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| 1 | Sagittal plane analysis of the spine and pelvis in adult idiopathic scoliosis显示文摘在那里的背景是在有它联系到临床的结果的脊柱侧凸的病人的 sagittal spinopelvic 排列的重要性的增加的识别。然而,在成年自发的脊柱侧凸病人在 sagittal spinopelvic 排列看见的变化糟糕被定义。这研究被进行在成年自发的脊柱侧凸 patients.Methods 评估骨盆和脊骨的 sagittal 排列脊骨和骨盆的 sagittal 参数在 124 个病人的侧面的站的拍被分析(意味着年龄 47.4 年)与成年自发的脊柱侧凸包括胸的驼背( TK ), thoracolumbar 连接驼背( TLJ ),腰部的脊柱前凸( LL ),骨盆的发生( PI ),骶骨斜坡( SS ),骨盆倾斜(磅)并且 C7 铅锤线( C7PL )。病人根据年龄被划分成三个组:20-40 年, 41-64 年,和 65 年。参数与在正常成年人和青春期的自发的脊柱侧凸(AIS ) 的那些相比是病人。在象年龄一样的所有参数和 sagittal 参数之间的关系是在有成年自发的脊柱侧凸的病人的 PI 是的 analyzed.Results 58.1 ? 潢吗? | LI Wei-shi LI Gang CHEN Zhong-qiang Kirkham B Wood | 2010 | Chinese Medical Journal2010,,21: | 19 |
| 2 | The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration显示文摘The endosomal-lysosomal system is made up of a set of intracellular membranous compartments that dynamically interconvert,which is comprised of early endosomes,recycling endosomes,late endosomes,and the lysosome.In addition,autophagosomes execute autophagy,which delivers intracellular contents to the lysosome.Maturation of endosomes and/or autophagosomes into a lysosome creates an unique acidic environment within the cell for proteolysis and recycling of unneeded cellular components into usable amino acids and other biomolecular building blocks.In the endocytic pathway,gradual maturation of endosomes into a lysosome and acidification of the late endosome are accompanied by vesicle trafficking,protein sorting and targeted degradation of some sorted cargo.Two opposing sorting systems are operating in these processes:the endosomal sorting complex required for transport(ESCRT)supports targeted degradation and the retromer supports retrograde retrieval of certain cargo.The endosomal-lysosomal system is emerging as a central player in a host of neurodegenerative diseases,demonstrating potential roles which are likely to be revealed in pathogenesis and for viable therapeutic strategies.Here we focus on the physiological process of endosomal-lysosomal maturation,acidification and sorting systems along the endocytic pathway,and further discuss relationships between abnormalities in the endosomal-lysosomal system and neurodegenerative diseases,especially Alzheimer’s disease(AD). | Yong-Bo Hu Eric B Dammer Ru-Jing Ren Gang Wang | 2015 | Translational Neurodegeneration2015,4,1: | 4 |
| 3 | A novel method for Co(Ⅱ) and Cu(Ⅱ) analysis by capillary electrophoresis with chemiluminescence detection显示文摘Based on the fact that some metal ions can catalyze the chemiluminescence(CL)reaction of luminol with K3Fe(CN)6,a novel capillary electrophoresis CL method was developed for the determination of Co(Ⅱ)and Cu(Ⅱ).The separation was carried out with a 10 mmol/L sodium acetate solution containing 0.8 mmol/L luminol and 2.0 mmol/Lα-HIBA(adjusted to pH 4.8 by HAc solution).The post-capillary reagent was 2.0 mmol/L K3Fe(CN)6 which was adjusted to pH 13.0 by NaOH solution.Under the optimum conditions,the detection limits(S/N=3)for Co(Ⅱ)and Cu(Ⅱ)were 7.5×10-11mol/L and 7.5×10-9mol/L,with the linear range of 7.5×10-9mol/L to 1.0×10-6mol/L and 7.5×10-8mol/L to 5.0×10-5mol/L, respectively. | Xiao Ming Guo~a Xiang Dong Xu~(a,b) Hui Jing Zhang~a Yong Gang Hu~(a,*) Jie Zhang~a a Institute of Environmental Science & Engineering,Huazhong University of Science and Technology,Wuhan 430074,China b Department of Chemistry,Huazhong University of Science and Technology,Wuhan 430074,China | 2007 | Chinese Chemical Letters2007,18,9: | 3 |
| 4 | Rapid and efficient reprogramming of human fetal and adult blood CD34~ cells into mesenchymal stem cells with a single factor显示文摘进体的干细胞的皮房间的直接变换在再生药打开了新治疗学的可能性。这里,我们证明人的导致的间充质的干细胞(iMSCs ) 能高效地从绳索血(CB ) 被产生 - 或由有一个单个因素的直接 reprogramming 的成年的外部血(PB )-CD34+ 房间, OCT4。面对一个 GSK3 禁止者, 16% OCT4-transduced CD34 + 房间在 2 个星期以内被变换成 iMSCs。有效直接 reprogramming 与两 episomal 被完成调停向量的短暂 OCT4 表示和 lentiviral 调停向量的 OCT4 transduction。iMSCs 快车 MSC 标记,类似于骨头髓(BM ) 在形态学的 -MSCs,并且在 vitro multilineage 区别能力拥有,还与 BM-MSCs 相比有一个更大的 proliferative 能力。类似于 BM-MSCs,植入的 iMSCs 形式骨头和结缔组织,并且是在老鼠的 non-tumorigenic。然而, BM-MSCs 不而 iMSCs 确实形成肌肉纤维,显示 iMSCs 的一个潜在的功能的优点。另外,我们观察到 OCT4 表示的高水平为起始的 reprogramming 和最佳的 iMSC 自强被要求,当 OCT4 表示的减小为 multilineage 区别被要求时。我们的方法将贡献病人特定的 iMSCs 的产生,它能在再生药有应用。这发现可以也为血房间的直接变换便于策略的发展进临床的重要性的房间的另外的类型。 | Xianmei Meng Rui-Jun Su David J Baylink Amanda Neises Jason B Kiroyan Wayne Yuk-Wai Lee Kimberly J Payne Daila S Gridley Jun Wang K-H William Lau Gang Li Xiao-Bing Zhang | 2013 | Cell Research2013,23,5: | 2 |
| 5 | Price equilibrium and transmission in a controlled economy: a case study of the metal exchange in China显示文摘 | Gang S Butcher B | 1994 | Journal of Futures Markets1994,14,8: | 1 |
| 6 | Bile salt biotransformations by human intestinal bacteria显示文摘 | Ridlon J M gang D J Hylemon P B | 2006 | J Lipid Res2006,47,2: | 1 |
| 7 | Multiple fleet aircraft schedule recovery following hub closures显示文摘 | Thengvall B Bard J Yu Gang | 2001 | Transportation Research2001,35,2: | 1 |
| 8 | Characteristics of pchlorophenol oxidation by Fenton' s reagent显示文摘 | Kwon B G Lee D S gang N | | 0,,09: | 1 |
| 9 | Naphthalene,phenanthrene and surfactant biodegradation显示文摘 | CHEN Gang STREVETT K A VANEGAS B A | 2001 | Biodgradation2001,12,6: | 1 |
| 10 | Solid phase modifiers of the Fe( Ⅵ )cathode :effects on the super-iron battery 显示文摘 | Licht S Wang B H Gang X | 1999 | Electrochemistry Communications1999,1,11: | 1 |
| 11 | Development of anoptimized condition-based maintenance system by data fusion and reliabilily-centered maintenance 显示文摘 | NIU Gang YANG B S PECttT M | 2010 | Reliability Engineering and System Safety2010,95,7: | 1 |
| 12 | Soil organic carbon stocks in China and changes from 1980s to 2000s显示文摘 | Zu B X Jiang G Z Gang L | 2007 | Global Change Biology2007,13,: | 1 |
| 13 | Bundling of actin filaments by elongation factor 1 alpha inhibits polymerization at filament ends显示文摘 | Murray J W Edmonds B T Liu Gang | | 0,,05: | 1 |
| 14 | Microstructural character- ization and wear behavior of in situ TIC/7075 composites synthe sized by displacement reactions and spray forming显示文摘 | YANG B GANG S YANG L et at | 2011 | Materials Science and Engineering2011,528,: | 1 |
| 15 | Protection by puerarin against MPP ^+ -induced neurotoxicity in PC12 cells mediated by inhibiting mitochondrial dysfunction and caspase-3-1ike activation显示文摘 | Jiang B Ming B Y Gang L Z | 2005 | Neurosci Res2005,53,2: | 1 |
| 16 | F-actin sequesters elongation factor 1 alpha from interaction with aminoacyl-tRNA in a pH-dependent reaction显示文摘 | Liu Gang Tang Jianzhong Edmonds B T | | 0,,04: | 1 |
| 17 | DNA vaccines expressing B and T cell epitopes can protect mice from FMDV infection in the absence of specific humoral responses 显示文摘 | Borrego B Fernandez-Pacheco P Ganges L | 2006 | Vaccine2006,24,18: | 1 |
| 18 | Solutes involved in osmotic adjustment to increasing salinity in suspension cells of Alternanthera philoxeroides Griseb显示文摘 | Longstreth D J Burow G B Yu Gang | 2004 | Plant Cell Tissue and Organ Culture2004,78,: | 1 |
| 19 | Large-scale, high-resolution agricultural systems modeling using a hybrid approach combining grid computing and parallel processing 显示文摘 | ZHAO Gang BRYAN B A KING D | 2013 | Environmental Modeling and Software2013,41,: | 1 |
| 20 | Control of p-and n-type conductivity in sputter deposition of undoped ZnO显示文摘 | Gang X Willkinson J Mischuck B | 2002 | Appl Phys Lett2002,80,: | 1 |