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| 1 | Elevated basal intestinal mucosal cytokine levels in asymptomatic first-degree relatives of patients with Crohn's disease显示文摘AIM To determine levels of cytokines incolonic mucosa of asymptomatic first degreerelatives of Crohn’s disease patients.METHODS Cytokines(Interleukin(IL)1-Beta,IL-2,IL-5 and IL-8)were measured using ELISAin biopsy samples of normal looking colonicmucosa of first degree relatives of Crohn’sdisease patients(n = 9)and from normalcontrols(n = 10)with no family history ofCrohn’s disease.RESULTS Asymptomatic first degree relativesof patients with Crohn’s disease had significantlyhigher levels of basal intestinal mucosalcytokines(IL-2,IL-5 and IL-8)than normalcontrols.Whether these increased cytokinelevels serve as phenotypic markers for a geneticpredisposition to developing Crohns diseaselater on,or whether they indicate early(pre-clinical)damage has yet to be further defined.CONCLUSION Asymptomatic first degreerelatives of Crohn’s disease patients have higherlevels of cytokines in their normal-lookingintestinal mucosa compared to normal controls,This supports the hypothesis that increasedcytokines may be a cause or an early event inthe inflammatory cascade of Crohns disease andare not merely a result of the inflammatoryprocess. | Indaram AVK Nandi S Weissman S Lam S Bailey B Blumstein M Greenberg R Bank S | 2000 | World Journal of Gastroenterology2000，6，1： | 8 |
| 2 | 金刚石中的冰-Ⅶ相包裹体:来自地球深部地幔的含水流体证据显示文摘水在地球内部不同圈层的存在形态、分布、含量以及全球水循环一直以来都是固体地球科学研究的前沿热点问题之一。冰-Ⅶ相作为水的一种高压相,目前已经被国际矿物学会认定为一种新矿物。 | Tschauner O Huang S Greenberg E Prakapenka V B Rossman G R Shen A H Zhang D Newville M Lanzirotti A Tait K 张宝华 | 2018 | 矿物岩石地球化学通报2018，37，6： | 4 |
| 3 | 卒中一级预防指南美国心脏协会/美国卒中协会对医疗专业人员的声明显示文摘这份更新版指南旨在为既往无卒中或短暂性脑缺血发作史的人群提供适时的综合性卒中预防循证建议,包括危险因素控制、头颈部动脉粥样硬化性疾病的干预方法以及预防血栓形成和血栓栓塞性卒中的抗栓治疗。此外,本指南还提供了针对遗传和药理学检测以及在其他特殊情况下(包括镰状细胞疾病和卵圆孔未闭)进行卒中预防的建议。 | James F. Meschia Cheryl Bushnell Bernadette Boden-Albala Lynne T. Braun Dawn M. Bravata Seemant Chaturvedi Mark A. Creager Robert H. Eckel Mitchell S.V. Elkind Myriam Fornage Larry B Goldstein Steven M. Greenberg Susanna E. Horvath Costantino Iadecola Edward C. Jauch Wesley S. Moore John A. Wilson 李迪 高一鹭 陈政弘 霍晓川 孙海欣 孙冬玲 茹小娟 江滨 | 2015 | 国际脑血管病杂志2015，23，6： | 4 |
| 4 | Accuracy of biometric formulae for intraocular lens power calculation in a teaching hospital显示文摘AIM: To evaluate the accuracy of three commonly used biometric formulae across different axial lengths(ALs) at one United States Veterans Affairs teaching hospital.METHODS: A retrospective chart review was conducted from November 2013 to May 2018. One eye of each patient who underwent cataract surgery with a monofocal intraocular lens(IOL) was included. The range of postoperative follow-up period was from 3 wk to 4 mo. The Holladay 2, Barrett Universal II, and Hill-Radial Basis Function(Hill-RBF) formulae were used to predict the postoperative refraction for all cataract surgeries. For each formula, we calculated the prediction errors [including mean absolute prediction error(MAE)] and the percentage of eyes within ±0.25 diopter(D) and ±0.5 D of predicted refraction. We performed subgroup analyses for short(AL<22.0 mm), medium(AL 22.0-25.0 mm), and long eyes(AL>25.0 mm).RESULTS: A total of 1131 patients were screened, and 909 met the inclusion criteria. Resident ophthalmologists were the primary surgeons in 710(78.1%) cases. We found no statistically significant difference in predictive accuracy among the three formulae over the entire AL range or in the short, medium, and long eye subgroups. Across the entire AL range, the Hill-RBF formula resulted in the lowest MAE(0.384 D) and the highest percentage of eyes with postoperative refraction within ±0.25 D(42.7%) and ±0.5 D(75.5%) of predicted. All three formulae had the highest MAEs(>0.5 D) and lowest percentage within ±0.5 D of predicted refraction(<55%) in short eyes.CONCLUSION: In cataract surgery patients at our teaching hospital, three commonly used biometric formulae demonstrate similar refractive accuracy across all ALs. Short eyes pose the greatest challenge to predicting postoperative refractive error. | Kevin S Tang Elaine M Tran Allison J Chen David R Rivera Jorge J Rivera Paul B Greenberg | 2020 | International Journal of Ophthalmology(English edition)2020，13，1： | 3 |
| 5 | Intravitreal triamcinolone for refractory diabetic macular edema显示文摘 | Adam Martidis Jay S Duker Paul B Greenberg Adam H Rogers Carmen A Puliafito Elias Reichel Caroline Baumal | 2002 | Ophthalmology2002，，5： | 2 |
| 6 | Habitability of Europa's crust:The role of tidal-tectonic processes显示文摘 | Greenberg R Geissler P Tufts B R | 2000 | Journal of Geophysics Research2000，105，17： | 1 |
| 7 | Morphological char- acterization and spectroscopic studies of the corrosion behavior of tungsten heavy alloys 显示文摘 | Ogundipe A Greenberg B Braida W | 2006 | Corrosion Science2006，48，3： | 1 |
| 8 | Pervaporation of trace chlorinated organics from water through irradiated polyethylene membrane 显示文摘 | Lee G T Krovvidi K R Greenberg D B | 1989 | J Membrane Sci1989，47，： | 1 |
| 9 | Rotavirus vac- cines: recent developments and future considerations 显示文摘 | ANGEL J FRANCO M A GREENBERG H B | 2007 | Nat Rev Microbiol2007，5，7： | 1 |
| 10 | A deoxyribonuclease of Diplococcus pneumoniae soecific for methylated DNA显示文摘 | Lacks S Greenberg B | 1975 | J Biol Chem1975，250，11： | 1 |
| 11 | Rationale and design of a randomized,double-blind,event-driven,multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death,myocardial infarction or stroke in subjects with heart failure and significant coronary artery disease following an exacerbation of heart failure:the COMMANDER HF trial显示文摘 | Zannad F Greenberg B Cleland JG | 2015 | Eur J Heart Fail2015，17，7： | 1 |
| 12 | Deep brain stimulation for psychiatric disorders 显示文摘 | Kopell BH Greenberg B Rezai AR | 2004 | J Clin Neurophysiol2004，21，1： | 1 |
| 13 | Optically switchable thin films: A re- view显示文摘 | Greenberg C B | 1994 | Thin Solid Films1994，251，81： | 1 |
| 14 | Design of a Phase 2b Trial of Intracoronary Administration of AAV1/SERCA2a in Patients With Advanced Heart Failure:The CUPID 2 Trial (Calcium Up-Regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease Phase 2b)显示文摘 | Greenberg B Yaroshinsky A Zsebo KM | 2014 | JACC Heart Fail2014，2，1： | 1 |
| 15 | Energy Choices and Risk Beliefs:Is It Just Global Warming and Fear of a Nuclear Power Plant Accident?显示文摘 | Greenberg M Truelove H B | 2011 | Risk Analysis2011，31，5： | 1 |
| 16 | Human mitochondrial DNA variation and evolution:Analysis of nucleotide sequences form seven individuals显示文摘 | AQUARO C F GREENBERG B D | 1983 | Gentics1983，，103： | 1 |
| 17 | Basic pathogenetic mech- anisms in silicosis: current understanding 显示文摘 | Rimal B Greenberg AK Rom WN | 2005 | Curt Opin Pulm Med2005，11，2： | 1 |
| 18 | Human mitochondrial DNA variationand evolution:analysis of nucleotide sequences from seven individuals显示文摘 | AQUADRO C F GREENBERG B D | 1983 | Genetics1983，103，： | 1 |
| 19 | A theoretical and experimental study of the centrifugal molecular still 显示文摘 | Greenberg D B | 1972 | AIChE1972，18，2： | 1 |
| 20 | Chlorophyll fluorescence as a bioindicator of effects on growth in a- quatic macrophytes from mixtures of polycyclic aromatic hydrocarbons显示文摘 | Marwood C A Solomon K R Greenberg B M | 2001 | Environmental Toxicology and Chemis- try2001，20，4： | 1 |
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