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| 1 | Classification, Expression Pattern, and E3 Ligase Activity Assay of Rice U-Box-Containing Proteins显示文摘Ubiquitin ligases 玩在由为修正选择无数适当候选人蛋白质决定 ubiquitination 系统的特性的一个中央角色。U 盒子是一最近识别了,显示出更大的存在在的活动相关的蛋白质领域比在另外的有机体种的 ubiquitin ligase。在这研究,我们用一组整个染色体分析算法从米饭染色体识别了 77 通常认为的 U 盒子蛋白质。大多数 U 盒子蛋白质基因被表示,支持旁边他们的相应表示顺序标签(EST ) 的鉴定,全身的 cDNAs,或定序的大规模平行的签名(MPSS ) 标注。用一样的算法,我们从 Arabidopsis 染色体识别了 61 U 盒子蛋白质。米饭和 Arabidopsis U 盒子蛋白质基于他们的领域作文被分类进九个主要的班。在米饭和 Arabidopsis U 盒子蛋白质之间的比较显示米饭和 Arabidopsis U 盒子蛋白质的多数有一样的领域组织。推断的发展史建立了在米饭和 Arabidopsis U-box/ARM 蛋白质之间的相同。用米饭原物系统的房间死亡试金建议那一米饭 U 盒子基因, OsPUB51,可能充当房间死亡发信号的一个否定管理者。另外,选择 U 盒子蛋白质被发现是功能的 E3 ubiquitin ligases。在此,在 genomic,水平将机能上地帮助的米饭 U 盒子蛋白质的鉴定和分析以后描绘 E3 ubiquitin ligase 的这个班。 | Li-Rong Zenga Chan Ho Park R.C. Venu Julian Gough Guo-Liang Wang | 2008 | Molecular Plant2008，1，5： | 15 |
| 2 | Electroconvulsive therapy and/or plasmapheresis in autoimmune encephalitis?显示文摘Autoimmune encephalitis is a poorly understood condition that can present with a combination of neurological and psychiatric symptoms, either of which may predominate. There are many autoantibodies associated with a variety of clinical syndromes-anti-N-Methyl-D-Aspartate receptor(NMDAR) is the commonest. Currently, the most widely used therapy is prompt plasmapheresis and steroid treatment(and tumour resection if indicated), followed by second line immunosuppression if this fails. Given the growing awareness of autoimmune encephalitis as an entity, it is increasingly important that we consider it as a potential diagnosis in order to provide timely, effective treatment. We discuss several previously published case reports and one new case. These reports examined the effects of electroconvulsive therapy(ECT) on patients with autoimmune encephalitis, particularly those in whom psychiatric symptoms are especially debilitating and refractory to standard treatment. We also discuss factors predicting good outcome and possible mechanisms by which ECT may be effective. Numerous cases, such as those presented by Wingfield, Tsutsui, Florance, Sansing, Braakman and Matsumoto, demonstrate effective use of ECT in anti-NMDAR encephalitis patients with severe psychiatric symptoms such as catatonia, psychosis, narcolepsy and stupor who had failed to respond to standard treatments alone. We also present a new case of a 71-year-old female who presented to a psychiatric unit initially with depression, which escalated to catatonia, delusions, nihilism and auditory hallucinations. After anti-NMDAR antibodies were isolated, she was treated by the neurology team with plasmapheresis and steroids, with a partial response. She received multiple sessions of ECT and her psychiatric symptoms completely resolved and she returned to her premorbid state. For this reason, we suggest that ECT should be considered, particularly in those patients who are non-responders to standard therapies. | Jessica L Gough Jan Coebergh Brunda Chandra Ramin Nilforooshan | 2016 | World Journal of Clinical Cases2016，4，8： | 8 |
| 3 | Two-dimensional electrode Sensor for glucose显示文摘 | Gough DA Joseph Y Lucisano | 1985 | Anal Chem1985，57，： | 2 |
| 4 | The simple view of reading显示文摘 | Wesley A. Hoover Philip B. Gough | 1990 | Reading and Writing1990，，2： | 2 |
| 5 | The prevalence of weight loss during (chemo)radiotherapy treatment for lung cancer and associated patient- and treatment-related factors显示文摘 | Nicole Kiss Elisabeth Isenring Karla Gough Meinir Krishnasamy | 2013 | Clinical Nutrition2013，，： | 2 |
| 6 | Barrett’s oesophagus: Intestinal metaplasia is not essential for cancer risk显示文摘 | Clive J. Kelty Martin D. Gough Quintin Van Wyk Timothy J. Stephenson Roger Ackroyd | 2007 | Scandinavian Journal of Gastroenterology2007，，11： | 2 |
| 7 | Influence of marginal configuration and porcelain addition on the fit of In-Ceram crowns显示文摘 | Shearer B Gough MB Setchell DJ | | 0，，： | 2 |
| 8 | Safety and efficacy of liraglutide in patients with type 2 diabetes and elevated liver enzymes: individual patient data meta‐analysis of the LEAD program显示文摘 | M. J. Armstrong D. D. Houlihan I. A. Rowe W. H. O. Clausen B. Elbr?nd S. C. L. Gough J. W. Tomlinson P. N. Newsome | 2012 | Aliment Pharmacol Ther2012，，2： | 2 |
| 9 | Simulation of an enzyme-based glucose sensor显示文摘 | Sha Xianzheng Gough DA | 2001 | Proc SPIE2001，4414，： | 2 |
| 10 | Structure and expression of the mRNA for mufine granulocyte -macrophage colony stimulating factor 显示文摘 | Gough N M Metcalf D Gough J | 1985 | EMBO J1985，4，3： | 1 |
| 11 | A review of human and analogue insulin trials显示文摘 | Gough S C | 2007 | Diabetes Res ClinPract2007，56，： | 1 |
| 12 | Avian encephalomyelitis virus in reared pheasants:a case study 显示文摘 | Welchman D D Cox W J Gough R E | 2009 | Avian Pathology2009，38，3： | 1 |
| 13 | Delayed initiation ofsubcutaneous insulin therapy after failure of oral glucose-low-ering agents in patients with type 2 diabetes:a population-based analysis in the UK显示文摘 | Rubino A McQuay LJ Gough SC | 2007 | Diabet Med2007，24，12： | 1 |
| 14 | A magnetic induction tomography system for samples with conductivities less than 10 S·m^-1 显示文摘 | WATSON S WILLIAMS R J GOUGH W A | 2008 | Measurement Science and Technology2008，19，04： | 1 |
| 15 | Optimisation of DNA and RNA Extraction from Achival Formalin-Fixed Tissue 显示文摘 | Coombs N J Gough A C Primrose J N | 1999 | Nucleic Acids Research1999，27，16： | 1 |
| 16 | The efficacy and safety of insulin degludec given in variable once-daily dosing intervals compared with insulin glargine and insulin degludec dosed at the same time daily:a 26-week,randomized,openlabel,parallel-group,treat-to-target trial in individuals with type 2 diabetes显示文摘 | Meneghini L Atkin SL Gough SC | 2013 | Diabetes care2013，36，4： | 1 |
| 17 | Systematic review of intes- tinal microbiota transplantation ( fecal bacteriotherapy ) for re- current Clostridium difficile infection 显示文摘 | Gough E Shaikh H Manges A R | 2011 | Clin Infect Dis2011，53，10： | 1 |
| 18 | The Simple View of Reading显示文摘 | Hoover W Gough P | 1990 | Reading and Writing1990，2，： | 1 |
| 19 | A unified framework for modern synthetic aperture imaging algorithms显示文摘 | Hawkins D W | 1996 | The International Journal of Imaging Systems and Technology1996，8，4： | 1 |
| 20 | Generalised bone loss in patients with early rheumatoid arthritis 显示文摘 | Gough AKS Lilley J Eyre S | 1994 | Lancet1994，344，： | 1 |
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