2篇
您的检索式：作者名="Gaspard Pardon"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Off-stoichiometry improves the photostructuring of thiol-enes through diffusion-induced monomer depletion显示文摘Thiol–enes are a group of alternating copolymers with highly ordered networks and are used in a wide range of applications.Here,“click”chemistry photostructuring in off-stoichiometric thiol–enes is shown to induce microscale polymeric compositional gradients due to species diffusion between non-illuminated and illuminated regions,creating two narrow zones with distinct compositions on either side of the photomask feature boundary:a densely cross-linked zone in the illuminated region and a zone with an unpolymerized highly off-stoichiometric monomer composition in the non-illuminated region.Using confocal Raman microscopy,it is here explained how species diffusion causes such intricate compositional gradients in the polymer and how offstoichiometry results in improved image transfer accuracy in thiol–ene photostructuring.Furthermore,increasing the functional group off-stoichiometry and decreasing the photomask feature size is shown to amplify the induced gradients,which potentially leads to a new methodology for microstructuring. | Mikael Hillmering Gaspard Pardon Alexander Vastesson Omkar Supekar Carl Fredrik Carlborg Birgit D.Brandner Wouter van der Wijngaart Tommy Haraldsson | 2016 | Microsystems & Nanoengineering2016，2，1： | 0 |
| 2 | Reaction injection molding of hydrophilicin-hydrophobic femtolitre-well arrays显示文摘Patterning of micro-and nanoscale topologies and surface properties of polymer devices is of particular importance for a broad range of life science applications,including cell-adhesion assays and highly sensitive bioassays.The manufacturing of such devices necessitates cumbersome multiple-step fabrication procedures and results in surface properties which degrade over time.This critically hinders their wide-spread dissemination.Here,we simultaneously mold and surface energy pattern microstructures in off-stoichiometric thiol-ene by area-selective monomer selfassembly in a rapid micro-reaction injection molding cycle.We replicated arrays of 1,843,650 hydrophilic-inhydrophobic femtolitre-wells with long-term stable surface properties and magnetically trapped beads with 75%and 87.2%efficiency in single-and multiple-seeding events,respectively.These results form the basis for ultrasensitive digital biosensors,specifically,and for the fabrication of medical devices and life science research tools,generally. | Reza Zandi Shafagh Deborah Decrop Karen Ven Arno Vanderbeke Robert Hanusa Jolien Breukers Gaspard Pardon Tommy Haraldsson Jeroen Lammertyn Wouter van der Wijngaart | 2019 | Microsystems & Nanoengineering2019，5，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员