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119篇 您的检索式:作者名="Gavin Y"
    题名 作者 年代 出处 被引量
1Role of senescence induction in cancer treatment显示文摘Cellular senescence is a form of permanent cell cycle arrest that can be triggered by a variety of cell-intrinsic and extrinsic stimuli, including telomere shortening,DNA damage, oxidative stress, and exposure to chemotherapeutic agents and ionizing radiation. Although the induction of apoptotic cell death is a desirable outcome in cancer therapy, mutations and/or deficiencies in the apoptotic signaling pathways have been frequently identified in many human cancer types,suggesting the importance of alternative apoptosis-independent therapeutic approaches for cancer treatment. A growing body of evidence has documented that senescence induction in tumor cells is a frequent response to many anticancer modalities including cyclin-dependent kinases 4/6 small molecule inhibitor-based targeted therapeutics and T helper-1 cytokine-mediated immunotherapy. This review discusses the recent advances and clinical relevance of therapy-induced senescence in cancer treatment.Shenghui Qin Bradley A Schulte Gavin Y Wang 2018World Journal of Clinical Oncology2018,9,8:2
2TGF-betal maintains suppressor function and Foxp3 expression in CD4^+ CD25^+ regulatory T cells显示文摘Marie J C Letterio J J Gavin M Rudensky A Y 2005J Exp Med2005,201,:1
3Foxp3 programs the development and function of CD4 + CD25 + regulatory T cells显示文摘 Gavin M A Rudensky A Y 2003Nature Immunology2003,4,4:1
4FoxP3 programs the development and function of CD4+CD25+ regulatory T cells显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Immunol2003,4,4:1
5Foxp3 pro- grams the development and function of CD4 + CD25 + reg- ulatory T cells显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Immunol2003,4,4:1
6FOXP3 and NFAT: partners in tolerance 显示文摘Rudensky AY Gavin M Zheng Y 2006Cell2006,126,2:1
7Foxp3 programs the development and function of CD4^+ CD25^+ regulatory T cells 显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Immunol2003,4,:1
8Foxp3 programs the development and function of CD4+CD25+ regulatory T cells显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Immunol2003,4,4:1
9Upregulation of TET1 and down- regulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients 显示文摘Dong E Gavin DP Chen Y 2012Transl Psychiatry2012,2,:1
10Foxp3 programs the development and function of CD4 + CD25 + regulatory T cells显示文摘 Gavin M A Rudensky A Y 2003Nat Immunol2003,4,4:1
11Foxp3 programs the de- velopment andfunction of CD4+CD25 regulatory T cells显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Im- munol2003,4,4:1
12Function analysis of microbial communities in aerobic - anaerobic SBR fed with different phosphorus/carbon (P/C) ratios 显示文摘Kong Y H Michael Beer Gavin N R 2002Microbiology2002,148,8:1
13Foxp3 programs the development and function of CD4^+CD25^+ regulatory T cells显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat humunol2003,4,4:1
14Foxp3 pro- grams the development and function of CD4 + CD25 + regulatory T cells显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Immunol2003,4,4:1
15Foxp3 programs the development and function of CD4+CD25+regulatory T cells显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Immunol2003,4,4:1
16Foxp3 Programs the development and function of CD4^+ CD25^+ regulatory T cells 显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Immunol2003,4,4:1
17Foxp3 pro?grams the development and function of CD4 +CD25 + regulatory T cells显示文摘Fontenot JD Gavin MA Rudensky A Y 2003Nat Immunol2003,4,4:1
18Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples显示文摘Xi Y Nakajima G Gavin E 2007RNA2007,13,10:1
19Foxp3 program the development and function of CD4^+ CD25^+ regulatory T ceils 显示文摘Fontenot J D Gavin M A Rudensky A Y 2003Nat Immunol2003,4,4:1
20Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways显示文摘Michael A Crackower Gavin Y 2002Cell2002,110,6:1
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