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14篇 您的检索式：作者名="GUNDA M"

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		题名	作者	年代	出处	被引量
	1	Increased liver stiffness in alcoholic liver disease:Differentiating fibrosis from steatohepatitis显示文摘AIM:To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS).METHODS:We first performed sequential LS analysis before and after normalization of serum transaminases in a learning cohort of 50 patients with ALD admitted for alcohol detoxification. LS decreased in almost all patients within a mean observation interval of 5.3 d. Six patients (12%) would have been misdiagnosed with F3and F4 fibrosis but LS decreased below critical cut-off values of 8 and 12.5 kPa after normalization of trans-aminases. RESULTS:Of the serum transaminases,the decrease in LS correlated best with the decrease in glutamic oxaloacetic transaminase (GOT). No significant chang-es in LS were observed below GOT levels of 100 U/L. After establishing the association between LS and GOT levels,we applied the rule of GOT < 100 U/L for reliable LS assessment in a second validation cohort of 101 patients with histologically confi rmed ALD. By ex-cluding those patients with GOT > 100 U/L at the time of LS assessment from this cohort,the area under the receiver operating characteristic (AUROC) for cirrhosis detection by FS improved from 0.921 to 0.945 while specificity increased from 80% to 90% at a sensitivity of 96%. A similar AUROC could be obtained for lower F3 fibrosis stage if LS measurements were restricted to patients with GOT < 50 U/L. Histological grading of inflammation did not further improve the diagnostic accuracy of LS.CONCLUSION:Coexisting steatohepatitis markedly increases LS in patients with ALD independent of fibrosis stage. Postponing cirrhosis assessment by FS during alcohol withdrawal until GOT decreases to < 100 U/mL signif icantly improves the diagnostic accuracy.	Sebastian Mueller Gunda Millonig Lucie Sarovska Stefanie Friedrich Frank M Reimann Maria Pritsch Silke Eisele Felix Stickel Thomas Longerich Peter Schirmacher Helmut Karl Seitz	2010	World Journal of Gastroenterology2010，16，8：	10
	2	TIMI myocardial perfusion grade and ST segment res-olution: association with infarct size as assessed bysingle photon emission computed tomography imaging显示文摘	ANGEJA B G GUNDA M MURPHY S A	2002	Circulation2002，105，：	1
	3	Association of the arterial access site at angioplastywith transfusion and mortality: the MORTAL study显示文摘	ANGEJA B G GUNDA M MURPHY S A	2008	Heart2008，94，：	1
	4	TIMI myocardi- al perfusion grade and ST-segment resolution: association with infarct size as assessed by single photon emission computed tomography imaging显示文摘	Angeja BG Gunda M Murphy SA etal	2002	Circulation2002，105，：	1
	5	Recent advances in myocardial contrast echocardiography显示文摘	Gunda M Mulvagh SL	2001	Curr Opin Cardiol2001，16，4：	1
	6	TIMI myocardial perfusion grade and ST segment resolution:association with infarct ize as assessed by single photon emission computed tomographyz imaging显示文摘	Angeja BG Gunda M Murphy SA	2002	Circulation2002，105，：	1
	7	National survey of palliative care in end stage renal disease in the UK显示文摘	Gunda S Thomas M Smith S	2005	Nephrol Dial Transplant2005，20，2：	1
	8	TIMI myocardial perfusion grade and ST segment resolution: Association with infarct size as assessed by single photon emission computed tomography imaging显示文摘	Angeja BG Gunda M Murphy SA	2002	Circulation2002，105，1：	1
	9	Yield and nitrogen utilization efficiency of the pseudocereals amaranth, quinoa, and buckwheat under differing nitrogen fertilization 显示文摘	Gunda Schulte auf' m Erley Hans - Peler Kaula Markus Kruse Walter Aufhammer	2005	European Journal of Agronomy2005，22，：	1
	10	Palladium-Catalyzed Synthesis of Carcinogenic Polycyclic Aromatic Hydrocarbon Epoxide-Nucleoside Adducts : The First Amination of a Chloro Nucleoside显示文摘	Lakshman M K Gunda P	2003	Org Lett2003，5，1：	1
	11	Potential role of 5-Aza-2 '- deoxycytidine induced MAGE-A4 expression in immunotherapy for an- aplastic thyroid cancer显示文摘	Gunda V Cogdill AP Bemasconi M J	2013	Surgery2013，154，6：	1
	12	Nanoparticles for biomedical imaging显示文摘	Satish K Nune Padmaja Gunda Praveen K Thallapally Ying-Ying Lin M Laird Forrest Cory J Berkland	2009	Expert Opinion on Drug Delivery2009，，11：	1
	13	Recent advances in myocardial contrast echocardiography显示文摘	Mulvagh SL		Curr Opin Cardiol0，16，4：	1
	14	TIMI myocardial perfusion grade and ST-segment res-olution:association with infarct size as assessed by single photon emission computed tomography imaging显示文摘	ANGEJA B G GUNDA M MURPHY S A	2002	Circulation2002，105，：	1

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