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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Percutwist: a new single-dilator technique for percutaneous tracheostomy 显示文摘 | Klaus W Diana M Gert S | 2003 | Anesth Analg2003，96，： | 1 |
| 3 | Efficacy and dietary inplications for the use of plant sterol-enriched foods to lower total and low-density lipoprotein cholesterol levels 显示文摘 | Sachiko T Ernst J Gert W | 2000 | Top Clinical Nutrition2000，15，4： | 1 |
| 4 | Push-off force in speed skating 显示文摘 | Koning J J de R W de Boer Gert de Groot and G J van Ingen Schenau | 1987 | Sport Biomech1987，，3： | 1 |
| 5 | Searching for hypothetical proteins: theory and practice based upon original data and literature显示文摘 | GERT L LEILA A S YANG J W | 2005 | Progress in Neurobiology2005，77，： | 1 |
| 6 | The fatty'acids of cal- careous sponges ( Calcarea, Porifera) 显示文摘 | ANDREA S GERT W VOLKER T | 2006 | Chemistry andPhysics of Lipids2006，143，1： | 1 |
| 7 | Muddled or mixed? Inferring palaeoclimate from size distributions of deep-sea clastics显示文摘 | Gert J W Maarten A P | 2003 | Sedimentary Geology2003，162，： | 1 |
| 8 | Human resource management interventions to improve health workers' performance in low and middle income countries显示文摘 | Marjolein D Barend G Gert J W | 2009 | Health Research Policy and Systems2009，7，： | 1 |
| 9 | Reconstruction of the Late Miocene climate of Spain using rodent palaeocommunity successions:an application of end-member modeling显示文摘 | Jan A V D Gert J W | 1999 | Palaeogeogra phy Palaeoclimatology Palaeoecology1999，151，： | 1 |
| 10 | 显示文摘 | Gert W Bos Nicole M | 1999 | J Biomed Mater Res1999，44，： | 1 |
| 11 | Efficacy and dietary inplications for the use of plant sterol-enriched foods to lower total and low-density lipoprotein cholesterol levels显示文摘 | Sachiko T Ernst J Gert W | 2000 | Top Clinical Nutrition2000，15，4： | 1 |
| 12 | LDPE/Mg-A1 Layered Double Hydroxide Nanocomposite: Thermal and Flammability Properties显示文摘 | Francis R C Udo W Gert H | 2007 | Polymer Degradation and Stability2007，92，7： | 1 |
| 13 | Soy protein enhances the Cholesterol-Lowering effect of plant sterol esters in Cholesterol-Fed Hamsters显示文摘 | Yuguang Lin Gert W M Mario A V | 2004 | J Nutr2004，134，： | 1 |
| 14 | Onthe technique of speed skating显示文摘 | Ingen Schenau G J van R W de Boer and Gert de Groo | 1987 | Int Sport Biomech1987，，3： | 1 |
| 15 | Efficacy and dietary implications for the use of plant sterol-enriched foods to lower total and low-density lipopretein cholesterol levels显示文摘 | Sachiko T Ernst J Gert W | 2000 | Top Clinical Nutrition2000，15，4： | 1 |
| 16 | LDPE/Mg-A1 layered double hydroxide nanocomposite: Thermal and flammability properties 显示文摘 | Francis R C Udo W Gert H | 2007 | Polymer Degradation and Stability2007，92，7： | 1 |
| 17 | LDPE/Mg-Al layered double hydroxide nanocomposite: Thermal and flammability properties 显示文摘 | FRANCIS R C UDO W GERT H | 2007 | Polym Degrad Stab2007，92，7： | 1 |
| 18 | Efficacy and dietary implications for the use of plant sterol-enriched foods to lower total and low-demity lipoprotein cholesterol levels显示文摘 | Sachiko T Ernst J Gert W | 2000 | Top Chin Nutr2000，15，4： | 1 |
| 19 | Transcriptional activation of the NF-κB p65 subunit by mitogen- and stress-activated protein kinase-1(MSK1) 显示文摘 | Linda V Gert D W Petra V D | 2003 | EMBO2003，，22： | 1 |
| 20 | In situ gelling hydrogels for pharmaceutical and biomedical applications 显示文摘 | van Tomme S R Storm Gert Hennink W E | 2008 | Int JPharm2008，355，12： | 1 |
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