|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ten years of sorafenib in hepatocellular carcinoma: Are there any predictive and/or prognostic markers?显示文摘Sorafenib has been considered the standard of care for patients with advanced unresectable hepatocellular carcinoma(HCC) since 2007 and numerous studieshave investigated the role of markers involved in the angiogenesis process at both the expression and genetic level and clinical aspect. What results have ten years of research produced? Several clinical and biological markers are associated with prognosis. The most interesting clinical parameters are adverse events, Barcelona Clinic Liver Cancer stage, and macroscopic vascular invasion, while several single nucleotide polymorphisms and plasma angiopoietin-2 levels represent the most promising biological biomarkers. A recent pooled analysis of two phase III randomized trials showed that the neutrophil-to-lymphocyte ratio, etiology and extra-hepatic spread are predictive factors of response to sorafenib, but did not identify any predictive biological markers. After 10 years of research into sorafenib there are still no validated prognostic or predictive factors of response to the drug in HCC. The aim of the present review was to summarize 10 years of research into sorafenib, looking in particular at the potential of associated clinical and biological markers to predict its efficacy in patients with advanced HCC. | Giorgia Marisi Alessandro Cucchetti Paola Ulivi Matteo Canale Giuseppe Cabibbo Leonardo Solaini Francesco G Foschi Serena De Matteis Giorgio Ercolani Martina Valgiusti Giovanni L Frassineti Mario Scartozzi Andrea Casadei Gardini | 2018 | World Journal of Gastroenterology2018，24，36： | 14 |
| 2 | Early gastric cancer: diagnosis, staging, and clinical impact. Evaluation of 530 patients. New elements for an updated definition and classification显示文摘 | Luca Saragoni Paolo Morgagni Andrea Gardini Caterina Marfisi Giovanni Vittimberga Domenico Garcea Emanuela Scarpi | 2013 | Gastric Cancer2013，，4： | 3 |
| 3 | Liver Resection for Hepatocellular Carcinoma on Cirrhosis: Univariate and Multivariate Analysis of Risk Factors for Intrahepatic Recurrence显示文摘 | Giorgio Ercolani Gian Luca Grazi Matteo Ravaioli Massimo Del Gaudio Andrea Gardini Matteo Cescon Giovanni Varotti Francesco Cetta Antonino Cavallari | 2003 | Annals of Surgery2003，，4： | 2 |
| 4 | On the change of periodicities in the Hicksian multiplier-accelerator model with a consumption floor显示文摘 | Tonu Puu Laura Gardini Iryna Sushko | 2006 | Chaos Solitons & Fractals2006，29，3： | 1 |
| 5 | Effect of Italy's motorcycle helmet law on traumatic brain injuries显示文摘 | Servadei F Begliomini C Gardini E | 2003 | Inj Prev2003，9，3： | 1 |
| 6 | Use of Staphylococcus xylosus as a starter culture in dried sausages:effect on the biogenic amine content显示文摘 | Gardini F Martuscelli M Crudele M A | | 0，，03： | 1 |
| 7 | Myelin oligodendrocyte glycoprotein is unique member of the immunoglibulin super family显示文摘 | Gardinier MV Amiguet P Linington C | 1992 | J Neuro Sci Res1992，33，17： | 1 |
| 8 | Biogenic amines in dry fermented sausages:a review显示文摘 | Suzzi G Gardini F | 2003 | International Journal of Food Microbiology2003，88，1： | 1 |
| 9 | Nano - sized ce-ramic inks for drop - on - demand ink - jet printing in quadrlchromy 显示文摘 | Gardini D Dondi M Costa A L | 2008 | Journal of Nanoscience and Nanotech- nology2008，8，4： | 1 |
| 10 | Flow properties of PLZTN aqueous suspensions for tape casting显示文摘 | Gardini D Deluca M Nagliati M | | 0，，05： | 1 |
| 11 | Buckwheat honeys: Screen- ing of composition and properties 显示文摘 | Federica Pasini Silvia Gardini | 2013 | Food Chemistry2013，141，3： | 1 |
| 12 | Biogenic amine content and aromatic profile of Salama da sugo,a typical cooked fermented sausage produced in Emilia Romagna Re- gion(Italy)显示文摘 | Gardini F Tabanelli G Lanciotti R | 2013 | Food Control2013，32，2： | 1 |
| 13 | Biogenic amines in dry fermented sausages: a review显示文摘 | SUZZI G GARDINI F | 2003 | Intemationai Journal of Food Microbiology2003，88，1： | 1 |
| 14 | Growth/no growth interfaces of Bacillus cereus,Staphylococcus aureus and Salmonella enteritidis in model systems based on water activity,pH,temperature and ethanol concentration显示文摘 | Rosalba Lanciotti Milena Sinigaglia Fansto Gardini | 2001 | Food Microbiology2001，18，2： | 1 |
| 15 | Antifungal activity of natural compounds in relation to their vapour pressure显示文摘 | Caccioni D R L Gardini F Lanciotti R | 1997 | Sciences Des Aliments1997，17，1： | 1 |
| 16 | Hick's trade cycle re- visited: cycles and bifurcations显示文摘 | Gallegati M Gardini L Puu T | 2003 | Mathematics and Com- puters in Simulation2003，63，： | 1 |
| 17 | Effect of trans-2- hexenal on the growth of Aspergillus flavus in relation to its concentration, temperature and water activity 显示文摘 | Gardini F Lanciotti R Guerzoni M E | 2001 | Letters in Applied Microbiology2001，33，1： | 1 |
| 18 | Ceramic Pigments for Digital Decoration Inks: an Overview 显示文摘 | Dondi M B losi M Gardini D | 2012 | Cfi-Ceramic Forum International2012，89，59： | 1 |
| 19 | Factors influencing biogenic amine production by strain of Oenococcus oeni in model system显示文摘 | GARDINI F ZACCARELLI A BELLETTI N | 2005 | Food Control2005，16，7： | 1 |
| 20 | Biogenic amines in dry fermented sausages: a review显示文摘 | Giovanna Suzzi Fausto Gardini | 2003 | Int J Food Microbiol2003，88，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员