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| 1 | Radiofrequency ablation for treatment of hypersplenism: A feasible therapeutic option显示文摘We present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia. We performed spleen ablation and measured the total spleen and ablated volumes with contrast-enhanced computed tomography and volumetry. No major complications occurred, thrombocytopenia was resolved, and platelet levels remained stable, which allowed for early treatment of the patient's underlying disease. Previous work has shown that splenic radiofrequency ablation is an attractive alternative treatment for hypersplenism induced by liver cirrhosis. We aimed to contribute to the currently sparse literature evaluating the role of radiofrequency ablation(RFA) in the management of hypersplenism. We conclude that splenic RFA appears to be a viable and promising option for the treatment of hypersplenism. | Guilherme Lopes P Martins Joao Paulo G Bernardes Marcello S Rovella Raphael G Andrade Publio Cesar C Viana Paulo Herman Giovanni Guido Cerri Marcos Roberto Menezes | 2015 | World Journal of Gastroenterology2015，21，20： | 17 |
| 2 | Incidence and trends of cardiovascular mortality after common cancers in young adults:Analysis of surveillance, epidemiology and end-results program显示文摘AIM: To describe the incidence of cardiovascular mortality(CVM) in survivors of major cancers and identify its trends over the past two decades. METHODS: We used the surveillance, epidemiology and end-results 19 registry to identify young adults(20-49 years), diagnosed with the following major primary cancers: Lung, breast, liver/intrahepatic bile duct, pancreas, prostate, colorectal, and ovarian from 1990 through 2012 and identified the cumulative incidence of CVM after adjusting for confounding factors. RESULTS: We identified a total of 301923 cancers(breast 173748, lung 38938, colorectal 31722, prostate 22848, ovary 16065, liver 9444, pancreas 9158). A total of 2297(0.8%) of patients had incident CVM. Lung(10-year cumulative CVM 2.4%) and liver(1.73%) cancers had the highest incidence of CVM, while breast(0.6%) and prostate(1.2%) had the lowest CVM mortality, even after multiple adjustments(P < 0.001). Overall, there was a significant improvement in CVM since 1990 [2005-2012 vs 1990-1994, adjusted HR 0.63(0.54-0.72), P < 0.001]. This was driven by improvements in CVM in lung cancers(P = 0.02), breast(P < 0.001), and a trend in ovarian cancer(P = 0.097).There was no statistically significant improvement in CVM among survivors of colorectal, pancreatic, liver, or prostate cancers.CONCLUSION: The risk of CVM differs among different cancers, and is highest among survivors of lung and liver cancers. The incidence of CVM has decreased over the past 2 decades mainly among survivors of lung and breast cancers. | Sadeer G Al-Kindi Guilherme H Oliveira | 2016 | World Journal of Cardiology2016，8，6： | 2 |
| 3 | A multiscale DHI elastic attributes evaluation显示文摘 | Schwedersky G Guilherme V | 2003 | The Leading Edge2003，22，10： | 1 |
| 4 | Thermo-responsive sandwiched-like membranes oflPN-PNIPAAm/PAAm hydrogels 显示文摘 | GUILHERME M R CAMPESE G M RADOVANOVIC E | 2006 | Journal of Membrane Science2006，275，12： | 1 |
| 5 | Voltage SagsCompensation Using a Superconducting Flywheel Ener-gy Storage System 显示文摘 | Rubens A Antonio C Guilherme G | 2005 | IEEE Transactions on AppliedSuperconductivity2005，15，2： | 1 |
| 6 | Carotid artery stenting versus endarterectomy:a systematic review显示文摘 | Amir G Emerson CP Guilherme S | 2012 | Tex Heart Inst J2012，39，47： | 1 |
| 7 | A multiscale DHI elastic attributes evaluation 显示文摘 | Dillon L Schwedersky G Guilherme V | 2003 | The Leading Edge2003，22，10： | 1 |
| 8 | Biosolids and heavy metals in soils显示文摘 | Silveira M L A Alleoni L R F Guilherme L R G | 2003 | Scientia Agricola2003，60，4： | 1 |
| 9 | Contemporary characteristics and outcomes of adults with familial dilated cardiomyopathy listed for heart transplantation显示文摘BACKGROUND Familial dilated cardiomyopathy(FDCM) account for 20%-30% of non-ischemic cardiomyopathies(NICM). Previous published data showed that some patients with FDCM tend to have rapidly progressive disease; however, five-year mortality was not significantly different in the familial and non-familial forms of NICM with optimal medical therapy.AIM To better define the characteristics and clinical outcomes of FDCM patients listed for heart transplantation(HT).METHODS We queried the United Network for Organ Sharing Registry to identify FDCM patients listed for HT between January 2008 and September 2015 and compared them to NICM and ischemic cardiomyopathy(ICM) patients. We included all patients ≥ 18 years old and we separated patients to three groups: FDCM, NICM and ICM. Chi-square test was used to compare between categorical variables, the t-test was used to compare between continues variables, and Cox-proportional hazards model was used to perform time-dependent survival analyses.RESULTS Of the 24809 adults listed for HT, we identified 677 patients(2.7%) with the diagnosis of FDCM. Compared to patients with NICM and ICM, FDCM patients were younger(FDCM 43.9 ± 13.5 vs NICM 50.9 ± 12.3, P < 0.001, vs ICM 58.5 ±8.1, P < 0.001), more frequently listed as status 2(FDCM 35.2% vs NICM 26.5%, P< 0.001), with significantly lower left ventricular assist device(LVAD) utilization(FDCM 18.4% vs NICM 25.1%, P < 0.001; vs ICM 25.6%, P < 0.001), but higher use of total artificial heart(FDCM 1.3% vs NICM 0.6%, P = 0.039; vs ICM 0.4%, P =0.002). Additionally, patients with FDCM were less frequently delisted for clinical deterioration or death and more likely to be transplanted compared to those with NICM [hazard ratio(HR): 0.617, 95% confidence interval(CI): 0.47-0.81; HR: 1.25,95%CI: 1.14-1.37, respectively], and ICM(HR: 0.5, 95%CI: 0.38-0.66; HR: 1.18,95%CI: 1.08-1.3, respectively). There was more frequent rejection among patients with FDCM(FDCM 11.4% vs NICM 9.8%, P = 0.28; vs ICM 8.4%, P = 0.034). One,three, and five post-transplant survival of patients with FDCM(91%, 88% and80%) was similar to those with NICM(91%, 84%, 79%, P = 0.225), but superior to those with ICM(89%, 82%, 75%, P = 0.008), respectively.CONCLUSION End-stage FDCM patients are more likely to be transplanted, more likely to have early rejection, and have similar or higher survival than patients with other cardiomyopathies. | Mohamed Khayata Sadeer G Al-Kindi Guilherme H Oliveira | 2019 | World Journal of Cardiology2019，11，1： | 1 |
| 10 | Effects of 8-Week, Interval-Based Inspiratory Muscle Training and Breathing Retraining in Patients With Generalized Myasthenia Gravis显示文摘 | Guilherme Augusto de Freitas Fregonezi Vanessa Regiane Resqueti Rosa Güell Jesus Pradas Pere Casan | 2005 | Chest2005，，3： | 1 |
| 11 | Cadmium stress in sugar cane callus cultures: Effect on antioxidant enzymes显示文摘 | Ricardo F F Renato R F Guilherme J G P | 2002 | Plant Cell Tissue and Organ Culture2002，71，： | 1 |
| 12 | Arterial distensibility in subjects with white-coat hypertension with and without diabetes or dyslipidaemia: comparison with normotensives and sustained hyper- tensives显示文摘 | Laura R Guilherme G Alejandm S | 2000 | Blood Press Monit2000，5，1： | 1 |
| 13 | A comparison between magnetic resonance angiography at 3 teslas(time-of-flight and contrast-enhanced)and flat-panel digital subtraction angiography in the assessment of embolized brain aneurysms显示文摘 | Guilherme S Nakiri Antonio C Santos Thiago G Abud | 2011 | Clinics(Sao Paulo)2011，66，： | 1 |
| 14 | Bosniak category IIF designation and surgery for complex renal cysts 显示文摘 | REBECCA L MALLEY O GUILHERME G | 2009 | J Urol2009，182，3： | 1 |
| 15 | Seleniumbiofortification and antioxidant activity in lettuce plants fed withselenate and selenite显示文摘 | Ramos S J Faquin V Guilherme L R G | 2010 | Plant Soil and Environment2010，56，12： | 1 |
| 16 | 显示文摘 | Elena L M Barra Guilherme M O Soares Bluma G | 2001 | Synthetic Metals2001，123，3： | 1 |
| 17 | Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2 显示文摘 | Tesz G J Guilherme A Guntur KV | 2007 | J Biol Chem2007，282，19： | 1 |
| 18 | Thermo-responsive sandwiched-like membranes of IPNPNIPAAm/PAAm hydrogels显示文摘 | Guilherme M R Campese G M Radovanovic E | 2006 | J Membrane Sci2006，275，12： | 1 |
| 19 | Selenium biofortification and antioxi- dant activity in lettuce plants fed with selenate and selenite显示文摘 | Ramos S J Faquin V Guilherme L R G | 2010 | Plant Soil and Environment2010，56，12： | 1 |
| 20 | Fluid property discrimination with AVO: a multiscale DHI elastic attributes evalution 显示文摘 | Dillon L Schwedersky G Guilherme V | 2003 | The Leading Edge2003，22，10： | 1 |
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