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3篇 您的检索式:作者名="Gao Changyun"
    题名 作者 年代 出处 被引量
1Effect of oscillatory shear on polystyrene cell morphology显示文摘Gao Changyun Zhou Nanqiao Peng Xiangfang 2006Journal of Cellular Plastics2006,42,3:1
2Effects of extruder parameters and silica on physico-mechanical and foaming properties of PP/wood-fiber composites显示文摘Zhang Zhenxiu Gao Changyun Xin Zhenxiang 2012Composites Part B : Engineering2012,43,4:1
3Bioactive gelatin cryogels with BMP-2 biomimetic peptide and VEGF:A potential scaffold for synergistically induced osteogenesis显示文摘A poor biocompatibility and bioactivity of invasive materials remains major problems for biomaterialbased therapy. In this study, we introduced gelatin scaffolds carrying both bone morphogenetic protein-2(BMP-2) biomimetic peptide and vascular endothelial growth factor-165(VEGF) that achieved controlled release, cell attachment, proliferation and differentiation. To promote osteogenesis with VEGF, we designed the BMP-2 biomimetic peptide that comprised BMP-2 core sequence oligopeptide(SSVPT), phosphoserine, and synthetic cell adhesion factor(RGDS). In vitro cell experiments, the scaffold was conducive to the adhesion and proliferation of rat bone marrow mesenchymal stem cells(r BMSCs). The micro-CT3 D reconstruction of the rat cranial bone defect model showed that bone regeneration patterns occurred from one side edge towards the center area implanted with the prepared cryogel, and tissue section staining analysis demonstrated that the scaffold with double-growth factor can synergistically accelerate bone regeneration. These findings suggested that the obtained gelatin cryogel could serve as a cell-responsive platform for biomaterial-based nonbearing bone repair.Lili Wang Long Chen Jiping Wang Liying Wang Chenyu Gao Bo Li Yuanzheng Wang Jun Wu Changyun Quan 2022Chinese Chemical Letters2022,33,4:0
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