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| 1 | Levels of synthetic musk fragrances in human milk from three cities in the Yangtze River Delta in Eastern China显示文摘Synthetic musks are used as additives in many household products.After absorption into the human body,they accumulate and their concentrations in human milk reflect both the mother and her infant's exposure level.Concentrations of four synthetic musks,musk xylene(1-tert-butyl-2,6-dimethyl-2,4,6-trinitrobenzene,MX),musk ketone(4-tert-butyl-2,6-dimethyl-3,5-dinitroacetophenone,MK),1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[γ]-2-benzopyran(HHCB) and 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4tetrahydronaphthalene(AHTN),were determined in human milk samples collected from Shanghai,Wuxi,and Shaoxing in Eastern China.The four synthetic musks were found in most samples analyzed,with HHCB the dominant component followed by MX.The median(mean) values for HHCB,AHTN,MX and MK concentrations were 63(82),5(12),17(24) and 4(9) ng/g lipid weight,respectively.These data suggested the total synthetic musk contamination was low,and the distribution percentage was HHCB > MX > AHTN ≈ MK.The relative high ratio of nitro to polycylic musk indicated that nitro musks were still widely used.The musk concentrations in these cities were not significantly different from each other(p > 0.05).Principal components score plots were obtained,which showed similar exposure sources.The amount of total synthetic musks in human milk were not associated with mother's age,although HHCB was significantly correlated with AHTN(p < 0.05).Daily ingestion of HHCB,AHTN,MX and MK for infants from human milk were estimated as(2526 ± 2926),(370 ± 524),(7391 ± 832),and(277 ± 462) ng/day,respectively.Those doses were 1-2 orders of magnitude below the provisional tolerable daily intakes. | Xiaolan Zhang Gaofeng Liang Xiangying Zeng Jing Zhou Guoying Sheng Jiamo Fu | 2011 | Journal of Environmental Sciences2011，23，6： | 8 |
| 2 | Mobility control of unmanned aerial vehicle as communication relay in airborne multi-user systems显示文摘In this paper, a model-based adaptive mobility control method for an Unmanned Aerial Vehicle(UAV) acting as a communication relay is presented, which is intended to improve the network performance in airborne multi-user systems. The mobility control problem is addressed by jointly considering unknown Radio Frequency(RF) channel parameters, unknown multi-user mobility, and non-available Angle of Arrival(AoA) information of the received signal. A Kalman filter and a least-square-based estimation algorithm are used to predict the future user positions and estimate the RF channel parameters between the users and the UAV, respectively. Two different relay application cases are considered: end-to-end and multi-user communications. A line search algorithm is proposed for the former, with its stability given and proven, whereas a simplified gradient-based algorithm is proposed for the latter to provide a target relay position at each decision time step, decreasing the two-dimensional search to a one-dimensional search. Simulation results show that the proposed mobility control algorithms can drive the UAV to reach or track the optimal relay position movement, as well as improving network performance. The proposed method reflects the properties of using different metrics as objective network performance functions. | Gaofeng WU Xiaoguang GAO Xiaowei Fu Kaifang WAN Ruohai DI | 2019 | Chinese Journal of Aeronautics2019，32，6： | 4 |
| 3 | Placement of unmanned aerial vehicles as communication relays in two-tiered multi-agent system:clustering based methods显示文摘The network performance and the unmanned aerial vehicle(UAV)number are important objectives when UAVs are placed as communication relays to enhance the multi-agent information exchange.The problem is a non-deterministic polynomial hard(NP-hard)multi-objective optimization problem,instead of generating a Pareto solution,this work focuses on considering both objectives at the same level so as to achieve a balanced solution between them.Based on the property that agents connected to the same UAV are a cluster,two clustering-based algorithms,M-K-means(MKM)and modified fast search and find density of peaks(MFSFDP)methods,are first proposed.Since the former algorithm requires too much computational time and the latter one requires too many relays,an algorithm for the balanced network performance and relay number(BPN)is proposed by discretizing the area to avoid missing the optimal relay positions and defining a new local density function to reflect the network performance metric.Simulation results demonstrate that the proposed algorithms are feasible and effective.Comparisons between these algorithms show that the BPN algorithm uses fewer relay UAVs than the MFSFDP and classic set-covering based algorithm,and its computational time is far less than the MKM algorithm. | WU Gaofeng WAN Kaifang GAO Xiaoguang FU Xiaowei | 2020 | Journal of Systems Engineering and Electronics2020，31，2： | 3 |
| 4 | Analysis of Transmission Characteristics of Copper/Carbon Nanotube Composite Through-Silicon Via Interconnects显示文摘We investigated the transmission charac-teristics of Cu/CNT composite Through-silicon via (TSV) interconnects. The equivalent lumped-element circuit model was established, with the effective conductivity employed for impedance extraction. The impacts of CNT filling ratio, temperature, and other geometrical param-eters on the performance were examined.The sensitivity analysis of Cu/CNT composite TSVs was carried out. The electrical performance of Cu/CNT composite TSVs were optimized by utilizing low-permittivity dielectrics or even air-gap. | FU Kai ZHENG Jie ZHAO Wensheng HU Yue WANG Gaofeng | 2019 | Chinese Journal of Electronics2019，28，5： | 2 |
| 5 | Studies on softe-ning of heat-affected zone of pulse¤t GMA welded A1-Zn-Mg allo显示文摘 | Fu Gaofeng Tian Fuquan | 2006 | J Mater Processing Techn2006，180，21： | 1 |
| 6 | Characterization and ultraviolet-visible shielding property of samarium-cerium compounds containing Sm_(2)O_(2)S prepared by co-precipitation method显示文摘Since ultraviolet(UV)light,as well as blue light,which is part of visible light,is harmful to skin,samarium-cerium compounds containing Sm_(2)O_(2)S were synthesized by co-precipitation method.This kind of compounds blocks not only UV light,but also blue light.The minimum values of average transmittance(360-450 nm)and band gap of samarium-cerium compounds were 8.90%and 2.76 eV,respectively,which were less than 13.96%and 3.01 eV of CeO_(2).Elemental analysis(EA),X-ray diffraction(XRD),Fourier transformation infrared(FTIR),and Raman spectra determined that the samples contained Ce_(4)O_(7),Sm_(2)O_(2)S,Sm_(2)O_(3),and Sm_(2)O_(2)SO_(4).The microstructure of samples was analyzed by scanning and transmission electron microscopies(SEM and TEM).X-ray photoelectron spectrum(XPS)showed that cerium had Ce^(3+)and Ce^(4+) valence states,and oxygen was divided into lattice oxygen and oxygen vacancy,which was the direct cause of the decrease of average transmittance and band gap. | Yanping Li Xue Bian Xun Jin Peng Cen Wenyuan Wu Gaofeng Fu | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，9： | 1 |
| 7 | Synthesis and characterization of ceria nanoparticles by complex-precipitation route显示文摘Ceria(CeO_(2))nanoparticles were successfully synthesized via a simple complex-precipitation route that employs cerium chloride as cerium source and citric acid as precipitant.The elemental analysis results of carbon,hydrogen,oxygen,and cerium in the precursors were calculated,and the results revealed that the precursors were composed of Ce(OH)_(3),Ce(H_(2)Cit)_(3),or CeCit.X-ray diffraction analysis showed that all ceria nanoparticles had a face-centered cubic structure.With the molar ratio of citric acid to Ce^(3)+(n)of 0.25 and pH of 5.5,the specific surface area of the sample reached the maximum value of 83.17 m^(2)/g.Ceria nanoparticles were observed by scanning electron microscopy.Selected area electron diffraction patterns of several samples were obtained by transmission electron microscopy,and the crystal plane spacing of each low-exponent crystal plane was calculated.The ultraviolet(UV)–visible transmittance curve showed that ceria can absorb UV light and pass through visible light.Among all samples,the minimum average transmittance of ultraviolet radiation a(UVA)was 4.42%,and that of ultraviolet radiation b(UVB)was 1.56%. | Yanping Li Xue Bian Yang Liu Wenyuan Wu Gaofeng Fu | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，2： | 1 |
| 8 | Fabrication and properties of Al matrix composites strengthened by in situ alumina particulates显示文摘New aluminum matrix composites strengthened by Al2O3 particulates through stirring cast by adding NH4Al(SO4)2 to the molten aluminum have been fabricated. TEM observation shows that in-situ Al2O3 particulates are generally spherical and they are uniformly distributed in the Al matrix. Dry sliding wear test results show that the volume loss of the unreinforced Al matrix is about three times that of the Al2O3 reinforced metal matrix composite (MMC) and the volume loss of the MMC fabricated by adding Al2O3 is larger than that of the MMC by adding NH4Al(SO4)2. Lubricating sliding wear test results show that the volume loss of the MMCs increases more slowly than that of the matrix with the increasing of the load. | Gaofeng Fu Lan Jiang Ji Liu Yue Wang | 2006 | Journal of University of Science and Technology Beijing2006，13，3： | 0 |
| 9 | 组蛋白H3泛素化通过影响H3K9甲基化进而调控肝脏发育相关基因表达的机制显示文摘文章简介肝脏的发育是一个多步骤并且受到严格调控的过程。过去的研究主要集中在个体出生前肝细胞如何分裂分化,并且多以转录因子和信号通路为研究对象。相比之下,肝脏在个体出生后直至成熟的过程中,虽然肝脏的发育并未停止,但是研究资料相对匮乏。 | Gaofeng Li Tong Ji Jiang Chen Yufei Fu Lidan Hou Yan Feng Tingyue Zhang Tianyu Song Jie Zhao Yoko Endo Hui Lin 蔡秀军 仓勇 | 2018 | 科学新闻2018，0，4： | 0 |
| 10 | Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35显示文摘PC12 cell injury was induced using 20 μM amyloid β-protein 25-35 to establish a model of Alzheimer's disease. The cells were then treated with 5, 10, and 25 μM Schisandrin B. Methylthiazolyldiphenyl-tetrazolium bromide assays and Hoechst 33342 staining results showed that with increasing Schisandrin B concentration, the survival rate of PC12 cells injured by amyloid β-protein 25-35 gradually increased and the rate of apoptosis gradually decreased. Reverse transcription-PCR, immunocytochemical staining and western blot results showed that with increasing Schisandrin B concentration, the mRNA and protein expression of vacuolar protein sorting 35 and amyloid precursor protein were gradually decreased. Vacuolar protein sorting 35 and amyloid precursor protein showed a consistent trend for change. These findings suggest that 5, 10, and 25 μM Schisandrin B antagonizes the cellular injury induced by amyloid β-protein 25-35 in a dose-dependent manner. This may be caused by decreasing the expression of vacuolar protein sorting 35 and amyloid precursor protein. | Mingmin Yan Shanping Mao Huimin Dong Baohui Liu Qian Zhang Gaofeng Pan Zhiping Fu | 2012 | Neural Regeneration Research2012，7，9： | 0 |
| 11 | Effect and mechanism of Polygonatum sibiricum polysaccharide on osteogenic differentiation of bone mesenchymal stem cells(BMSCs)显示文摘Objective:To investigate the effects and mechanisms of Polygonatum sibiricum polysaccharide(PSP)on osteogenic differentiation of bone marrow mesenchymal stem cells(BMSCs).Methods:The mouse BMSCs were cultured and induced in osteoblast medium(OBM)containing finalconcentrations(0 mg/L,12.5 mg/L,25 mg/L,and 50 mg/L)of PSP.The proliferation and cytotoxicity of BMSCs were detected by MTT assay.Alkaline phosphatase(ALP)and Alizarin red S staining were performed after 7 days' ossification-inducing culture.The mRNA expressions of ALP,Runx2 and osteocalcin(OCN)were determined by fluorescence quantitative PCR(qPCR).The mRNA and protein expressions of Tafazzin(TAZ)(a key effector of Hippo pathway)were measured by qPCR and western blotting,respectively.Results:PSP was non-cytotoxicwithin the dose range of 12.5-50 mg/L and had no impact on the proliferation of BMSCs.The activity of ALP,the intensity of ALP staining,and the formation of mineralized nodules were increased by PSP treatment(25 and50 mg/L)(P<0.01).Moreover,administration of 25 mg/L PSP significantly enhanced the mRNA levels of osteoblastic differentiation makers ALP,Runx2 and OCN as well as the mRNA and protein expressions of TAZ(P<0.01).Conclusion:PSP could promote osteogenic differentiation of BMSCs,and the mechanisms might be related to the activation of TAZ in the Hippo signaling pathway. | Pingping Wu Lei Zhang Shaohui Zong Fangna Yan Yin Xiong Wenwen Fu Bo Li Gaofeng Zeng | 2018 | 广西医科大学学报2018，35，5： | 0 |
| 12 | Study on Effect of Two Different Metallic Materials Transitional Flanges on Vacuum of Beamline显示文摘The vaccum degree of 100MeV high intensity cyclotron beam line directly affects the beam quality and transmission efficiency.Because the original molecular pump of 100MeV high intensity cyclotron beam line is frequently fault,it needed to be replaced and repaired.During | ZHU Xiaofeng ZHANG Suping LYU Yinlong PAN Gaofeng FU Zhenhui | 2017 | Annual Report of China Institute of Atomic Energy2017，，1： | 0 |
| 13 | High-performance computing of 3D blasting wave propagation in underground rock cavern by using 4D-LSM on TianHe-3 prototype E class supercomputer显示文摘Parallel computing assigns the computing model to different processors on different devices and implements it simultaneously.Accordingly,it has broad applications in the numerical simulation of geotechnical engineering and underground engineering,of which models are always large-scale.With parallel computing,the computing time or the memory requirements will be reduced by splitting the original domain of the numerical model into many subdomains,which is thus named as the domain decomposition method.In this study,a cubic and equal volume domain decomposition strategy was utilized to realize the parallel computing on the distributed memory system of four-dimensional lattice spring model(4D-LSM)based on the message passing interface.With a more efficient communication strategy introduced,this study aimed at operating an one-billion-particle model on a supercomputer platform.The preprocessing procedure of the parallelized 4D-LSM was restructured and the particle generation strategy suitable for the supercomputer platform was employed to minimize the time consumption in preprocessing and calculation.On this basis,numerical calculations were performed on TianHe-3 prototype E class supercomputer at the National Supercomputer Center in Tianjin.Two fieldscale three-dimensional blasting wave propagation models were carried out,of which the numerical results verify the computing power and the advantage of the parallelized 4D-LSM in the simulation of large-scale three-dimension models.Subsequently,the time complexity and spatial complexity of 4D-LSM and other particle discrete element methods were analyzed. | Meng Fu Gaofeng Zhao | 2022 | Deep Underground Science and Engineering2022，1，1： | 0 |
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