|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Isolation and separation of HMG proteins and histones H1 and H5 and core histones by column chromatography on phosphocellulose 显示文摘 | Garg C Reeck G R | 1998 | Protein Expres Purif1998，14，2： | 2 |
| 2 | Histopathological characteristics and causes of kidney graft failure in the current era of immunosuppression显示文摘BACKGROUND The histopathological findings on the failing kidney allograft in the modern era is not well studied. In this study, we present our experience working with kidney transplant recipients with graft failure within one year of the biopsy.AIM To report the histopathological characteristics of failed kidney allografts in the current era of immunosuppression based on the time after transplant, cause of the end-stage renal disease and induction immunosuppressive medications.METHODS In a single-center observational study, we characterized the histopathological findings of allograft biopsies in kidney transplant recipients with graft failure within one year after the biopsy.RESULTS We identified 329 patients with graft failure that met the selection criteria between January 1, 2006 and December 31, 2016. The three most common biopsy findings were interstitial fibrosis and tubular atrophy(IFTA, 53%), acute rejection (AR, 43%) and transplant glomerulopathy(TG, 33%). Similarly, the three most common causes of graft failure based on the primary diagnosis were AR(40%),TG(17%), and IFTA(13%). Most grafts failed within two years of post-transplant(36%). Subsequently, approximately 10%-15% of grafts failed every two years: >2-4 years(16%), > 4-6 years(13%), > 6-8 years(11%), > 8-10 years(9%) and > 10 years(16%). AR was the most common cause of graft failure in the first six years(48%), whereas TG was the most prevalent cause of graft failure after 6 years(32%) of transplant.CONCLUSION In the current era of immunosuppression, AR is still the most common cause of early graft failure, while TG is the most prevalent cause of late graft failure. | Sandesh Parajuli Fahad Aziz Neetika Garg Sarah E Panzer Emily Joachim Brenda Muth Maha Mohamed Justin Blazel Weixiong Zhong Brad C Astor Didier A Mandelbrot Arjang Djamali | 2019 | World Journal of Transplantation2019，9，6： | 2 |
| 3 | Erythropoietin therapy after out-of-hospital cardiac arrest:A systematic review and meta-analysis显示文摘AIM To assess safety and efficacy of early erythropoietin(Epo) administration in patients with out-of-hospital cardiac arrest(OHCA).METHODS A systematic literature search was performed using PubM ed,MEDLINE,EMBASE,EBSCO,CINAHL,Web of Science and Cochrane databases,of all studies published from the inception through October 10,2016.Inclusion criteria included:(1) Adult humans with OHCA and successful sustained return of spontaneous circulation;and(2) studies including mortality/brain death,acute thrombotic events as their end points.Primary efficacyoutcome was 'brain death or Cerebral Performance Category(CPC) score of 5'.Secondary outcomes were 'CPC score 1,and 2-4','overall thrombotic events' and 'acute coronary stent thrombosis'.RESULTS We analyzed a total of 606 participants(n = 276 received Epo and n = 330 with standard of care alone) who experienced OHCA enrolled in 3 clinical trials.No significant difference was observed between the Epo and no Epo group in brain death or CPC score 5(OR = 0.77;95%CI:0.42-1.39),CPC score 1(OR = 1.16,95%CI:0.82-1.64),and CPC score 2-4(OR = 0.77,95%CI:0.44-1.36).Epo group was associated with increased thrombotic complications(OR = 2.41,95%CI:1.26-4.62) and acute coronary stent thrombosis(OR = 8.16,95%CI:1.39-47.99).No publication bias was observed.CONCLUSION Our study demonstrates no improvement in neurological outcomes and increased incidence of thrombotic events and acute coronary stent thrombosis in OHCA patients who were treated with Epo in addition to standard therapy. | Rahul Chaudhary Jalaj Garg Parasuram Krishnamoorthy Kevin Bliden Neeraj Shah Nayan Agarwal Rahul Gupta Abhishek Sharma Karl B Kern Nainesh C Patel Paul Gurbel | 2017 | World Journal of Cardiology2017，9，12： | 2 |
| 4 | Combination immunotherapy with Survivin and luteinizing hormone-releasing hormone fusion protein in murine breast cancer model显示文摘AIM To investigate the therapeutic potential of two recombinant proteins, Survivin and luteinizing hormone-releasing hormone (LHRH) fusion protein [LHRH(6 leu)-LTB] for immunotherapy of breast cancer.METHODS Murine 4 T-1 breast cancer model was used to evaluate the efficacy of recombinant proteins in vivo. Twenty four Balb/c mice were divided into 4 groups of 6 mice each. Recombinant Survivin and LHRH fusion protein, alone or in combination, were administered along with immunomodulator Mycobacterium indicus pranii (MIP) in Balb/c mice. Unimmunized or control group mice were administered with phosphate buffer saline. Each group was then challenged with syngeneic 4 T-1 cells to induce the growth of breast tumor. Tumor growth was monitored to evaluate the efficacy of immune-response in preventing the growth of cancer cells.RESULTS Preventive immunization with 20 μg recombinant Survivin and MIP was effective in suppressing growth of 4 T-1 mouse model of breast cancer (P = 0.04) but 50 μg dose was ineffective in suppressing tumor growth. However, combination of Survivin and LHRH fusion protein was more effective in suppressing tumor growth (P = 0.02) as well as metastasis in vivo in comparison to LHRH fusion protein as vaccine antigen alone.CONCLUSION Recombinant Survivin and MIP suppress tumor growth significantly. Combining LHRH fusion protein with Survivin and MIP enhances tumor suppressive effects marginally which provides evidence for recombinant Survivin and LHRH fusion protein as candidates for translating the combination cancer immunotherapy approaches. | Himani Garg Rohit Singh Hada Jagdish C Gupta G P Talwar Shweta Dubey | 2018 | World Journal of Clinical Oncology2018，9，8： | 2 |
| 5 | Chemical study of an essential oll from Murraya exotica leaves 显示文摘 | GARG S c NIGAM S S | 1970 | Riechst Aromen Koerperpfleg1970，20，： | 1 |
| 6 | Effect of rare earth(Er,Gd,Eu,Nd and La) and bismuth additives on the mechanical and piezoelectric properties of lead zirconate titanate ceramics显示文摘 | AJAI GARG AGRAWAL D C | 2001 | Mater Sci Eng2001，86，： | 1 |
| 7 | Laparoscopic repair of perforatedpeptic ulcer with delayed presentation 显示文摘 | Vaidya B B Garg C P Shah J B | 2009 | 7 Laparoendosc AdvSurg Tech A2009，19，2： | 1 |
| 8 | An experimental study on the effect of ultrasonication on viscosity and heat transfer performance of multi-wall carbonnanotube-based aqueous nanofluids 显示文摘 | Garg P Alvarado J L Marsh C | 2009 | International Journal of Heat and Mass Transfer2009，52，21： | 1 |
| 9 | Environ-ment-conscious scheduling of HPC applications on distributedcloud-oriented data centers 显示文摘 | GARG S K YEO C S ANANDASIVAM A | 2010 | Journal of Parallel and DistributedComputing2010，71，6： | 1 |
| 10 | An improved process for the purification of phosphogypsum 显示文摘 | SINGH M GARG M VERMA C L | 1996 | Construct Build Mater1996，10，： | 1 |
| 11 | On the design and development of hybrid journal bearings: a review 显示文摘 | H C Garg H B Sharda V Kumar | 2006 | Tribotest2006，12，1： | 1 |
| 12 | Inference-based scheme for controlling product end-use properties in reactive extrusion processes显示文摘 | Garge S C Wetzel M D Ogunnaike B A | 2010 | Industrial and Engineering Chemistry Research2010，49，17： | 1 |
| 13 | Optimal Power Allocation for OFDM-based Cognitive Radio with New Pri- mary Transmission Protection Criteria 显示文摘 | KANG X GARG H K LIANG Y C | 2010 | IEEE Transaction on Wireless Communication2010，9，6： | 1 |
| 14 | An improved process for the purification of phosphogypsum显示文摘 | Manjit Singh Mridul Garg C L Verma | 1996 | construction and building materials1996，10，8： | 1 |
| 15 | A study of collaboration in laser science and technology 显示文摘 | GARG K C PADHI P | 2001 | Scientometrics2001，51，2： | 1 |
| 16 | Hepatic de novo lipogenesis in stable low-birth-weight infants during exclusive breast milk feedings and during parenteral nutrition 显示文摘 | Garg M Bassilian S Bell C | 2005 | JPEN J Parenter Enteral Mutr2005，29，2： | 1 |
| 17 | Generalized traveling salesman problem through n sets of nodes 显示文摘 | Srivastava S Kumar S Garg R C | 1969 | Canadian Operational Research Society Journal1969，7，2： | 1 |
| 18 | Self--efficacy impacts self--care and HbAlc in Young adults with type 1 diabetes 显示文摘 | Johnson--Brooks C H Lewis M A Garg S | 2002 | Psychosomatic Medicine2002，64，： | 1 |
| 19 | Optimal codes of dimension 3 and 4显示文摘 | BHANDARI M C GARG M S | 1992 | IEEE Trans Inf Theory1992，38，： | 1 |
| 20 | Pulmonary embolism:diagnosis with spiral CT and ventilation perfusion scanningcorrelation with pulmonary angiographic results or clinical outcome显示文摘 | Garg K Welsh C H Feyerabend A J | 1998 | Radiology1998，208，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员