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| 1 | Computed tomography overestimation of esophageal tumor length: Implications for radiotherapy planning显示文摘AIM:To assess the relationship between preoperative computed tomography(CT)and postoperative pathological measurements of esophageal tumor length and the prognostic significance of CT tumor length data.METHODS:A retrospective study was carried out in 56 patients who underwent curative esophagogastrectomy.Tumor lengths were measured on the immediate preoperative CT and on the post-operative resection specimens.Inter-and intra-observer variations in CT measurements were assessed.Survival data were collected.RESULTS:There was a weak correlation between CT and pathological tumor length(r=0.30,P=0.025).CT lengths were longer than pathological lengths in 68%(38/56)of patients with a mean difference of 1.67 cm(95%CI:1.18-2.97).The mean difference in measurements by two radiologists was 0.39 cm(95% CI:-0.59-1.44).The mean difference between repeat CT measured tumor length(intra-observer variation) were 0.04 cm(95%CI:-0.59-0.66)and 0.47 cm (95%CI:-0.53-1.47).When stratified,patients not receiving neoadjuvant chemotherapy showed a strong correlation between CT and pathological tumor length(r =0.69,P=0.0014,n=37)than patients that did(r= 0.13,P=0.43,n=19).Median survival with CT tumor length>5.6 cm was poorer than with smaller tumors,but the difference was not statistically significant.CONCLUSION:Esophageal tumor length assessed using CT does not reflect pathological tumor extent and should not be the only modality used for management decisions,particularly for planning radiotherapy. | Karim Sillah Luke R Williams Hans-Ulrich Laasch Azeem Saleem Gillian Watkins Susan A Pritchard Patricia M Price Catharine M West Ian M Welch | 2010 | World Journal of Gastrointestinal Oncology2010,2,4: | 10 |
| 2 | 查看详情显示文摘 | Christopher A S Rasmus H Arfa R.M Warwick B D Gillian M S Royston G Alan J D | | 0,,01: | 1 |
| 3 | A Patient-Centered Perspective on Surgery Avoidance for Hip or Knee Arthritis:Lessons forthe Future显示文摘 | Peri J Monique A M Gillian A | 2007 | Arthritis & Rheumatism2007,57,1: | 1 |
| 4 | Genetic diversity of the biofilm covering Montacuta ferruginosa ( Mollusca, Bivalvia ) as evaluated by denaturing gradient gel electrophoresis analysis and cloning of PCR amplified gene fragment coding for 16S rDNA显示文摘 | Gillian D Speksnijder A G C L Zwart G J M | 1998 | Applied and Environmental Microbiology1998,64,9: | 1 |
| 5 | Matrix metalloproteinases in arthritic disease 显示文摘 | Gillian M Vera K Susan A | 2002 | Arthritis Res2002,4,3: | 1 |
| 6 | Matrix metalloproteinases in arthritic disease显示文摘 | Gillian M Vera K Susan A | 2002 | Arthritis Res2002,4,3: | 1 |
| 7 | Investigation of the melanocyte stimulating hormones on food intake显示文摘 | Caroline R Abbott Michela Rossi Min-Seon Kim Samaher H AlAhmed Gillian M Taylor Mohammad A Ghatei David M Smith Stephen R Bloom | 2000 | Brain Research2000,,1: | 1 |
| 8 | E-ring modified steroids as novel potent inhibitors of 17β- Hydroxysteroid dehydrogenase type 1显示文摘 | Delphine S F Gillian M A Christian B | 2005 | Journal of Medical Chemistry2005,48,18: | 1 |
| 9 | Amino terminus of reovirus nonstructural protein NS is important for ssRNA binding and nucleoprotein complex formation 显示文摘 | Gillian A L Nibert M L | 1998 | Virology1998,240,: | 1 |
| 10 | Amino terminus of reovirus nonstructural protein NS is important for ssRNA binding and nucleoprotein complex formation 显示文摘 | GILLIAN A L NIBERT M L | 1998 | Virology1998,240,: | 1 |
| 11 | Evaluation of influenza A virus receptors显示文摘 | Stephen J S Gillian M A | 2001 | International Congress Series2001,1219,: | 1 |
| 12 | Hyperdense artery sign, symptomatic infarct swelling and effect of alteplase in acute ischaemic stroke显示文摘Background Alteplase improves functional outcomes of patients with acute ischaemic stroke,but its effects on symptomatic infarct swelling,an adverse complication of stroke and the influence of CT hyperdense artery sign(HAS)are unclear.This substudy of the Third International Stroke Trial aimed to investigate the association between HAS and symptomatic infarct swelling and effect of intravenous alteplase on this association.Methods We included stroke patients whose prerandomisation scan was non-contrast CT.Raters,masked to clinical information,assessed baseline(prerandomisation)and follow-up(24-48 hours postrandomisation)CT scans for HAS,defined as an intracranial artery appearing denser than contralateral arteries.Symptomatic infarct swelling was defined as clinically significant neurological deterioration≤7 days after stroke with radiological evidence of midline shift,effacement of basal cisterns or uncal herniation.Results Among 2961 patients,HAS presence at baseline was associated with higher risk of symptomatic infarct swelling(OR 2.21;95% CI 1.42 to 3.44).Alteplase increased the risk of swelling(OR 1.69;95% CI 1.11 to 2.57),with no difference between patients with and those without baseline HAS(p=0.49).In patients with baseline HAS,alteplase reduced the proportion with HAS at follow-up(OR 0.67;95% CI 0.50 to 0.91),where HAS disappearance was associated with reduced risk of swelling(OR 0.25,95% CI 0.14 to 0.47).Conclusion Although alteplase was associated with increased risk of symptomatic infarct swelling in patients with or without baseline HAS,it was also associated with accelerated clearance of HAS,which in return reduced swelling,providing further mechanistic insights to underpin the benefits of alteplase. | Simiao Wu Grant Mair Geoff Cohen Zoe Morris Anders von Heijne Nick Bradey Lesley Cala Andre Peeters Andrew J Farrall Alessandro Adami Gillian Potter Ming Liu Richard I Lindley Peter A G Sandercock Joanna M Wardlaw the IST-3 Collaborative Group | 2021 | Stroke & Vascular Neurology2021,6,2: | 1 |
| 13 | Genetic diversity of the biofilm covering Montacuta ferruginosa ( Mollusca , Bivalvia ) as evaluated by denaturing gradient gel eleetrophoresis analysis and cloning of PCR amplified gene fragment coding for 16S rDNA 显示文摘 | GILLIAN D SPEKSNIJDER A G C L ZWART G J M | 1998 | Appl Environm Mierobiol1998,64,9: | 1 |
| 14 | New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes显示文摘 | Libby Gillian Donnelly Louise A Donnan Peter T Alessi Dario R Morris Andrew D Evans Josie M M | 2009 | Diabetes Care2009,,: | 1 |
| 15 | Matrix metalloproteinases in arthritic disease显示文摘 | Gillian M Vera K Susan A | 2002 | Arthritis Res2002,4,3: | 1 |
| 16 | Matrix metalloproteinases in arthritic disease显示文摘 | Gillian M Vera K Susan A | 2002 | Arthritis Res2002,,3: | 1 |
| 17 | Gardiner Salmonella occurrence and enterobacteriaceae counts in pig feed ingredients and compound feed from feed mills in Ireland 显示文摘 | Burnsa A M Lawlor P G Gillian E | 2015 | Preventive Veterinary Medicine2015,121,34: | 1 |
| 18 | Characterization of the AB loop region of TIMP-2 involvement in pro-MMP-2 activation显示文摘 | Magdalini R V Gillian M Richard A | 2006 | J Bio Chemistry2006,281,23: | 1 |
| 19 | Matrix metalloproteinases in arthritic disease显示文摘 | Gillian M Vera K Susan A | 2002 | Arthritis Res2002,4,3: | 1 |
| 20 | Enantioselective syn- thesis of (S)-salmeterol via asymmetric reduction of azldoketone by Pichla angusta 显示文摘 | Panayiotis A P Gillian E M | 2001 | Tetrahedron: A- symmetry2001,12,14: | 1 |