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| 1 | Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation显示文摘血浆膜(下午) 水泡是发生的动态充满肌动朊的房间伸出,例如在胞质分裂期间,似变形虫的房间活动性和房间附件。用对 21 个肌动朊成核因素的一幅指向的 siRNA 屏幕,我们在房间粘附期间在下午 blebbing 识别一篇小说和人的透明 formin DIAPH3 的必要角色。DIAPH3 的抑制禁止了 blebbing 支持快速的房间传播包含 β 1-integrin。DIAPH3 的多重 isoforms 在 mRNA 和 isoforms, 3 和 7 是然而没导致充满肌动朊的伸出的形成的最大、很丰富的 isoforms 的蛋白质水平上被检测。更确切地说,下午 blebbing 明确地包含了低丰富 isoform 7 由透明自动调整的领域的删除引起了 filopodia 的形成的 isoform 的 1 DIAPH3 和激活。Dimerization 和肌动朊集会活动为由 DIAPH3 isoforms 的特定的房间伸出的正式就职是必要的 1 和 7。我们的数据建议包括 GTPase 有约束力的域的 N 终端区域象它在水泡和 filopodia 之间的伸出活动一样决定了 formin 的 subcellular 本地化。我们建议由 DIAPH3 的 isoform 选择的肌动朊汇编施加特定并且调整的差别在房间粘附和活动性期间工作。 | Jana Stastna Xiaoyu Pan Haicui Wang Alina Kollmannsperger Stefan Kutscheidt Volker Lohmann Robert Grosse Oliver T Fackler | 2012 | Cell Research2012，22，4： | 6 |
| 2 | AJCN:过敏症来袭怎么办?新型益生菌组合疗法显神效显示文摘当进入过敏季节我们可能并不太会拿出手帕或者打喷嚏来预防过敏。日前,一项刊登在国际杂志The American Journal of Clinical Nutrition上的研究报告中。来自佛罗里达大学的研究人员通过研究发现。一种益生菌组合或许能够帮助减轻花粉症的症状。 | Jennifer C Dennis-Wall Tyler Culpepper Carmelo Nieves Jr. Cassie C Rowe Alyssa M Burns Carley T Rusch Ashton Federico Maria Ukhanova Sheldon Waugh Volker Mai Mary C Christman Bobbi Langkamp-Henken | 2017 | 现代生物医学进展2017，17，18： | 3 |
| 3 | Fractional Flow Reserve Versus Angiography for Guiding Percutaneous Coronary Intervention in Patients With Multivessel Coronary Artery Disease显示文摘 | Nico H.J. Pijls William F. Fearon Pim A.L. Tonino Uwe Siebert Fumiaki Ikeno Bernhard Bornschein Marcel van't Veer Volker Klauss Ganesh Manoharan Thomas Engstr?m Keith G. Oldroyd Peter N. Ver Lee Philip A. MacCarthy Bernard De Bruyne | 2010 | Journal of the American College of Cardiology2010，，3： | 2 |
| 4 | Tumor cellvaccinatin for gynecoloical tumor显示文摘 | Volker M Sigrif H Michael S T | 1993 | Hybridoma1993，12，5： | 1 |
| 5 | Pore system characterization in heterogeneous carbonates: An alternative approach to widely-used rock-typing methodologies显示文摘 | Cathy H Volker V Simon T | 2010 | Marine and Petroleum Geology2010，27，4： | 1 |
| 6 | Simultane- ous in situ measurement o{ CO, H20 and gas temper- atures in a full-sized coal-fired power plant by near-in- frared diode lasers显示文摘 | HOLGER T THOMAS F VOLKER E | 2003 | Applied Optics2003，42，12： | 1 |
| 7 | S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction显示文摘 | Pleger S T Remppis A Heidt B Volkers M Chaprun JK Kuhn M | 2005 | Mol Ther2005，12，： | 1 |
| 8 | Translational research in pancreatic ductal adenocarcinoma: current evidence and future concepts显示文摘Pancreatic ductal adenocarcinoma(PDA) is one of the major causes for cancer death worldwide. Treatment of metastatic disease remains challenging as only certain patients benefit from advances made with the intensified chemotherapy regimen folinic acid, irinotecan and oxaliplatin, the epidermal growth factor receptor inhibitor erlotinib or the recently FDA-approved nab-paclitaxel. Up to date, no established approach for prediction of treatment response or specific treatment allocation exists. Translational research was able to identify a number of potential biomarkers that might help to improve the dismal prognosis of PDA by facilitating upfront treatment allocation. This topic highlight is focused on current evidence on potential biomarkers for tumor biology, prognosis and prediction of treatment efficacy. | Stephan Kruger Michael Haas Steffen Ormanns Sibylle Bchmann Jens T Siveke Thomas Kirchner Volker Heinemann Stefan Boeck | 2014 | World Journal of Gastroenterology2014，20，31： | 1 |
| 9 | The fatty'acids of cal- careous sponges ( Calcarea, Porifera) 显示文摘 | ANDREA S GERT W VOLKER T | 2006 | Chemistry andPhysics of Lipids2006，143，1： | 1 |
| 10 | Genomewide transcriptional profiling analysis of adaptation of Bacillus subtilis to high salinity显示文摘 | Steil L Hoffmann T Budde I Volker U Bremer E | 2003 | J Bacteriol2003，185，： | 1 |
| 11 | Glomerular hyperfiltration and the salt paradox in early type 1 diabetes mellitus: a tubulo-cen- tric view显示文摘 | Volker V Blantz R C Scott T | 2003 | JAm Soc Nephrol2003，14，2： | 1 |
| 12 | Metal Complexes of Stable Carbenes显示文摘 | Hermermann W A Weskamp T Volker P W | | 0，，： | 1 |
| 13 | Positron emission tomo- graphy for staging of pediatric sarcoma patients: results of a pro- spective multicenter trial显示文摘 | Volker T Denecke T Steffen I | 2007 | J Clin Oncol2007，25，34： | 1 |
| 14 | Price relationships in the petroleum market: An analysis of crude oil and refined product prices显示文摘 | Asche F Gjberg O Volker T | 2003 | Energy Economics2003，25，3： | 1 |
| 15 | Cardiac adenoviral S100A1 gene delivery rescues failing myocardium 显示文摘 | MOST P PLEGER S T VOLKERS M | 2004 | Journal of Clinical Investigation2004，114，11： | 1 |
| 16 | Casein micelles and their interual structure显示文摘 | Kruif C G Huppertz T Volker S U | | 0，，： | 1 |
| 17 | Thermokinetic investigation of cellulosepyrolysis-impact of initial and final mass onkinetic results 显示文摘 | Volker S Rieckmann T H | 2002 | Joumal of Analytical and Applied Pyrolysis2002，62，2： | 1 |
| 18 | Comparing two dif- ferent arginine vasopressin doses in adanced vasodilatory shock:a randomized,eontrolled,open-labeltrial显示文摘 | Christian T Martin WD Volker W | 2010 | Intensive Care Med2010，36，1： | 1 |
| 19 | Detection of immunotoxicity using T-cell based cytokine reporter cell lines ( 'Cell Chip' ) 显示文摘 | Ringerike T Ulleras E Volker R | 2005 | Toxicology2005，206，2： | 1 |
| 20 | The Native and the heatinduced denatured states of alpha-chymotrypsinogen A:thermodynamic and spectroscopic studies显示文摘 | Chalikian T V Volker J | 1997 | Journal of Molecular Biology1997，274，25： | 1 |
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