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| 1 | Preoperative therapy in locally advanced esophageal cancer显示文摘Esophageal cancer is an aggressive malignancy associated with dismal treatment outcomes. Presence of two distinct histopathological types distinguishes it from other gastrointestinal tract malignancies. Surgery is the cornerstone of treatment in locally advanced esophageal cancer(T2 or greater or node positive); however, a high rate of disease recurrence(systemic and loco-regional) and poor survival justifies a continued search for optimal therapy. Various combinations of multimodality treatment(preoperative/perioperative, or postoperative; radiotherapy, chemotherapy, or chemoradiotherapy) are being explored to lower disease recurrence and improve survival. Preoperative therapy followed by surgery is presently considered the standard of care in resectable locally advanced esophageal cancer as postoperative treatment may not be feasible for all the patients due to the morbidity of esophagectomy and prolonged recovery time limiting the tolerance of patient. There are wide variations in the preoperative therapy practiced across the centres depending upon the institutional practices, availability of facilities and personal experiences. There is paucity of literature to standardize the preoperative therapy. Broadly, chemoradiotherapy is the preferred neo-adjuvant modality in western countries whereas chemotherapy alone is considered optimal in the far East. The present review highlights the significant studies to assist in opting for the best evidence based preoperative therapy(radiotherapy, chemotherapy or chemoradiotherapy) for locally advanced esophageal cancer. | Pankaj Kumar Garg Jyoti Sharma Ashish Jakhetiya Aakanksha Goel Manish Kumar Gaur | 2016 | World Journal of Gastroenterology2016，22，39： | 13 |
| 2 | Insect feeding deterrent and growth inhibitory activities of scopoletin isolated from Artemisia annua against Spilarctia obliqua (Lepidoptera: Noctuidae)显示文摘Artemisia annua (Asteraceae ) 由于复合 artemisinin 的存在为它的抗疟药活动是众所周知的。我们从 A 的茎部分孤立 methoxy 香豆素。annua 并且通过质量作为 scopoletin 证实了它的身份光谱数据。结构从 1H-nuclear 被建立磁性的回声(NMR ) , 13C-NMR。复合 scopoletin 为它的喂的挽留的事物和生长被评估对一只有害鳞翅类的昆虫的禁止的潜力, Spilartctia obliqua 沃克。当混合了进人工的饮食时, Scopoletin 给了 FD50 (50% 的喂的挽留的事物) 96.7 g/g 饮食的价值。S。暴露于 scopoletin 的最高的集中(250 g/g 食谱) 的 obliqua 幼虫(12-day-old ) 显示出 77.1% 喂挽留的事物。在生长禁止的试金, scopoletin 在 250 g/g 饮食的最高的剂量向 116.9% 生长抑制提供了 GI50 (50% 的生长抑制) 20.9 g/g 饮食的价值。统计分析向两个都喂威慑和生长显示出一种集中依赖者剂量反应关系禁止的活动。Artemisinin 主要在 A 的叶子被发现。annua 并且不在茎,它典型地作为废物被丢弃。因此在 A 的茎的 scopoletin 的鉴定。annua 可能作为为害虫控制的这材料的来源重要。 | Arun Kumar Tripathi Rajendra Singh Bhakuni Shikha Upadhyay Rashmi Gaur | 2011 | Insect Science2011，18，2： | 10 |
| 3 | Autochthonous halotolerant plant growth-promoting rhizobacteria promote bacoside A yield of Bacopa monnieri(L.)Nash and phytoextraction of salt-affected soil显示文摘Phytoremediation is a promising approach for reclamation of salt-affected soil.Phytoextraction is the most commonly used process,which exploits plants to absorb,immobilize,and accumulate salt in their shoots.In this study,halotolerant plant growth-promoting rhizobacteria(PGPR)were isolated from the rhizosphere of wild grasses growing naturally in salt-affected areas of Lucknow,Uttar Pradesh(India)and were tested for their efficacies of salt-tolerance and plant growth-promoting(PGP)abilities.Based on 16S rRNA sequences,the most efficient halotolerant isolates possessing PGP traits were identified as Pseudomonas plecoglossicida(KM 233646),Acinetobacter calcoaceticus(KM 233647),Bacillus flexus(KM 233648),and Bacillus safensis(KM 233652).Application of these isolates as bio-inoculants significantly(P<0.05)increased the growth and bacoside A yield of a medicinal plant,Bacopa monnieri(L.)Nash,grown on natural salt-affected soil.The phytoremediation of salt-affected soil was evident by the substantial increase in shoot Na^+:K^+ratio of bio-inoculant-treated plants.When compared to un-inoculated control plants,the soil physico-chemical properties of bio-inoculant-treated plants were improved.The shoot and root biomass(fresh and dry weights),soil enzymes,and soil nutrient parameters showed significant positive correlations with the shoot Na+:K+ratio.Consequently,the halotolerant PGPR screened in this study could be useful for the reclamation of saline soils concomitant with improved plant growth and bacoside A yield. | Umesh PANKAJ Durgesh Narain SINGH Pooja MISHRA Pooja GAUR C.S.Vivek BABU Karuna SHANKER Rajesh Kumar VERMA | 2020 | Pedosphere2020，30，5： | 9 |
| 4 | A comprehensive review on energy storage in hybrid electric vehicle显示文摘The sharp inclination in the emissions from conventional vehicles contribute to a significant increase in environmental issues,besides the energy crises and low conversion efficiency leads to the evolution of electric vehicles(EV).Hybrid electric vehicles(HEV) have efficient fuel economy and reduce the overall running cost,but the ultimate goal is to shift completely to the pure electric vehicle.Despite this,the main obstruction of HEV is energy storage capability.An EV requires high specific power(W/kg) and high specific energy(W$h/kg) to increase the distance travelled and reduce the time required for charging.The main focus of this paper is on the energy sources as these are the main components in EVs towards making them eco-friendly and cost-effective.Various topologies of EV technology such as HEVs,plug-in HEVs,and many more have been discussed.These topologies of EVs are based on the diverse combination of batteries,fuel cells,super-capacitor,flywheels,regenerative braking systems,which are used as energy sources and energy storage devices. | Shrey Verma Shubham Mishra Ambar Gaur Subhankar Chowdhury Subhashree Mohapatra Gaurav Dwivedi Puneet Verma | 2021 | Journal of Traffic and Transportation Engineering(English Edition)2021，8，5： | 6 |
| 5 | Establishment of high frequency shoot regeneration system in Himalayan poplar(Populus ciliata Wall. ex Royle) from petiole explants using Thidiazuron cytokinin as plant growth regulator显示文摘Populus species are important resources for industry and in scientific study on biological and agricultural systems. Our objective was to enhance the frequency of plant regeneration in Himalayan poplar(Populus ciliata wall. ex Royle). The effect of TDZ alone and in combination with adenine and NAA was studied on the regeneration potential of petiole explants. The explants were excised from Himalayan poplar plants grown in glasshouses. After surface sterilization the explants were cultured on shoot induction medium. High percentage shoot regeneration(86 %) was recorded on MS medium supplemented with 0.004 mg L^-1TDZ and 79.7 mg L^-1adenine. The regenerated shoots for elongation and multiplication were transferred to MS + 0.5 mg L^-1BAP + 0.2 mg L^-1IAA +0.3 mg L-1GA3. Root regeneration from shoots developed in vitro was observed on MS medium supplemented with 0.10 mg L^-1IBA. Himalayan poplar plantlets could be produced within2 months after acclimatization in a sterile mixture of sand and soil. We developed a high efficiency plant regeneration protocol from petiole explants of P. ciliata. | G. Aggarwal A. Gaur D. K. Srivastava | 2015 | Journal of Forestry Research2015，26，3： | 4 |
| 6 | Feasibility, efficacy, and adverse effects of outpatient antibacterial prophylaxis in children with acute myeloid leukemia显示文摘 | Hiroto Inaba Aditya H. Gaur Xueyuan Cao Patricia M. Flynn Stanley B. Pounds Viswatej Avutu Lindsay N. Marszal Scott C. Howard Ching‐Hon Pui Raul C. Ribeiro Randall T. Hayden Jeffrey E. Rubnitz | 2014 | Cancer2014，，13： | 3 |
| 7 | Activity of Angiogenesis Inhibitors in Metastatic Epithelioid Hemangioendothelioma:A Case Report显示文摘This report describes a patient with metastatic epithelioid hemangioendothelioma treated with bevacizumab and nanoparticle albumin-bound paclitaxel.The treatment was well tolerated and led to the stabilization of an aggressive variant of the disease. This case report is the first one that describes the activity of the combination of chemotherapy and bevacizumab in epithelioid hemangioendothelioma.Literature describing the activity of bevacizumab and other agents(thalidomide,lenalidomide,and interferon) believed to possess anti-angiogenic activities is also reviewed. | Sumit Gaur Alireza Torabi Thomas I O'Neill | 2012 | Clinical oncology and cancer resexreh2012，9，2： | 3 |
| 8 | Computational interaction analysis of organophosphorus pesticides with different metabolic proteins in humans显示文摘Pesticides have the potential to leave harmful effects on humans,animals,other living organisms,and the environment.Several human metabolic proteins inhibited after exposure to organophosphorus pesticides absorbed through the skin,inhalation,eyes and oral mucosa,are most important targets for this interaction study.The crystal structure of five different proteins,PDBIDs:3LII,3NXU,4GTU,2XJ1 and 1YXA in Homo sapiens (H.sapiens),interact with organophosphorus pesticides at the molecular level.The 3-D structures were found to be of good quality and validated through PROCHECK,ERRAT and ProSA servers.The results show that the binding energy is maximum-45.21 relative units of cytochrome P450 protein with phosmet pesticide.In terms of H-bonding,methyl parathion and parathion with acetylcholinesterase protein,parathion,methylparathion and phosmet with protein kinase C show the highest interaction.We conclude that these organophosphorus pesticides are more toxic and inhibit enzymatic activity by interrupting the metabolic pathways in H.sapiens. | Amit Kumar Sharma Karuna Gaur Rajeev Kumar Tiwari Mulayam Singh Gaur | 2011 | The Journal of Biomedical Research2011，25，5： | 3 |
| 9 | Sitagliptin,sitagliptin and metformin,or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats显示文摘Diabetic neuropathies are a family of nerve disorders caused by diabetes.Symptoms of the disease include nerve palsy,mononeuropathy,mononeuropathy multiplex,diabetic amyotrophy,painful polyneuropathy,autonomic neuropathy,and thoracoabdominal neuropathy.In this study,type 2 diabetes in rats was induced with nicotinamidestreptozotocin.Drug treatment was initiated on the d 15,with the combination regimen of metformin,pioglitazone and glimipiride or metformin and sitagliptin or sitagliptin,amitriptyline and sitagliptin and led to significantly improved glycemic control,increased grip strength and paw jumping response on d 21,28 and 35(P < 0.001).Significant increases in blood protein levels and decreases in urinary protein levels were observed in the animals treated with the different regimens on d 21,28 and 35(P < 0.001).Combined treatment of streptozotocin and nicotinamide caused marked degeneration of nerve cells,while administration of metformin and sitagliptin showed tissue regeneration and no body weight gain.In conclusion,treatment with sitagliptin and sitagliptin combined with metformin or amitriptyline results in no body weight gain,but causes an increase in grip strength and pain sensitivity,exhibits neural protection,and reverses the alteration of biochemical parameters in rats with streptozotocin-nicotinamide induced type 2 diabetes. | Ashish Kumar Sharma Akash Sharma Rita Kumari Kunal Kishore Divya Sharma Bharthu Parthsarthi Srinivasan Ashok Sharma Santosh Kumar Singh Samir Gaur Vijay Singh Jatav Prashant Sharma Varnika Srivastava Sneha Joshi Megha Joshi Prashant Kumar Dhakad Davender Singh Kanawat Akanksha Mishra Anil Sharma Dharmendra Singh Ravinder Pal Singh Himmat Singh Chawda Rambir Singh Sachin Kumar Raikwar Muneem Kumar Kurmi Pankaj Khatri Ashutosh Agarwal Arshee Munajjam | 2012 | The Journal of Biomedical Research2012，26，3： | 2 |
| 10 | Concurrent dengue and malaria due to Plasmodium falciparum and P. vivax显示文摘 | Rajeev M. Kaushik Amit Varma Reshma Kaushik Kunwar J.B.S. Gaur | 2007 | Transactions of the Royal Society of Tropical Medicine and Hygiene2007，，10： | 2 |
| 11 | Enveloping Relief Surfaces of Landslide Terrain显示文摘Two relief surfaces that envelop the rock fall region in a part of Garhwal Himalayas around Chamoli have been identified. Relative relief and absolute relief have been analyzed and the enveloping surfaces recorded at two levels of relief in the landscape. All landslide activity lies within these surfaces. The lower enveloping surface (800 m) dips due south by 7-8 degrees,due to an elevation rise of 100 meters within 12 km from south to north,i.e.,a gradient of 8 percent. The nature of the surface is smooth. The upper enveloping surface (> 2500 m) is almost parallel to the lower one but its surface is undulatory due to landslides and denudation. The area has been a seismically active region and has undergone seismic activity up until recently,as evidenced by the Chamoli earthquake of 29th March 1999. The effects of earthquakes are seen at higher levels in the form of landslide imprints on the terrain. | A.K.Pachauri Abhirup Chatterjee Reeta Gaur | 2007 | Journal of Mountain Science2007，4，3： | 2 |
| 12 | Cardioprotective activity of alcoholic extract of Tinospora cordifolia (Willd.) Miers in calcium chloride-induced cardiac arrhythmia in rats显示文摘The present study investigated the antiarrhythmic activity of alcoholic extract of Tinospora cordifolia (T.cordifolia) in CaCl 2 induced arrhythmia.CaCl 2 (25 mg/kg) was administered by intravenous infusion (iv) to produce arrhythmia in rats.The animals were then treated with T.cordifolia extract (150,250,and 450 mg/kg) and verapamil (5 mg/kg,iv).Lead II electrocardiogram was monitored.Plasma calcium,sodium and potassium levels were measured.In CaCl 2 induced arrhythmia,heart rate was decreased by 41.10%,T.cordifolia at 150,300,and 450 mg/kg decreased the heart rate by 26.30%,29.16%,and 38.29%,respectively,and verapamil reduced the heart rate by 9.70% compared to the normal group.The PQRST waves were normalized and atrial and ventricular fibrillation was controlled in rats treated with verapamil and T.cordifolia.CaCl 2 increased calcium and sodium levels and decreased potassium levels in blood.T.cordifolia dose-dependently decreased calcium and sodium levels and increased potassium levels.Hence,T.cordifolia can be used in antiarrhythmic clinical settings and beneficial in atrial and ventricular fibrillation and flutter and may be indicated in ventricular tachyarrhythmia. | Ashish Kumar Sharma Kunal Kishore Divya Sharma B.P Srinivasan Shyam Sunder Agarwal Ashok Sharma Santosh Kumar Singh Samir Gaur Vijay Singh Jatav | 2011 | The Journal of Biomedical Research2011，25，4： | 2 |
| 13 | Concurrent dengue and malaria due to Plasmodium falciparum and P. vivax显示文摘 | Rajeev M. Kaushik Amit Varma Reshma Kaushik Kunwar J.B.S. Gaur | 2007 | Transactions of the Royal Society of Tropical Medicine and Hygiene2007，，10： | 2 |
| 14 | Laparoscopic operative retroperitoneoscopy: use of a new device 显示文摘 | Gaur D D | 1992 | J Urol1992，148，4： | 1 |
| 15 | Licofelone novel analgesic and anti-inflammatory agent for osteoarthritis: an over-view 显示文摘 | GAUR K KORIL ML TYAGI LK | 2009 | J Young Pharm2009，1，1： | 1 |
| 16 | Acupressure wrist bands do not prevent postoperative nausea and vomiting after urological endoscopic surgery显示文摘 | Agarwal A Pathak K Gaur A | 2000 | Can J Anaesth2000，47，4： | 1 |
| 17 | Heavy metal induced proline accumulation and its role in a meliorating metal toxicity in Chlorella vulgaris显示文摘 | Metha S K Gaur J P | 1999 | New Phytologist1999，143，： | 1 |
| 18 | Thermotolerant phosphate solu-bilizing microorganisms and their interaction with mungbean显示文摘 | Gaind S Gaur A C | 1991 | Plant and Soil1991，133，： | 1 |
| 19 | Protective effect of naringin against ischemic reperfusion cerebral injury:possi- ble neurobehavioral, biochemical and Cellular alterations in rat brain显示文摘 | GAUR V AGGARWAL A KUMAR A | 2009 | Eur J Pharmacol2009，616，13： | 1 |
| 20 | Retroperitoneal laparoscopic pyelolithotomy for staghorn stones显示文摘 | Gaur DD Trivedi S Prabhudesai MR | 2002 | J La- paroendosc Adv Surg Tech A2002，12，4： | 1 |
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