eur J Plast Surg2011，34，： | 1 |
| 7 | Quantitative structure activity relationship and design of phenyl alkyl ketone derivatives as in- hibitors of phosphodiesterase 4 显示文摘 | Gaurave A Gautam V Singh R | 2014 | Current Enzyme Inhibition2014，10，1： | 1 |
| 8 | Reversible pH-controlled DNA-binding peptide nanotweezers:an in-silico study显示文摘 | Gaurav S Kaushal R David EB | 2008 | Intern J Nanomed2008，3，4： | 1 |
| 9 | Water enhancement of COz conversion on silver in 1-ethyl-3-methylimidazolium tetrafluoroborate 显示文摘 | Brian A R Wei Zhu Gaurav K | 2013 | Journal of The Electrochemical Society2013，160，2： | 1 |
| 10 | 3D-QSAR studies of 4-quinolone derivatives as high-affinity ligands at the benzodiazepine site of brain GABAA receptors显示文摘 | Gaurav A Yadav MR Giridhar R | 2011 | Med Chem Res2011，20，2： | 1 |
| 11 | Phacoemulsification and Modern Cataract Surgery显示文摘 | Eric J Linebarger David R Hardten Gaurav K Shah Richard L Lindstrom | 1999 | Survey of Ophthalmology1999，，2： | 1 |
| 12 | Clinical view on the importance of dendritic cells in asthma 显示文摘 | Gaurav R Agrawal DK | 2013 | Expert Rev Clin Immunol2013，9，10： | 1 |
| 13 | Clinical view on the importance of dendritic cells in asthma显示文摘 | Gaurav R Agrawal DK | 2013 | Expert Rev Clin Immunol2013，9，： | 1 |
| 14 | Patient satisfaction of dermal fillers and effect on utilization of invasive aesthetic treatment modali- ties at a university-based cosmetic center显示文摘 | Gaurav Bharti Malcolm W Markslisa R | 2011 | Eur J Plast Surg2011，34，： | 1 |
| 15 | A new robust reference watermarking seheme based on DWT-SVD显示文摘 | Gaurav B Balasubramanian R | 2009 | Computer Standards ~ Interfaces2009，31，5： | 1 |
| 16 | Computa- tional fluid dynamics modeling for hydrogen ignition in a rapid compression machine 显示文摘 | GAURAV M MANDHAPATI P R CHIHJEN S | 2008 | Combustion and Flame2008，155，： | 1 |
| 17 | Emerging risk factors for cardiovascular diseases:India context显示文摘 | Gupta S Gudapati R Gaurav K | 2013 | India J Endocrinol Metab2013，17，5： | 1 |
| 18 | Emerging risk factors for cardiovascular diseases: Indian context 显示文摘 | Gupta S Gudapati R Gaurav K | 2013 | Indian J Endocrinol Metab2013，17，5： | 1 |
| 19 | Patient satisfaction with dermal fillers and effect on utilization of invasive aesthetic treatment modalities at a university-based cosmetic center 显示文摘 | Gaurav Bharti Malcolm W Markslisa R | 2011 | Eur J Plast Surg2011，34，： | 1 |
| 20 | Expression of the cytoskeleton linker protein ezrin in human caricers 显示文摘 | Benjamin B Gaurav K Ling R | 2007 | Clin Exp Metastasis2007，24，2： | 1 |
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